Protein Alignment TM9SF4 and Y41D4A.4

DIOPT Version :9

• Sequence 1: NP_001285907.1
• Gene: TM9SF4 / 34778
• FlyBaseID: FBgn0028541
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001368302.1
• Gene: Y41D4A.4 / 176983
• WormBaseID: WBGene00021506
• Length: 589
• Species: Caenorhabditis elegans
• Alignment Length: 606
• Identity: 191/606 - (31%)
• Similarity: 300/606 - (49%)
• Gaps: 86/606 - (14%)

  Fly     8 RPCLAIVLLAGVVLVADSFYVPGVAPVEFVQDQKIDVKAVKMTS-----SRTQLPYQYYSLRFCY 67
            |..::::|...:::.||          |.....::|.:.|...:     |..|..|.|:||.||.
 Worm     2 RVLISLLLFTSLLVEAD----------EHDHLYEVDEEVVLWMNTVGPYSNRQETYTYFSLPFCK 56

  Fly    68 PKNGTLIFKSENLGEVLRGDRIVNTPYEVRMNQQVNCRLLCNQKDRPLTWSKEDSALVAERIQHE 132
            .:...:....|.:||.|.|..:..:..:::........::|.:|   ||.:...:.|.|  ||:.
 Worm    57 GEKKEIGHYHETMGESLLGVELEFSGLDIKFRTNTKKTVVCEKK---LTETDYKTLLYA--IQNS 116

  Fly   133 YFVHLLVDNLPVATRIVSVNN----PAEVTYEH-----GYRLGQVDGDNIYINNHLKFILSYHMH 188
            |:..:.:|::|:...:..::|    ||...|.|     ||...||...|:..:..:.
 Worm   117 YYYQMYLDDMPIWGMVGEIDNTVNPPAYKLYTHKRLDIGYNDKQVVDVNLTTDGRVD-------- 173

  Fly   189 SKDKYRVVGFEVETVSVSHKELKFHGDTCNFPDSARPQLVNPNGETQLYFTYSVEWKESKVSWAS 253
                                                   :.|..|  |.|||.|:|.:|:|.:..
 Worm   174 ---------------------------------------IRPGAE--LTFTYEVQWSKSEVDFTK 197

  Fly   254 RWDIYLGMRDVQ--IHWFSIINSLVVVFFLSGILTMIMIRTLRRDIARYNTDDNIE----DTLEE 312
            |:|.||.....|  ||||||.||.::|.||.|::.||::||||:|.|||..:|:::    |..:|
 Worm   198 RFDKYLDPSFFQHRIHWFSIFNSFMMVVFLVGLVWMILVRTLRKDYARYQKEDSLDDLDADLGDE 262

  Fly   313 TGWKLVHGDVFRPPKNTRLFSAIIGSGIQIFFMALITIFFAMLGMLSPSSRGALMTSGIFMYVFM 377
            .|||.|||||||||....|||:.||:|..:|.:|:||...|::|... :.||:|:::.||:|...
 Worm   263 YGWKQVHGDVFRPPSMPLLFSSCIGAGYHVFTVAVITTILAIVGEFY-TERGSLLSAAIFVYAAC 326

  Fly   378 GTIAGYYAARLYKTMKGREWKRAAFLTATLYPGIVFGTGFFLNFFIWDKSSSGAVPFTTMISLLL 442
            ..:.||....:|....||.|.:...|.|.|.|.:|.|..|.:||......:|.|:|||.|:::..
 Worm   327 SPVNGYAGGSMYARFGGRHWIKQMLLGAFLLPSMVCGVAFLINFIAIYYHASRAIPFTIMLAVSA 391

  Fly   443 LWFGISVPLVYLGFYLGYRKQ-PYQHPVRTNMIPRQVPTQHWYMNAVLSTLMAGILPFGAVFIEL 506
            :...:.:||..:|..:|.... ...:|.|.|.:||.:|.:.|::...|.||..|:||||::|||:
 Worm   392 ICLFVILPLTLVGTVIGRNMAGSADYPCRVNAVPRPIPDKKWFVQPWLITLAGGVLPFGSIFIEM 456

  Fly   507 FFVFTAIWQNQFYYLFGFLFLVFCILVVSCAQISIVMTYFQLCGEDYRWWWRSFVVSGGSAVYVL 571
            :|:||:.|..:.||::||:.||..||.:....::||.:||.|..|||||.|.||.....:|.||.
 Worm   457 YFIFTSFWAYKIYYVYGFMLLVTIILSIVTVCVTIVCSYFLLNAEDYRWRWTSFACGASTAFYVY 521

  Fly   572 FYSIFYFFTKLEITEFIPTLL 592
            .||::|||.|.:...|...||
 Worm   522 MYSMYYFFFKTKYACFYSKLL 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF4	NP_001285907.1	EMP70	57..587	CDD:281048	179/545 (33%)
Y41D4A.4	NP_001368302.1	EMP70	47..533	CDD:397233	179/540 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53553
OrthoDB	1	1.010	-	-		D135708at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930