DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9014 and Traf7

DIOPT Version :9

Sequence 1:	NP_001285905.1	Gene:	CG9014 / 34777	FlyBaseID:	FBgn0028847	Length:	328	Species:	Drosophila melanogaster
Sequence 2:	NP_001165584.1	Gene:	Traf7 / 224619	MGIID:	3042141	Length:	669	Species:	Mus musculus

Alignment Length:	326	Identity:	62/326 - (19%)
Similarity:	106/326 - (32%)	Gaps:	124/326 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 ELICPICTDVLEEPVQSSECEHAFCRACIDKWMIQKQICPVDRSGLLTSHLVPVSRL-MRNMLSR 78
            :|.|.:|..|.::||.:: |.|.|||.|    .::.:.||||.:.|    .|.|:.: :...:..
Mouse   127 KLCCQLCCSVFKDPVITT-CGHTFCRRC----ALKSEKCPVDNAKL----TVVVNNIAVAEQIGE 182

  Fly    79 LKIKC---------------TFSQSGCAQMLALEEFRTHVAACEHNPKVVVEC------------ 116
            |.|.|               .....||...:.|...:.|.::|::.|   |.|
Mouse   183 LFIHCRHGCHAAGTGKPGVFEVDPRGCPFTIKLSARKDHESSCDYRP---VRCPNNPSCPPLLKM 244

  Fly   117 ----------------SK-GCGMKVPKDEMSRH--NCVFE------------------------- 137
                            || ||.....:|....|  .|.||
Mouse   245 NLEAHLKECEHIKCPHSKYGCTFIGNQDTYETHLETCRFEGLKEFLQQTDDRFHEMHVALAQKDQ 309

  Fly   138 ----LRELVEKLAKEVSDLK-----------QKQSDMEEQSSSQRREMELFQYYIAALRSTNPML 187
                ||.::.||::::..|:           :.||.:.|.....||:..:.          |..|
Mouse   310 EIAFLRSMLGKLSEKIDQLEKSLELKFDVLDENQSKLSEDLMEFRRDASML----------NDEL 364

  Fly   188 RNIGEQLDRFSLMQW-------------GHGLPL--ANIHTWGSLISTPDNPMHLMVRDVLRESG 237
            .:|..:|:...|..:             ||..|:  ..:::.|.|:.:..:...:.|.|......
Mouse   365 SHINARLNMGILGSYDPQQIFKCKGTFVGHQGPVWCLCVYSMGDLLFSGSSDKTIKVWDTCTTYK 429

  Fly   238 C 238
            |
Mouse   430 C 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9014	NP_001285905.1	zf-C3HC4	18..55	CDD:278524	12/36 (33%)
CG9014	NP_001285905.1	USP8_interact	137..319	CDD:286082	24/157 (15%)
Traf7	NP_001165584.1	RING	130..162	CDD:214546	12/36 (33%)
		Sina	206..>279	CDD:302762	14/75 (19%)
		DD_cGKI	281..321	CDD:213458	5/39 (13%)
		WD40	<379..667	CDD:225201	8/52 (15%)
		WD40	387..667	CDD:238121	8/44 (18%)
		WD40 repeat	442..476	CDD:293791
		WD40 repeat	481..516	CDD:293791
		WD40 repeat	526..555	CDD:293791
		WD40 repeat	561..595	CDD:293791
		WD40 repeat	603..638	CDD:293791
		WD40 repeat	645..667	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0297
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810