DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ics and PIRL7

DIOPT Version :9

Sequence 1:	NP_001285902.1	Gene:	ics / 34774	FlyBaseID:	FBgn0028546	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_194717.2	Gene:	PIRL7 / 829110	AraportID:	AT4G29880	Length:	373	Species:	Arabidopsis thaliana

Alignment Length:	270	Identity:	86/270 - (31%)
Similarity:	129/270 - (47%)	Gaps:	38/270 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 PVSAKMSKAKKVLDEARETHNPELDLADKGLSSFEELPGLFNMSNITRLTLSHNKISVISPGI-A 70
            |:|..:|......:...|.....::|:...|.|... |.| |::||.:|.||:|.|..|...: |
plant    35 PLSPSLSPKSPSYNNNEEERLEVVNLSGMALQSLPN-PSL-NLANICKLDLSNNHIKKIPESLTA 97

  Fly    71 NLLNLEILNLSNNQLTELPVSLSSMPKLRILNVSINRLINLPRGFGAFPVLEVLDLSYN------ 129
            .||||..|::.:||:..||.|:..:.||:|||||.|.|::||:.......||.|:.::|
plant    98 RLLNLIALDIHSNQIKALPNSIGCLSKLKILNVSGNFLVSLPQTIQNCRSLEELNANFNELIRLP 162

  Fly   130 ---------------NLNEQV-LPGNFFGMETLRALYLGDNDFEYIPKEVGQLKNLQILGLRDN- 177
                           |.|:.: ||.....:.:||.|....|....:|:::..|.||:||.:..|
plant   163 DNIGLELTNLKKLCVNSNKLISLPATITCLTSLRVLDARLNCLMILPEDLENLINLEILNVSQNF 227

  Fly   178 -DLLELPREVGDLVRLRELHIQNNRLQVLPPEIAQLDLLSNKSVMKMEENPWVNP---IAEQYLL 238
             .|..||..:|.|:.|.||.|..|::.|||..|..:..|...|.   |.||.|:|   :.||.|
plant   228 QYLSALPSSIGLLLNLLELDISYNKITVLPESIGCMRRLRKLSA---EGNPLVSPPIEVVEQSL- 288

  Fly   239 GISHVI-DYL 247
               |.: :||
plant   289 ---HAVREYL 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ics	NP_001285902.1	leucine-rich repeat	29..51	CDD:275380	6/21 (29%)
		leucine-rich repeat	52..84	CDD:275380	13/32 (41%)
		LRR_8	96..156	CDD:290566	23/81 (28%)
		leucine-rich repeat	98..120	CDD:275380	10/21 (48%)
		LRR	119..>222	CDD:227223	35/126 (28%)
		leucine-rich repeat	121..145	CDD:275380	8/45 (18%)
		leucine-rich repeat	146..168	CDD:275380	6/21 (29%)
		leucine-rich repeat	169..191	CDD:275380	9/23 (39%)
PIRL7	NP_194717.2	PRK15370	<48..>300	CDD:185268	83/257 (32%)
		leucine-rich repeat	55..77	CDD:275380	6/23 (26%)
		leucine-rich repeat	78..101	CDD:275380	9/22 (41%)
		leucine-rich repeat	102..124	CDD:275380	7/21 (33%)
		leucine-rich repeat	125..147	CDD:275380	10/21 (48%)
		leucine-rich repeat	148..171	CDD:275380	4/22 (18%)
		leucine-rich repeat	172..194	CDD:275380	4/21 (19%)
		leucine-rich repeat	195..217	CDD:275380	6/21 (29%)
		leucine-rich repeat	218..242	CDD:275380	9/23 (39%)
		leucine-rich repeat	243..265	CDD:275380	9/21 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I2132
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1382533at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.970