DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG9014 and Lnx1

DIOPT Version :9

Sequence 1:NP_001285905.1 Gene:CG9014 / 34777 FlyBaseID:FBgn0028847 Length:328 Species:Drosophila melanogaster
Sequence 2:NP_001153049.1 Gene:Lnx1 / 16924 MGIID:1278335 Length:728 Species:Mus musculus


Alignment Length:374 Identity:77/374 - (20%)
Similarity:139/374 - (37%) Gaps:112/374 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 VDEELICPICTDVLEEPVQSSECEHAFCRACIDKWMIQKQICPVDRSGLLTSHLVPVSRLMRNML 76
            ||::|||.||...|.:|: .:.|.|.:|..|:..::::|..|||||..::..|....|.|:..:|
Mouse    39 VDDDLICHICLQALLDPL-DTPCGHTYCTLCLTNFLVEKDFCPVDRKPVVLQHCKKSSILVNKLL 102

  Fly    77 SRLKIKCTFSQSGCAQMLALEEFRTHV-AACEHNPKVVVECSKGC---GMKVPKDEMSRHNCVFE 137
            ::|.:.|.|::. |.::|...:.:.|. .:|           ||.   |:...:...|:..|...
Mouse   103 NKLLVTCPFTEH-CTEVLQRCDLQHHFQTSC-----------KGASHYGLTKDRKRRSQDGCPDG 155

  Fly   138 LRELV-EKLAKEVS--------------DLKQKQSDME----------------------EQSSS 165
            ...|: ..|:.|||              |.....|.:|                      |:|:.
Mouse   156 CASLMATTLSPEVSAAATISLMTDEPGLDNPAYVSSVEDGEPVANSSDSGRSNRTRARPFERSTM 220

  Fly   166 QRREMELFQYYIAALRST---------------NPMLRNIGEQLDR-FSLMQWGHGLPLANIHTW 214
            :.|..:.....::|||.|               |.....:.|...| |.|:..|.   :.:|.  
Mouse   221 RSRSFKKINRALSALRRTKSGSVVANHVDQGRDNSENTTVPEVFPRLFHLIPDGE---ITSIK-- 280

  Fly   215 GSLISTPDNPMHLMVRDVLRESGCPMHMLNMLVERCHEDRWPEGLMTLDDR------------RE 267
               |:..|....|.:|.|   .|....:::::::..:.|    |::..|.|            .:
Mouse   281 ---INRADPSESLSIRLV---GGSETPLVHIIIQHIYRD----GVIARDGRLLPGDIILKVNGMD 335

  Fly   268 NQHLMSRYVTRLVPGLVIGKPCVVV----------LGGENTHMPENLRP 306
            ..::...|..||     :.:||.|:          ....|.|:|::..|
Mouse   336 ISNVPHNYAVRL-----LRQPCQVLRLTVLREQKFRSRSNAHVPDSYGP 379

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG9014NP_001285905.1 zf-C3HC4 18..55 CDD:278524 11/36 (31%)
USP8_interact 137..319 CDD:286082 42/245 (17%)
Lnx1NP_001153049.1 mRING-HC-C3HC3D_LNX1 42..83 CDD:319693 15/41 (37%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 185..220 4/34 (12%)
NPXY motif 185..188 0/2 (0%)
Interaction with MAGEB18. /evidence=ECO:0000250 186..244 9/57 (16%)
PDZ_signaling 276..360 CDD:238492 17/100 (17%)
PDZ_signaling 384..464 CDD:238492
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 481..500
PDZ_signaling 506..589 CDD:238492
PDZ_signaling 637..721 CDD:238492
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0297
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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