DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9254 and slc17a7a

DIOPT Version :9

Sequence 1:	NP_609664.1	Gene:	CG9254 / 34773	FlyBaseID:	FBgn0028513	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	NP_001092225.1	Gene:	slc17a7a / 795293	ZFINID:	ZDB-GENE-050105-5	Length:	582	Species:	Danio rerio

Alignment Length:	483	Identity:	154/483 - (31%)
Similarity:	246/483 - (50%)	Gaps:	30/483 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 EQPEWGIKLSKFFVLPQRWILAIMGFFAIFNAYTMRICLSQAITVLVVKRNYTIFHTEAICEPDD 70
            |:.|..|.....|.||:|:|:||:.......::.:|..|..||..:|  .::|::
Zfish    45 EEKELPIVDCTCFGLPRRYIIAILSGLGFCISFGIRCNLGVAIVSMV--NDHTVY---------- 97

  Fly    71 QSDPSSTFEGGDYDWSQEKQGLILASFYIGYIVTHLPGGILADKFGGKWTLSLGIFFTAIFTLLT 135
             |..........:.|..|..|:|..||:.|||||.:|||.:..||.........|..|:...:|.
Zfish    98 -SGKKPVIVAAQFTWDPETVGMIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAIVATSTLNMLI 161

  Fly   136 PVC--IVYGGADALIVLRVLMGLGEGTTFPALSVLLASWVPANERGMLGALVLGGGQMGSIAGNI 198
            |..  :.||   .:|::||..||.||.::||...:.|.|.|..||..|......|...|::....
Zfish   162 PSAARVHYG---CVIMVRVCQGLVEGVSYPACHGIWAKWAPPLERSRLATTAFCGSYAGAVVAMP 223

  Fly   199 ISGYVLSSMDWPWVFYVFAIIALVWFVVFTLVCFSSPFTHPYIKPEERAFL-------AQEVPPP 256
            ::|.::....|..||||:..:.:.|::.:.||.:.||..||.|.||||.::       |..|.|
Zfish   224 LAGVLVQYTGWSSVFYVYGSVGIFWYLFWILVSYESPAAHPTITPEERKYIEDAIGESAGLVNP- 287

  Fly   257 DKNKPKTPFFAILTSIPMWALISAQIGHDWGFYIMVSYLPKYMSDVLRFSIKSNGLYSSLPYVTM 321
             ..|.|||:....||:|::|:|.|.....|.||:::...|.|..:|..|.|...|:.|:||::.|
Zfish   288 -LQKFKTPWRHFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMVSALPHLVM 351

  Fly   322 WIMSLLSGCVADQMIKRNCMSTTNTRKIMTGVAAFG-PAVFMVAASYAGCNRGMVVALFTITMGL 385
            .|:..:.|.:||.:...|.|:|||.||:| ....|| .|..::...::. .:|:.::...:.:|.
Zfish   352 TIIVPIGGQLADYLRTHNLMTTTNVRKLM-NCGGFGMEATLLLVVGFSH-TKGVAISFLVLAVGF 414

  Fly   386 MGTYYAGMKLTPLDMSPNYAGTLMAITNGIGAITGVVSPYLVGVMTPNATLLEWRLVFWVAFGVL 450
            .|...:|..:..||::|.||..||.|:||:|.::|:|.|.:||.||.:.|..||:.||.:|..|.
Zfish   415 SGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHKTREEWQYVFLIAALVH 479

  Fly   451 VVTAIVYCIWASGDVQPFNDGTNSNKKK 478
            ....|.|.::|||:.||:.|..|::::|
Zfish   480 YGGVIFYGLFASGEKQPWADAENTSEEK 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9254	NP_609664.1	2A0114euk	28..466	CDD:129972	140/447 (31%)
CG9254	NP_609664.1	MFS	82..461	CDD:119392	129/388 (33%)
slc17a7a	NP_001092225.1	2A0114euk	62..501	CDD:129972	146/458 (32%)
slc17a7a	NP_001092225.1	MFS	67..490	CDD:119392	137/442 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582511
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.740