DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ics and SPAC926.06c

DIOPT Version :9

Sequence 1:	NP_001285902.1	Gene:	ics / 34774	FlyBaseID:	FBgn0028546	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_594367.1	Gene:	SPAC926.06c / 2543531	PomBaseID:	SPAC926.06c	Length:	621	Species:	Schizosaccharomyces pombe

Alignment Length:	211	Identity:	55/211 - (26%)
Similarity:	92/211 - (43%)	Gaps:	51/211 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 PVSAKMSKAKKVLDE---ARETHNPELDLADKGLSSFEE--LPGLFNMSNITRLTLSHNKISVIS 66
            ||...:|::..||.:   |..:...|...|:...|..|:  :....:.|.:..|..|..|:..|.
pombe   284 PVHKTLSQSVLVLSKDGNASSSGGTENQSANSSSSLMEKDAILSSSSWSQLLYLRCSSCKLKSIP 348

  Fly    67 PGI-ANLLNLEILNLSNNQLTELPVSLSSMPKLRILNVSINRL--------INLPRGFGAFPVLE 122
            ..: .:|.:|..|:||.|:|||:|.:|..:|:|..||::.|::        |:|..       |:
pombe   349 KNVFLSLQSLVSLDLSGNELTEIPYALGELPQLCSLNLASNKITGCRTFYHISLSH-------LQ 406

  Fly   123 VLDLSYNNLNEQVLPGNFFGMETLRALYLGDNDFEYIPKEVGQLKNLQILGLRDN---DLLELPR 184
            :|.||.|:|..  |.|                 .|.:|       :|:.|.:|||   |::|..|
pombe   407 ILVLSRNHLTS--LSG-----------------LENVP-------SLEKLDIRDNSITDVVEFRR 445

  Fly   185 EVGDLVRLRELHIQNN 200
            .||: ....|.::..|
pombe   446 LVGN-TNFEEAYLSLN 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ics	NP_001285902.1	leucine-rich repeat	29..51	CDD:275380	4/23 (17%)
		leucine-rich repeat	52..84	CDD:275380	9/32 (28%)
		LRR_8	96..156	CDD:290566	15/67 (22%)
		leucine-rich repeat	98..120	CDD:275380	6/29 (21%)
		LRR	119..>222	CDD:227223	22/85 (26%)
		leucine-rich repeat	121..145	CDD:275380	8/23 (35%)
		leucine-rich repeat	146..168	CDD:275380	2/21 (10%)
		leucine-rich repeat	169..191	CDD:275380	10/24 (42%)
SPAC926.06c	NP_594367.1	LRR	32..474	CDD:227223	55/211 (26%)
		LRR_RI	<357..>440	CDD:238064	32/115 (28%)
		leucine-rich repeat	358..380	CDD:275380	10/21 (48%)
		leucine-rich repeat	381..404	CDD:275380	6/22 (27%)
		LRR_4	404..444	CDD:289563	17/72 (24%)
		leucine-rich repeat	405..426	CDD:275380	10/46 (22%)
		leucine-rich repeat	427..451	CDD:275380	10/24 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	1	0.960