Protein Alignment TM9SF4 and tm9sf3

DIOPT Version :10

• Sequence 1: NP_609669.1
• Gene: TM9SF4 / 34778
• FlyBaseID: FBgn0028541
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: XP_002936010.2
• Gene: tm9sf3 / 100491663
• XenbaseID: XB-GENE-6033854
• Length: 579
• Species: Xenopus tropicalis
• Alignment Length: 586
• Identity: 205/586 - (34%)
• Similarity: 318/586 - (54%)
• Gaps: 61/586 - (10%)

  Fly    55 QLPYQYYSLRFCYPKNGTLIFKSENLGEVLRGDRIVNTPYEVRMNQQVNCRLLCNQKDRPLTWSK 119
            |..|:|:||.||.....::....|.|||.|:|..:..:..:::....|.....|   :..||..|
 Frog    45 QETYKYFSLPFCVGSKKSISHYHETLGEALQGVELEFSGLDIKFKDDVMQTSYC---EIDLTKGK 106

  Fly   120 EDSALVAERIQHEYFVHLLVDNLPVATRIVSVNNPAEVTYEHGYRLGQVD--GDNIYINNHLKFI 182
            :|:.:.|  |::.|:..:.:|:||:...:                 |:.|  |::.|:..:.|..
 Frog   107 KDAFVYA--IKNHYWYQMYIDDLPIWGIV-----------------GEADENGEDYYLWTYKKLE 152

  Fly   183 LSYHMHSKDKYRVVGFEVETVSVSHKELKFHGDTCNFPDSARPQLVNPNGETQLYFTYSVEWKES 247
            :.|:.:     |:|                   ..|.....:.:|| ||  |::..:|||:||:|
 Frog   153 IGYNGN-----RIV-------------------DVNLTSEGKVKLV-PN--TKVQMSYSVKWKKS 190

  Fly   248 KVSWASRWDIYLGMRDVQ--IHWFSIINSLVVVFFLSGILTMIMIRTLRRDIARYN----TDDNI 306
            .|.:..|:|.||.....|  ||||||.||.::|.||.|:::||::||||:|.|||:    .||..
 Frog   191 DVRFEDRFDKYLDPSFFQHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKEEEMDDMD 255

  Fly   307 EDTLEETGWKLVHGDVFRPPKNTRLFSAIIGSGIQIFFMALITIFFAMLGMLSPSSRGALMTSGI 371
            .|..:|.|||.||||||||..:..:||::||||.|||.::||.|..||:..|. :.||:::::.|
 Frog   256 RDLGDEYGWKQVHGDVFRPSSHPLMFSSLIGSGCQIFAVSLIVIIVAMIEDLY-TERGSMLSTAI 319

  Fly   372 FMYVFMGTIAGYYAARLYKTMKGREWKRAAFLTATLYPGIVFGTGFFLNFFIWDKSSSGAVPFTT 436
            |:|.....:.||:...||....||.|.:..|:.|.|.|.:|.||.||:||......:|.|:||.|
 Frog   320 FVYAATSPVNGYFGGSLYARQGGRRWIKQMFIGAFLIPAMVCGTAFFINFIAIYYHASRAIPFGT 384

  Fly   437 MISLLLLWFGISVPLVYLGFYLG--YRKQPYQHPVRTNMIPRQVPTQHWYMNAVLSTLMAGILPF 499
            |:::..:.|.:.:||..:|..||  ...|| ..|.|.|.:||.:|.:.|:|...:...:.|||||
 Frog   385 MVAVCCICFFVILPLNLVGTILGRNLAGQP-NFPCRVNAVPRPIPEKKWFMEPAVIVCLGGILPF 448

  Fly   500 GAVFIELFFVFTAIWQNQFYYLFGFLFLVFCILVVSCAQISIVMTYFQLCGEDYRWWWRSFVVSG 564
            |::|||::|:||:.|..:.||::||:.||..||.:....::||.|||.|..|||||.|.||:.:.
 Frog   449 GSIFIEMYFIFTSFWAYKIYYVYGFMMLVLVILCIVTVCVTIVCTYFLLNAEDYRWQWTSFLSAA 513

  Fly   565 GSAVYVLFYSIFYFFTKLEITEFIPTLLYLGYTGLMVLTFWLLTGSIGFFAAYVFILRIYGAVKI 629
            .:|:||..||.:|:|.|.::.....|..|.||..:......::.|:||:.....|:.:||..|||
 Frog   514 STAIYVYMYSFYYYFFKTKMYGLFQTSFYFGYMAVFSTALGIMCGAIGYMGTSAFVRKIYTNVKI 578

  Fly   630 D 630
            |
 Frog   579 D 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF4	NP_609669.1	EMP70	57..587	CDD:460774	190/539 (35%)
tm9sf3	XP_002936010.2	EMP70	47..517	CDD:460774	182/520 (35%)