DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9254 and slc17a7

DIOPT Version :9

Sequence 1:	NP_609664.1	Gene:	CG9254 / 34773	FlyBaseID:	FBgn0028513	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	NP_001072608.1	Gene:	slc17a7 / 780064	XenbaseID:	XB-GENE-5742677	Length:	576	Species:	Xenopus tropicalis

Alignment Length:	474	Identity:	148/474 - (31%)
Similarity:	236/474 - (49%)	Gaps:	36/474 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 FVLPQRWILAIMGFFAIFNAYTMRICLSQAITVLVVKRNYTIFHTEAICEPDDQSDPSSTFEGGD 82
            |.||:|:|:|||.......::.:|..|..||..:|  .|.|::....|           ..|...
Frog    57 FGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMV--NNNTVYKGNKI-----------VIEQAQ 108

  Fly    83 YDWSQEKQGLILASFYIGYIVTHLPGGILADKFGGKWTLSLGIFFTAIFTLLTP-------VCIV 140
            :.|..|..|:|..||:.|||||.:|||.:..||.........|..|:...:|.|       .|:
Frog   109 FTWDPETVGMIHGSFFWGYIVTQIPGGYICQKFAANRVFGFAIVATSTLNMLIPSAARVHFACV- 172

  Fly   141 YGGADALIVLRVLMGLGEGTTFPALSVLLASWVPANERGMLGALVLGGGQMGSIAGNIISGYVLS 205
                   |.:|:|.||.||.|:||...:.:.|.|..||..|......|...|::....::|.::.
Frog   173 -------ICVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQ 230

  Fly   206 SMDWPWVFYVFAIIALVWFVVFTLVCFSSPFTHPYIKPEERAFLAQEVPPP-----DKNKPKTPF 265
            ...|..||||:....::|::.:.||.:.||..||.|..||:.::.:.:...     ...|.|.|:
Frog   231 YSGWSSVFYVYGSFGIMWYMFWILVSYESPAIHPTISEEEKKYIEESIGESTGLMNPMAKFKAPW 295

  Fly   266 FAILTSIPMWALISAQIGHDWGFYIMVSYLPKYMSDVLRFSIKSNGLYSSLPYVTMWIMSLLSGC 330
            ....||:|::|:|.|.....|.||:::...|.|..:|..|.|...||.|:||::.|.|:..:.|.
Frog   296 RKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLLSALPHLVMTIIVPIGGQ 360

  Fly   331 VADQMIKRNCMSTTNTRKIMTGVAAFG-PAVFMVAASYAGCNRGMVVALFTITMGLMGTYYAGMK 394
            :||.:..:..|||||.||:| ....|| .|..::...|:. :||:.::...:.:|..|...:|..
Frog   361 IADFLRTKRIMSTTNVRKMM-NCGGFGMEATLLLVVGYSH-SRGVAISFLVLAVGFSGFAISGFN 423

  Fly   395 LTPLDMSPNYAGTLMAITNGIGAITGVVSPYLVGVMTPNATLLEWRLVFWVAFGVLVVTAIVYCI 459
            :..||::|.||..||.|:||:|.::|:|.|.:||.||.:.|..||:.||.:|..|.....:.|.|
Frog   424 VNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHKTREEWQYVFLIASLVHYGGVLFYGI 488

  Fly   460 WASGDVQPFNDGTNSNKKK 478
            :|||:.||:.:...::.:|
Frog   489 FASGEKQPWAEPEETSDEK 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9254	NP_609664.1	2A0114euk	28..466	CDD:129972	139/450 (31%)
CG9254	NP_609664.1	MFS	82..461	CDD:119392	125/391 (32%)
slc17a7	NP_001072608.1	2A0114euk	62..503	CDD:129972	144/463 (31%)
		MFS	67..490	CDD:119392	136/445 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	517..547
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910