DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9014 and Traf5

DIOPT Version :9

Sequence 1:	NP_001285905.1	Gene:	CG9014 / 34777	FlyBaseID:	FBgn0028847	Length:	328	Species:	Drosophila melanogaster
Sequence 2:	NP_035763.2	Gene:	Traf5 / 22033	MGIID:	107548	Length:	558	Species:	Mus musculus

Alignment Length:	305	Identity:	61/305 - (20%)
Similarity:	107/305 - (35%)	Gaps:	88/305 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VGHVDEELICPICTDVLEEPVQSSECEHAFCRACID--KWMIQKQICPVDRSGLLTSHLVPVSRL 71
            |..::|...|..|..||..|.|:. |.|.||:.||.  :.:....|||||:..:....:...:..
Mouse    36 VEQLEERYKCAFCHSVLHNPHQTG-CGHRFCQQCIRSLRELNSVPICPVDKEVIKPQEVFKDNCC 99

  Fly    72 MRNMLSRLKIKCTFSQSGCAQMLALEEFRTHVAAC------------------------------ 106
            .|.:|: |.:.|. :..||...:.|..|:.|:..|
Mouse   100 KREVLN-LHVYCK-NAPGCNARIILGRFQDHLQHCSFQAVPCPNESCREAMLRKDVKEHLSAYCR 162

  Fly   107 ---------------------EHN--PKVVVECSKGCGMKVPKDEMSRH---------NCVF--- 136
                                 |.|  |...|.|...|...:|:..::.|         :|.|
Mouse   163 FREEKCLYCKRDIVVTNLQDHEENSCPAYPVSCPNRCVQTIPRARVNEHLTVCPEAEQDCPFKHY 227

  Fly   137 ------ELRELVEKLAKEVSD----LKQKQSDMEEQSSSQRREMELFQYYIAALRSTNPMLRNIG 191
                  :...|:|.....:.|    :.:|...:|::.|...:.:|..:..|..|..|   ::...
Mouse   228 GCTVKGKRGNLLEHERAALQDHMLLVLEKNYQLEQRISDLYQSLEQKESKIQQLAET---VKKFE 289

  Fly   192 EQLDRFSLMQWGHGLPLANIHTWGSLISTPDNP--MHLMVRDVLR 234
            ::|.:|:.|...:|..|:|:.   :|.|..|..  :...||.:|:
Mouse   290 KELKQFTQMFGRNGTFLSNVQ---ALTSHTDKSAWLEAQVRQLLQ 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9014	NP_001285905.1	zf-C3HC4	18..55	CDD:278524	14/38 (37%)
CG9014	NP_001285905.1	USP8_interact	137..319	CDD:286082	22/104 (21%)
Traf5	NP_035763.2	mRING-HC-C3HC3D_TRAF5	43..85	CDD:319556	16/42 (38%)
		zf-TRAF	128..183	CDD:280357	2/54 (4%)
		zf-TRAF	185..241	CDD:424248	10/55 (18%)
		Smc	<237..>419	CDD:224117	22/101 (22%)
		Interaction with EIF2AK2/PKR. /evidence=ECO:0000250	345..558
		MATH_TRAF5	404..551	CDD:239749
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910