DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9254 and SLC37A3

DIOPT Version :9

Sequence 1:	NP_609664.1	Gene:	CG9254 / 34773	FlyBaseID:	FBgn0028513	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	NP_996996.1	Gene:	SLC37A3 / 84255	HGNCID:	20651	Length:	494	Species:	Homo sapiens

Alignment Length:	511	Identity:	105/511 - (20%)
Similarity:	183/511 - (35%)	Gaps:	130/511 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 NAYTMRICLSQ-----AITVLVVKRNYTIFHTE---------AICEPDDQSDPSSTFEGGDYDWS 86
            |.:.....|||     .:..|:...:|::.|..         :|.|....|..:::.|.....||
Human     5 NVFQRGSLLSQFSHHHVVVFLLTFFSYSLLHASRKTFSNVKVSISEQWTPSAFNTSVELPVEIWS 69

  Fly    87 Q-------EKQGLILAS----FYIGYIVTHLPGGILADKFGGKWTLSLGIFFTAIFTLLTPVCIV 140
            .       ||..|.|.:    |...|.|.....||:.|:...:|.||.|:..:|:      |..|
Human    70 SNHLFPSAEKATLFLGTLDTIFLFSYAVGLFISGIVGDRLNLRWVLSFGMCSSAL------VVFV 128

  Fly   141 YGGADALI---------VLRVLMGLGEGTTFPALSVLLASWVPANERGMLGALVLGGGQMGSIAG 196
            :|.....:         .|.::.||.:.|.:|.:..::.:|.....||    :|.|.....:..|
Human   129 FGALTEWLRFYNKWLYCCLWIVNGLLQSTGWPCVVAVMGNWFGKAGRG----VVFGLWSACASVG 189

  Fly   197 NIISGYVLSSMDWPWVFYVFAIIALVWFVVFTLVCFSSPFTHPYIKPEE---RAFLAQEVPPPDK 258
            ||:...:.||:......|.|.:.|.|.|....::.|..     .:.|||   ....|:|....|.
Human   190 NILGACLASSVLQYGYEYAFLVTASVQFAGGIVIFFGL-----LVSPEEIGLSGIEAEENFEEDS 249

  Fly   259 NKP----------KTPFFAIL--TSIPMWALIS--------AQIGHDWGF-------YIMVSYLP 296
            ::|          ..|.::|.  :|:.....||        ..|.:...:       |....:||
Human   250 HRPLINGGENEDEYEPNYSIQDDSSVAQVKAISFYQACCLPGVIPYSLAYACLKLVNYSFFFWLP 314

  Fly   297 KYMSDVLRFSIKSNGLYSSLPYVTMW------IMSLLSGCVADQMIKRNCMSTTNTRKIMTGVAA 355
            .|:|:  .|..|.    :....:::|      |...|.|.::|.:.||   :......::..|.:
Human   315 FYLSN--NFGWKE----AEADKLSIWYDVGGIIGGTLQGFISDVLQKR---APVLALSLLLAVGS 370

  Fly   356 FGPAVFMVAASYAGCNRGMVVALFTITMGLMGTYYAGMKLTPLDM-----------------SPN 403
                  ::..|.:..::.:...|.|:|    |.:..|    |.:|                 |..
Human   371 ------LIGYSRSPNDKSINALLMTVT----GFFIGG----PSNMISSAISADLGRQELIQRSSE 421

  Fly   404 YAGTLMAITNGIGAITGVVSPYLVGVMTPNATLLEWRLVFWVAFGVLVVTAIVYCI 459
            ...|:..|.:|.|:|...|..|||.::...   |.|..||:  |.:|:.:..:..|
Human   422 ALATVTGIVDGSGSIGAAVGQYLVSLIRDK---LGWMWVFY--FFILMTSCTIVFI 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9254	NP_609664.1	2A0114euk	28..466	CDD:129972	105/511 (21%)
CG9254	NP_609664.1	MFS	82..461	CDD:119392	94/451 (21%)
SLC37A3	NP_996996.1	UhpC	14..479	CDD:332119	103/502 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148710
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840