Protein Alignment Gpo3 and Gpd2

DIOPT Version :10

• Sequence 1: NP_609667.2
• Gene: Gpo3 / 34776
• FlyBaseID: FBgn0028848
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_034404.3
• Gene: Gpd2 / 14571
• MGIID: 99778
• Length: 727
• Species: Mus musculus
• Alignment Length: 653
• Identity: 231/653 - (35%)
• Similarity: 372/653 - (56%)
• Gaps: 47/653 - (7%)

  Fly     5 PSRAEHVNALK-AEEFDVLIIGGGAVGCGCAVDAACRGLKTALIEAEDFASGSSSRTSKLIDGSG 68
            |||...:..|| ..|||:|:|||||.|||||:||..|||||||:|.:||:||:|||::|||.|..
Mouse    55 PSREAQLMTLKNTPEFDILVIGGGATGCGCALDAVTRGLKTALVERDDFSSGTSSRSTKLIHGGV 119

  Fly    69 SYLGTALREKDVEQLYIMLQMMSERVTMLKNAPHLNRIQPMIIPIYSFLQMPCTWLGLKVYDWIS 133
            .||..|:...||||..::.:.:.||..:|:.||||:...|:::|:|.:.|:|..|:|:|:||.::
Mouse   120 RYLQKAIMNLDVEQYRMVKEALHERANLLEIAPHLSAPLPIMLPLYKWWQLPYYWVGIKMYDLVA 184

  Fly   134 AASNIRGSHIISREATMYEFPLLKTDGLRGGVVYYDGQVDDARMCVALVMTAVALGANVGNHMEV 198
            .:..::.|:::|:...:..||:|:.|.|.|.:||||||.:||||.:|:.:||...||...|:|||
Mouse   185 GSQCLKSSYVLSKSRALEHFPMLQKDKLVGAIVYYDGQHNDARMNLAIALTAARYGAATANYMEV 249

  Fly   199 VEIM----PQEGCCRV--VSVKDKISCEQFYIQSKAVINATGSSTDAIRQMDKEGTAPILLPTLE 257
            |.::    |:.|..||  ...||.::.::|.:::|.||||:|..||::|:||.:...||..|:..
Mouse   250 VSLLKKTDPETGKERVSGARCKDVLTGQEFDVRAKCVINASGPFTDSVRKMDDKNVVPICQPSAG 314

  Fly   258 TQVSLPRYFGSGHYGLLSPALKNDDLTVYMVPFENHMVLGSREVDLDEVSSRGSPTPDPDDVDCL 322
            ..:.:|.|:...:.|||.|| .:|...::.:|:|...:.|:.:...|...   .|.|..:|::.:
Mouse   315 VHIVMPGYYSPENMGLLDPA-TSDGRVIFFLPWEKMTIAGTTDTPTDVTH---HPIPSEEDINFI 375

  Fly   323 LEAAKKRMDPCVELGRCHVLSAWTAIKASVSCPTDKENDDDKRGTPINSYMIEVSPDGLITLAGG 387
            |...:..:...||:.|..||:||:.|:..|:.|...:.....|     ::::::|..||||:|||
Mouse   376 LNEVRNYLSSDVEVRRGDVLAAWSGIRPLVTDPKSADTQSISR-----NHVVDISDSGLITIAGG 435

  Fly   388 RWSSYRVMAADAVDLAIKSCGLCDDHVTSSWTQDLKLDGAESWCCMLPLEFVQDYGVPMDVAHHI 452
            :|::||.||.|.||.|:|...|   :...|.|..|.|.|.:.|...|.:..|||||:..:||.|:
Mouse   436 KWTTYRSMAEDTVDAAVKFHNL---NAGPSRTVGLFLQGGKDWSPTLYIRLVQDYGLESEVAQHL 497

  Fly   453 SDSYGYNGHALFSQA-------PDLKKRLHPSFPYIEAEIQYAMRNEYACTLVDIIARRLRIAFV 510
            :.:||.....:...|       |.:..||...|||||||::|.:: |||||.||:|:||.|:||:
Mouse   498 AKTYGDKAFEVAKMASVTGKRWPVVGVRLVSEFPYIEAEVKYGIK-EYACTAVDMISRRTRLAFL 561

  Fly   511 DAAATLHMLPRILKIMAGENGWDEEEQKEQMVAAQEFLVRQMGLGSIVQPRSTSK---------S 566
            :..|....||||:::|..|..|.|..::|::..|..||..:||..|..:..:.|.         .
Mouse   562 NVQAAEEALPRIVELMGRELNWSELRKQEELETATRFLYYEMGYKSRTEQLTDSTEISLLPSDID 626

  Fly   567 KPKKK-----GSSEGCCCRAAVRRGARSYSMEISKK-----ICVQPLVQHRSMS-SMFLPLMTSL 620
            :.||:     ...:|......|:|...|.::::.:.     :|...|.::..:. ..||.||:::
Mouse   627 RYKKRFHKFDEDEKGFITIVDVQRVLESINVQMDENTLHEILCEVDLNKNGQVELHEFLQLMSAV 691

  Fly   621 SYG 623
            ..|
Mouse   692 QKG 694

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gpo3	NP_609667.2	DAO	3..548	CDD:477422	212/556 (38%)
Gpd2	NP_034404.3	DAO	1..599	CDD:477422	212/556 (38%)
		EFh	627..689	CDD:238008	11/61 (18%)