DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9014 and traf4b

DIOPT Version :9

Sequence 1:	NP_001285905.1	Gene:	CG9014 / 34777	FlyBaseID:	FBgn0028847	Length:	328	Species:	Drosophila melanogaster
Sequence 2:	NP_997982.1	Gene:	traf4b / 404035	ZFINID:	ZDB-GENE-040305-2	Length:	478	Species:	Danio rerio

Alignment Length:	388	Identity:	90/388 - (23%)
Similarity:	143/388 - (36%)	Gaps:	96/388 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 GFDLNCIVGHVDEELICPICTDVLEEPVQSSECEHAFCRACIDKWMIQKQI-CPVDRSGLLTSHL 65
            |.||. .:.....:..||:|...:.||||.|.|.|.||..|:.:::.:... ||.|:..|..:.:
Zfish     3 GLDLK-FLERPRRKFYCPLCEKPMREPVQVSTCGHRFCDTCLQEYLSEGVFTCPEDQLPLDYAKI 66

  Fly    66 VPVSRLMRNMLSRLKIKCTFSQSGCAQMLALEEFRTHVAACEHNPKVVVECSKGCGMKVPKDEMS 130
            .|...|.:.:|| |.|:|..|:.||......:..:.|::.||.|   ||.|...|.:|:.:.|:.
Zfish    67 FPDLELEQQILS-LPIRCIHSEEGCRWTAQNKLLQAHLSVCEFN---VVSCPNRCSVKLLRRELP 127

  Fly   131 ---RHNCVFELREL-----VEKLAKEVSDLKQ----KQSDMEEQSSSQRREMELF-QYYIA-ALR 181
               :|:|.  .|:|     .|:...|..:..|    ::|...|.....|....|. |:.:: .|:
Zfish   128 EHLQHDCA--KRKLHCDHCGEQFTGEAYENHQGVCPEESVYCENKCGARMVRRLLAQHSVSECLK 190

  Fly   182 STNP-----------MLRNIGEQLDRFSLMQWGHGLPLANIHTWGSLISTPDNPM-HL------- 227
            ...|           .::|..:|..||         |:...:..|:...|.|..| |:
Zfish   191 RKLPCRYCKKEFLYDTIQNHQQQCPRF---------PMQCPNRCGTPGITRDTLMAHVKEGCSTA 246

  Fly   228 MVRDVLRESGCPMHMLNMLVERCHEDRWPEGLMTL------------DDRRENQHL--------- 271
            ||....:|:||........|.|..|:..|..|..|            |.||..:.|
Zfish   247 MVLCPFKEAGCKHRSPKTGVARHLEEAAPTHLSLLCGLVNRQRLELRDLRRRMEELSGSRDGTLL 311

  Fly   272 --MSRYVTRLVPGLVIGKPCVVVL-----------------------GGENTHMPENLRPILG 309
              ::.:..||.........|:.:.                       .||:|||...||.:.|
Zfish   312 WKLTDFSQRLQEAKTRTSGCLELFSPAFYSHNYGYRLQVSAFLNGNGSGEDTHMSVYLRVLPG 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9014	NP_001285905.1	zf-C3HC4	18..55	CDD:278524	14/37 (38%)
CG9014	NP_001285905.1	USP8_interact	137..319	CDD:286082	48/249 (19%)
traf4b	NP_997982.1	RING	18..55	CDD:238093	13/36 (36%)
		zf-TRAF	102..156	CDD:280357	16/58 (28%)
		zf-TRAF	156..210	CDD:280357	8/53 (15%)
		zf-TRAF	210..269	CDD:280357	15/67 (22%)
		MATH_TRAF4	308..471	CDD:239750	11/67 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0297
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D918518at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820