DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9014 and Rnf138

DIOPT Version :9

Sequence 1:	NP_001285905.1	Gene:	CG9014 / 34777	FlyBaseID:	FBgn0028847	Length:	328	Species:	Drosophila melanogaster
Sequence 2:	NP_997506.1	Gene:	Rnf138 / 56515	MGIID:	1929211	Length:	245	Species:	Mus musculus

Alignment Length:	174	Identity:	42/174 - (24%)
Similarity:	73/174 - (41%)	Gaps:	31/174 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGFDLNCIVGHVDEELICPICTDVLEEPVQSSECEHAFCRACIDKWMIQKQI-CPVDRSGLLT-- 62
            |..:|:....:.:::..||:|.:||:.||:::.|:|.|||.|....|.:..| ||:.| |.:|
Mouse     1 MSEELSAATSYTEDDFYCPVCQEVLKTPVRTAACQHVFCRKCFLTAMRESGIHCPLCR-GSVTRR 64

  Fly    63 SHLVPVSRL-MRNMLSRLKIKCTFSQSGCAQMLALEEFRTHVAAC-----EHNPKVVVECSKGCG 121
            ....|...| :.|::.|....|..    |::.:.....|.|..:|     |:....|:.     .
Mouse    65 ERACPERALDLENIMRRFSGSCRC----CSKKIKFYRMRHHYKSCKKYQDEYGVSSVIP-----N 120

  Fly   122 MKVPKDEMSRHNCVFELRELVEKLAKEVSDLKQKQSDMEEQSSS 165
            .|:.:|.:...|            ..|.|.....::..|:.|||
Mouse   121 FKISQDSVRSSN------------RSETSASDNTETYQEDTSSS 152

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9014	NP_001285905.1	zf-C3HC4	18..55	CDD:278524	16/37 (43%)
CG9014	NP_001285905.1	USP8_interact	137..319	CDD:286082	6/29 (21%)
Rnf138	NP_997506.1	RING-HC_RNF138	14..59	CDD:319458	18/45 (40%)
		zf_C2HC_14	80..112	CDD:408358	6/35 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	128..154		7/37 (19%)
		zf-Di19	156..215	CDD:398954
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7288
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.860