DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9014 and Traf3

DIOPT Version :9

Sequence 1:	NP_001285905.1	Gene:	CG9014 / 34777	FlyBaseID:	FBgn0028847	Length:	328	Species:	Drosophila melanogaster
Sequence 2:	XP_038968511.1	Gene:	Traf3 / 362788	RGDID:	1304633	Length:	610	Species:	Rattus norvegicus

Alignment Length:	269	Identity:	60/269 - (22%)
Similarity:	94/269 - (34%)	Gaps:	95/269 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 VDEELICPICTDVLEEPVQSSECEHAFCRACIDKWM---------IQKQIC--PVDRSGLLTSHL 65
            |:::..|..|..||..|.| :||.|.||.:|:...:         .|:.|.  .|.:.......:
  Rat    89 VEDKYKCEKCRLVLCNPKQ-TECGHRFCESCMAALLSSSSPKCTACQESIIKDKVFKDNCCKREI 152

  Fly    66 VPVSRLMRN-------------MLSRLKIKCTFSQ-----SGCAQMLALEEFRTHV--------A 104
            :.:....||             :|..||.:|.|.:     :.|.:.:...:.|.||        |
  Rat   153 LALQIYCRNEGRGCVEQLTLGHLLVHLKNECQFEELPCLRADCKEKVLRRDLRDHVEKACKYREA 217

  Fly   105 ACEH-----------------NPKVVVECSKGCGMK-VPKDEMS----------------RHNCV 135
            .|.|                 .|.|||.|...|.:: :.:.|:|                |:.||
  Rat   218 TCAHCKSQVPMITLQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCV 282

  Fly   136 FE--------------------LRELVEKLAKEVSDLKQKQSDMEEQSSSQRREMELFQYYIAAL 180
            |:                    |:|....|.|:|| |.|.:| :|:..|.|....::..:.|...
  Rat   283 FQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVS-LLQNES-VEKNKSIQSLHNQICSFEIEIE 345

  Fly   181 RSTNPMLRN 189
            |. ..||||
  Rat   346 RQ-KEMLRN 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9014	NP_001285905.1	zf-C3HC4	18..55	CDD:278524	14/47 (30%)
CG9014	NP_001285905.1	USP8_interact	137..319	CDD:286082	18/73 (25%)
Traf3	XP_038968511.1	RING-HC_TRAF3	93..134	CDD:319554	12/41 (29%)
		zf-TRAF	178..234	CDD:280357	11/55 (20%)
		zf-TRAF	239..289	CDD:424248	12/49 (24%)
		Smc	<294..>475	CDD:224117	18/63 (29%)
		MATH_TRAF3	420..605	CDD:239746
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D918518at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920