DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9014 and Traf7

DIOPT Version :9

Sequence 1:	NP_001285905.1	Gene:	CG9014 / 34777	FlyBaseID:	FBgn0028847	Length:	328	Species:	Drosophila melanogaster
Sequence 2:	XP_006246044.1	Gene:	Traf7 / 360491	RGDID:	1559653	Length:	670	Species:	Rattus norvegicus

Alignment Length:	326	Identity:	62/326 - (19%)
Similarity:	106/326 - (32%)	Gaps:	124/326 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 ELICPICTDVLEEPVQSSECEHAFCRACIDKWMIQKQICPVDRSGLLTSHLVPVSRL-MRNMLSR 78
            :|.|.:|..|.::||.:: |.|.|||.|    .::.:.||||.:.|    .|.|:.: :...:..
  Rat   128 KLCCQLCCSVFKDPVITT-CGHTFCRRC----ALKSEKCPVDNAKL----TVVVNNIAVAEQIGE 183

  Fly    79 LKIKC---------------TFSQSGCAQMLALEEFRTHVAACEHNPKVVVEC------------ 116
            |.|.|               .....||...:.|...:.|.::|::.|   |.|
  Rat   184 LFIHCRHGCRAAGTGKPGVFEVDPRGCPFTIKLSARKDHESSCDYRP---VRCPNNPSCPPLLKM 245

  Fly   117 ----------------SK-GCGMKVPKDEMSRH--NCVFE------------------------- 137
                            || ||.....:|....|  .|.||
  Rat   246 NLEAHLKECEHIKCPHSKYGCTFIGNQDTYETHLETCRFEGLKEFLQQTDDRFHEMHVALAQKDQ 310

  Fly   138 ----LRELVEKLAKEVSDLK-----------QKQSDMEEQSSSQRREMELFQYYIAALRSTNPML 187
                ||.::.||::::..|:           :.||.:.|.....||:..:.          |..|
  Rat   311 EIAFLRSMLGKLSEKIDQLEKSLELKFDVLDENQSKLSEDLMEFRRDASML----------NDEL 365

  Fly   188 RNIGEQLDRFSLMQW-------------GHGLPL--ANIHTWGSLISTPDNPMHLMVRDVLRESG 237
            .:|..:|:...|..:             ||..|:  ..:::.|.|:.:..:...:.|.|......
  Rat   366 SHINARLNMGILGSYDPQQIFKCKGTFVGHQGPVWCLCVYSMGDLLFSGSSDKTIKVWDTCTTYK 430

  Fly   238 C 238
            |
  Rat   431 C 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9014	NP_001285905.1	zf-C3HC4	18..55	CDD:278524	12/36 (33%)
CG9014	NP_001285905.1	USP8_interact	137..319	CDD:286082	24/157 (15%)
Traf7	XP_006246044.1	mRING-HC-C3HC3D_TRAF7	129..165	CDD:319558	15/40 (38%)
		Sina	207..>281	CDD:418524	14/76 (18%)
		DD_cGKI	282..322	CDD:418404	5/39 (13%)
		PRK03918	283..>373	CDD:235175	15/99 (15%)
		WD40	388..668	CDD:238121	8/44 (18%)
		WD40 repeat	443..477	CDD:293791
		WD40 repeat	482..517	CDD:293791
		WD40 repeat	527..556	CDD:293791
		WD40 repeat	562..596	CDD:293791
		WD40 repeat	604..639	CDD:293791
		WD40 repeat	646..668	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0297
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810