DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9014 and traf6

DIOPT Version :9

Sequence 1:	NP_001285905.1	Gene:	CG9014 / 34777	FlyBaseID:	FBgn0028847	Length:	328	Species:	Drosophila melanogaster
Sequence 2:	NP_001038217.1	Gene:	traf6 / 554561	ZFINID:	ZDB-GENE-030131-5735	Length:	542	Species:	Danio rerio

Alignment Length:	318	Identity:	76/318 - (23%)
Similarity:	118/318 - (37%)	Gaps:	80/318 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 CPICTDVLEEPVQSSECEHAFCRACIDKWMIQK-QICPVDRSGLLTSHLVPVSRLMRNMLSRLKI 81
            ||||...|...|| :.|.|.||.:||.|.:... |.||||...||...|.|.:...|.:|| |.:
Zfish    71 CPICLMGLRSAVQ-TPCGHRFCDSCIRKSIRDTGQKCPVDNEVLLEEQLFPDNFAKREILS-LTV 133

  Fly    82 KCTFSQSGCAQMLALEEFRTHVAACEHNPKVVVECSKGCGMKVPKDEMSRH---NCVFELRELVE 143
            ||  |..||::.:.|.:...|::.|..   ....|.: |...||...:..|   :|:..:....:
Zfish   134 KC--SNFGCSEKMELRQLEKHLSQCRF---ATAPCPQ-CQESVPISHLDEHKSQHCLQRIMTCPD 192

  Fly   144 KLAKEVSDLKQKQSDMEEQSSS--QRREMELFQYYIAALRSTN-----------------PMLRN 189
            .....|..:||........:::  :..||||.:..:|....|:                 .|.||
Zfish   193 CAGSFVYAVKQNHEQFCPFANTVCEYCEMELIRDQLALHCDTDCLKAPVACTFSTFGCREKMTRN 257

  Fly   190 -IGEQLDRFSLMQWGH-------------GLPLANIH----TWGSLISTPDNPMHLMVRDVLRES 236
             :.:.:..|:.|...:             .:|.|..|    ..|:...:||:            .
Zfish   258 ELAQHMQEFTQMHMRYMAEFLRSQTLNNCTMPSAAAHLSSDDRGASARSPDS------------C 310

  Fly   237 GCPMHMLNM----------LVERCHEDRWPEGLMTLDDRRENQHLMSRYVTRLVPGLV 284
            .|...:||:          ||   .:|:....|...:|.::||      ||.|...||
Zfish   311 QCKQELLNLRETVLELEGRLV---RQDQQIRELCIHNDTQKNQ------VTELRRKLV 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9014	NP_001285905.1	zf-C3HC4	18..55	CDD:278524	16/37 (43%)
CG9014	NP_001285905.1	USP8_interact	137..319	CDD:286082	35/195 (18%)
traf6	NP_001038217.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	32..54
		RING	71..108	CDD:214546	16/37 (43%)
		zf-TRAF	205..262	CDD:280357	9/56 (16%)
		MATH_TRAF6	375..521	CDD:239745
		Substrate binding. /evidence=ECO:0000250	489..496
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0297
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D918518at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820