Protein Alignment TM9SF4 and tm9sf2

DIOPT Version :10

• Sequence 1: NP_609669.1
• Gene: TM9SF4 / 34778
• FlyBaseID: FBgn0028541
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_997893.1
• Gene: tm9sf2 / 334370
• ZFINID: ZDB-GENE-030131-6302
• Length: 658
• Species: Danio rerio
• Alignment Length: 669
• Identity: 290/669 - (43%)
• Similarity: 397/669 - (59%)
• Gaps: 76/669 - (11%)

  Fly    14 VLLAGVVLVADSFYVPGVAPVEFVQ----DQKIDVKAVKMT---------SSRTQLPYQYYSLRF 65
            :.|.|::..|.|||:||:|||.|.:    |:..:|...|.|         |..:.|||:|.:..|
Zfish    14 LFLCGLLQDALSFYLPGLAPVSFCKKEAGDKNSEVPDCKSTIELFVNRLDSVESVLPYEYTAFDF 78

  Fly    66 CYPKNGTLIFKSENLGEVLRGDRIVNTPYEVRMNQQVNCRLLCNQKDRPLTWSKEDSALVAE--- 127
            |..::...  .|||||:||.|:||..:||:......:.|:.:|.:     ::..:|:...|:
Zfish    79 CAEQHEKR--PSENLGQVLFGERIELSPYKFLFQNDLQCQSVCVK-----SYKTQDAGDKAKLDF 136

  Fly   128 -------RIQHEYFVHLLVDNLPVATRIVSVN------NPAEVTYEHGYRLGQV----------- 168
                   ..||    |.:|||:|| |....|.      ||       |:.:|..
Zfish   137 LKKGMLLNYQH----HWIVDNMPV-TWCYDVGDNQKFCNP-------GFPIGCYVTDTGRAKDAC 189

  Fly   169 -------DGDNIYINNHLKFILSYHMHSKDKYRVVGFEVETVSVSHKELKFHGDTCNFPDSARP- 225
                   |.|..||.||:...:.||....:   |.|..:....:..|  .|.....:.||...|
Zfish   190 VVNADFNDKDTFYIFNHVDITIFYHNVENE---VAGARLVAAKLEPK--SFKQSNVDKPDCTGPP 249

  Fly   226 -QLVNP-NGETQLYFTYSVEWKESK-VSWASRWDIYL-GMRDVQIHWFSIINSLVVVFFLSGILT 286
             .|.|. |||.::.:||||::.|.| :.||||||..| .|....|.||||:||||:|.||||::.
Zfish   250 MSLSNKFNGEIRIPYTYSVKFLEDKTIRWASRWDYILESMPHTNIQWFSIMNSLVIVLFLSGMVA 314

  Fly   287 MIMIRTLRRDIARYNTDDNIEDTLEETGWKLVHGDVFRPPKNTRLFSAIIGSGIQIFFMALITIF 351
            |||:|||.:||||||..|::||..||.|.|||||||||||:...|.|..:|||.|||.|..:|:|
Zfish   315 MIMLRTLHKDIARYNQMDSVEDAQEEFGRKLVHGDVFRPPRKGMLLSVFLGSGTQIFIMTFVTLF 379

  Fly   352 FAMLGMLSPSSRGALMTSGIFMYVFMGTIAGYYAARLYKTMKGREWKRAAFLTATLYPGIVFGTG 416
            ||.||.|||::||||||..:.::|.:||.|||.|||.||:..|.:||....|||.|.||:||...
Zfish   380 FACLGFLSPANRGALMTCAVVLWVLLGTPAGYVAARYYKSFGGEKWKTNVLLTAFLCPGVVFADF 444

  Fly   417 FFLNFFIWDKSSSGAVPFTTMISLLLLWFGISVPLVYLGFYLGYRKQPYQHPVRTNMIPRQVPTQ 481
            |.:|..:|.:.||.|:||.|::::|.|||.|||||.::|.|.|::|...:||||||.||||:|.|
Zfish   445 FVMNLILWGEGSSAAMPFGTLVAILALWFCISVPLTFIGAYFGFKKSAIEHPVRTNQIPRQIPEQ 509

  Fly   482 HWYMNAVLSTLMAGILPFGAVFIELFFVFTAIWQNQFYYLFGFLFLVFCILVVSCAQISIVMTYF 546
            .:|...:...:|.||||||.:||:|||:..:||.:|.||:||||||||.|||::|::.:|::.||
Zfish   510 SFYTKPLPGIVMGGILPFGCIFIQLFFILNSIWSHQMYYMFGFLFLVFIILVITCSEATILLCYF 574

  Fly   547 QLCGEDYRWWWRSFVVSGGSAVYVLFYSIFYFFTKLEITEFIPTLLYLGYTGLMVLTFWLLTGSI 611
            .||.|||.|.||||:.||.:|||.|.|:|.|||:||:|:....|:||.|||.:|.|.|:|.||:|
Zfish   575 HLCAEDYHWQWRSFLTSGFTAVYFLVYAIHYFFSKLQISGLASTILYFGYTMIMALIFFLFTGTI 639

  Fly   612 GFFAAYVFILRIYGAVKID 630
            ||||.:.|:.:||..||:|
Zfish   640 GFFACFWFVTKIYSVVKVD 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF4	NP_609669.1	EMP70	57..587	CDD:460774	249/568 (44%)
tm9sf2	NP_997893.1	EMP70	70..615	CDD:460774	249/568 (44%)