Protein Alignment TM9SF4 and ZK858.6

DIOPT Version :9

• Sequence 1: NP_001285907.1
• Gene: TM9SF4 / 34778
• FlyBaseID: FBgn0028541
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001129804.1
• Gene: ZK858.6 / 172739
• WormBaseID: WBGene00014119
• Length: 656
• Species: Caenorhabditis elegans
• Alignment Length: 623
• Identity: 353/623 - (56%)
• Similarity: 464/623 - (74%)
• Gaps: 17/623 - (2%)

  Fly    13 IVLLAGVVLVADSFYVPGVAPVEFVQDQKIDVKAVKMTSSRTQLPYQYYSLRFCYPKNGTLIFKS 77
            :::||.::.:...|||||||||:|.....|||||:|:|||...:|::|||:.||.|.||.:.:||
 Worm    46 LLVLATLIPLEQGFYVPGVAPVDFKAGDVIDVKAIKLTSSNNIMPFEYYSVPFCKPANGDIQYKS 110

  Fly    78 ENLGEVLRGDRIVNTPYEVRMNQQVNCRLLCNQKDRPLTWSKEDSALVAERIQHEYFVHLLVDNL 142
            ||||||:||||||||||...|.:...|..:|:.|     .|||:.||..|||:.||..||:||||
 Worm   111 ENLGEVMRGDRIVNTPYAFHMKKNEQCVSVCSNK-----LSKENVALFKERIRQEYSAHLIVDNL 170

  Fly   143 PVATRIVSVNNPA---EVTYEHGYRLGQVDGDN--IYINNHLKFILSYHMHSKDKYRVVGFEVET 202
            ||||    |.|||   :|.|:.|||||.: |||  :::||||:|::.||.|:...||||||||..
 Worm   171 PVAT----VINPAQSGDVYYDLGYRLGWI-GDNAKVFLNNHLQFVVKYHQHTPGLYRVVGFEVRP 230

  Fly   203 VSVSHKELKFHGDTCNFPDSARPQLVNPNGETQLYFTYSVEWKESKVSWASRWDIYLGMRDVQIH 267
            .|:|  ..|....||:.||.....:...:.|..:.|:|||.::||.|.||||||:||..:.|.||
 Worm   231 RSIS--ATKNDDGTCSMPDDGTKHVELGDSEQSVDFSYSVAFEESDVPWASRWDVYLTTKAVDIH 293

  Fly   268 WFSIINSLVVVFFLSGILTMIMIRTLRRDIARYNTDDNIEDTLEETGWKLVHGDVFRPPKNTRLF 332
            ||||:||:|||..|||.:::.::||:|||||:||.||..:|||||||||||||||||||.:..:.
 Worm   294 WFSILNSIVVVLSLSGFVSVTIVRTVRRDIAQYNRDDEEDDTLEETGWKLVHGDVFRPPPHQMIL 358

  Fly   333 SAIIGSGIQIFFMALITIFFAMLGMLSPSSRGALMTSGIFMYVFMGTIAGYYAARLYKTMKGREW 397
            ..::|:|||:..|:.|.:..||||||||:|||:||::.:|::.|||.|:||:|.|||||||||..
 Worm   359 VNMVGTGIQLLGMSAIVVVCAMLGMLSPASRGSLMSAAVFLFCFMGLISGYHAGRLYKTMKGRNP 423

  Fly   398 KRAAFLTATLYPGIVFGTGFFLNFFIWDKSSSGAVPFTTMISLLLLWFGISVPLVYLGFYLGYRK 462
            .|.|..||||:|.::.|.||.||||:..|.|||||||.||::||::||.|.:||::||||.||||
 Worm   424 IRCAVQTATLFPSLILGAGFLLNFFLIGKHSSGAVPFGTMVALLIMWFCIDMPLIFLGFYFGYRK 488

  Fly   463 QPYQHPVRTNMIPRQVPTQHWYMNAVLSTLMAGILPFGAVFIELFFVFTAIWQNQFYYLFGFLFL 527
            |||.||||||.||||||.|.|::..:.|:|:||:|||||:||||||:|.|||:|||||||||||:
 Worm   489 QPYTHPVRTNQIPRQVPEQPWFLRLIPSSLIAGVLPFGAMFIELFFIFNAIWENQFYYLFGFLFI 553

  Fly   528 VFCILVVSCAQISIVMTYFQLCGEDYRWWWRSFVVSGGSAVYVLFYSIFYFFTKLEITEFIPTLL 592
            |..||.:|.||||:|.|||.||.|:|||||||||:||||:.||:.|::||:.|||.|..|:||:|
 Worm   554 VSIILAISTAQISVVATYFSLCAENYRWWWRSFVISGGSSFYVMAYAVFYYNTKLTIEGFVPTVL 618

  Fly   593 YLGYTGLMVLTFWLLTGSIGFFAAYVFILRIYGAVKID 630
            |..|:.|:.|||:.:||:|||:|::.|:.:||.|||||
 Worm   619 YFSYSSLIALTFFFMTGTIGFYASHFFLTKIYAAVKID 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF4	NP_001285907.1	EMP70	57..587	CDD:281048	308/534 (58%)
ZK858.6	NP_001129804.1	EMP70	90..613	CDD:281048	308/534 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157336
Domainoid	1	1.000	636	1.000	Domainoid score	I77
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H21620
Inparanoid	1	1.050	732	1.000	Inparanoid score	I313
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53553
OrthoDB	1	1.010	-	-		D135708at33208
OrthoFinder	1	1.000	-	-		FOG0000597
OrthoInspector	1	1.000	-	-		oto18010
orthoMCL	1	0.900	-	-		OOG6_100462
Panther	1	1.100	-	-	LDO	PTHR10766
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X358
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.910