DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ics and PIRL8

DIOPT Version :9

Sequence 1:	NP_001285902.1	Gene:	ics / 34774	FlyBaseID:	FBgn0028546	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_194335.2	Gene:	PIRL8 / 828711	AraportID:	AT4G26050	Length:	383	Species:	Arabidopsis thaliana

Alignment Length:	252	Identity:	82/252 - (32%)
Similarity:	123/252 - (48%)	Gaps:	33/252 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 LDLADKGLSSFEELPGLFNMSNITRLTLSHNKISVISPG-IANLLNLEILNLSNNQLTELPVSLS 93
            |||:...|:|..  ....|:::|::|.||:|.|..|... :|.:|||..|:|.:|||..||.|:.
plant    62 LDLSGMSLASLS--ASSINLASISKLDLSNNNIQKIPESLVARMLNLWALDLQSNQLKTLPNSIG 124

  Fly    94 SMPKLRILNVSINRLINLPRGFGAFPVLEVLDLSYN---------------------NLNEQV-L 136
            .:.||:.||||.|.|.:||:.......||.|:.::|                     |.|:.| |
plant   125 CLSKLKFLNVSGNYLQSLPKTIEDCRSLEELNANFNELTRLPDAIGFELTNLTKLSVNSNKLVLL 189

  Fly   137 PGNFFGMETLRALYLGDNDFEYIPKEVGQLKNLQILGLRDN--DLLELPREVGDLVRLRELHIQN 199
            |.:...:.:||.|....|....:|:::..|.|||:|.:..|  .|..||..||.|:.|.||.:..
plant   190 PNSVSYLTSLRVLDARLNRLSSLPEDLENLVNLQVLNVSQNFQHLTTLPYSVGLLISLVELDVSY 254

  Fly   200 NRLQVLPPEIAQLDLLSNKSVMKMEENPWVNP---IAEQYLLGISHVIDYLKTETYK 253
            |.:.|||..:..|..:...||   |.||.::|   :.||.|..:...:....||:||
plant   255 NGITVLPDSLGCLRRIQKLSV---EGNPLISPPFEVVEQGLEALKQYMSEKMTESYK 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ics	NP_001285902.1	leucine-rich repeat	29..51	CDD:275380	6/20 (30%)
		leucine-rich repeat	52..84	CDD:275380	13/32 (41%)
		LRR_8	96..156	CDD:290566	23/81 (28%)
		leucine-rich repeat	98..120	CDD:275380	9/21 (43%)
		LRR	119..>222	CDD:227223	36/126 (29%)
		leucine-rich repeat	121..145	CDD:275380	9/45 (20%)
		leucine-rich repeat	146..168	CDD:275380	6/21 (29%)
		leucine-rich repeat	169..191	CDD:275380	10/23 (43%)
PIRL8	NP_194335.2	PRK15370	<81..>308	CDD:185268	74/229 (32%)
		leucine-rich repeat	84..105	CDD:275380	7/20 (35%)
		leucine-rich repeat	106..128	CDD:275380	9/21 (43%)
		leucine-rich repeat	129..151	CDD:275380	9/21 (43%)
		leucine-rich repeat	152..175	CDD:275380	4/22 (18%)
		leucine-rich repeat	176..198	CDD:275380	5/21 (24%)
		leucine-rich repeat	199..221	CDD:275380	6/21 (29%)
		leucine-rich repeat	222..246	CDD:275380	10/23 (43%)
		leucine-rich repeat	247..269	CDD:275380	8/21 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I2132
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1382533at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.060