Protein Alignment CG9254 and SLC17A6

DIOPT Version :10

• Sequence 1: NP_609664.1
• Gene: CG9254 / 34773
• FlyBaseID: FBgn0028513
• Length: 481
• Species: Drosophila melanogaster
• Sequence 2: NP_065079.1
• Gene: SLC17A6 / 57084
• HGNCID: 16703
• Length: 582
• Species: Homo sapiens
• Alignment Length: 469
• Identity: 149/469 - (31%)
• Similarity: 239/469 - (50%)
• Gaps: 26/469 - (5%)

  Fly    18 FVLPQRWILAIMGFFAIFNAYTMRICLSQAITVLVVKRNYTIFHTEAICEPDDQSDPSSTFEGGD 82
            |.||:|:|:|||.......::.:|..|..||..:|  .|.||.....:.:           |...
Human    65 FGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMV--NNSTIHRGGKVIK-----------EKAK 116

  Fly    83 YDWSQEKQGLILASFYIGYIVTHLPGGILADKFGGKWTLSLGIFFTAIFTLLTPVC--IVYGGAD 145
            ::|..|..|:|..||:.|||:|.:|||.:|.:..........|..|:...:|.|..  :.||
Human   117 FNWDPETVGMIHGSFFWGYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYG--- 178

  Fly   146 ALIVLRVLMGLGEGTTFPALSVLLASWVPANERGMLGALVLGGGQMGSIAGNIISGYVLSSMDWP 210
            .:|.:|:|.||.||.|:||...:.:.|.|..||..|......|...|::....::|.::....|.
Human   179 CVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWS 243

  Fly   211 WVFYVFAIIALVWFVVFTLVCFSSPFTHPYIKPEERAFLAQEVPPPDK-----NKPKTPFFAILT 270
            .||||:....:||::.:.||.:.||..||.|..|||.::.:.:.....     .|.|||:....|
Human   244 SVFYVYGSFGMVWYMFWLLVSYESPAKHPTITDEERRYIEESIGESANLLGAMEKFKTPWRKFFT 308

  Fly   271 SIPMWALISAQIGHDWGFYIMVSYLPKYMSDVLRFSIKSNGLYSSLPYVTMWIMSLLSGCVADQM 335
            |:|::|:|.|.....|.||:::...|.|..:|..|.|...|:.|::|::.|.|:..:.|.:||.:
Human   309 SMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFL 373

  Fly   336 IKRNCMSTTNTRKIMTGVAAFG-PAVFMVAASYAGCNRGMVVALFTITMGLMGTYYAGMKLTPLD 399
            ..:..:|||..|||| ....|| .|..::...|:. .||:.::...:.:|..|...:|..:..||
Human   374 RSKQILSTTTVRKIM-NCGGFGMEATLLLVVGYSH-TRGVAISFLVLAVGFSGFAISGFNVNHLD 436

  Fly   400 MSPNYAGTLMAITNGIGAITGVVSPYLVGVMTPNATLLEWRLVFWVAFGVLVVTAIVYCIWASGD 464
            ::|.||..||.|:||:|.::|:|.|.:||.||.|.:..||:.||.:|..|.....|.|.|:|||:
Human   437 IAPRYASILMGISNGVGTLSGMVCPIIVGAMTKNKSREEWQYVFLIAALVHYGGVIFYAIFASGE 501

  Fly   465 VQPFNDGTNSNKKK 478
            .||:.|...::::|
Human   502 KQPWADPEETSEEK 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9254	NP_609664.1	MFS_SLC17	27..461	CDD:340876	137/441 (31%)
SLC17A6	NP_065079.1	MFS_SLC17A6_7_8_VGluT	74..498	CDD:340940	137/441 (31%)