DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9254 and slc17a8

DIOPT Version :9

Sequence 1:	NP_609664.1	Gene:	CG9254 / 34773	FlyBaseID:	FBgn0028513	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	NP_001076304.1	Gene:	slc17a8 / 563467	ZFINID:	ZDB-GENE-060503-416	Length:	590	Species:	Danio rerio

Alignment Length:	469	Identity:	145/469 - (30%)
Similarity:	244/469 - (52%)	Gaps:	26/469 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 FVLPQRWILAIMGFFAIFNAYTMRICLSQAITVLVVKRNYTIFHTEAICEPDDQSDPSSTFEGGD 82
            |.||:|:|:|::.......::.:|..|..|| |.:|..|....:..|:.:|            ..
Zfish    70 FGLPKRYIIAMLSGLGFCISFGIRCNLGVAI-VEMVNNNTVYINGTAVMQP------------AQ 121

  Fly    83 YDWSQEKQGLILASFYIGYIVTHLPGGILADKFGGKWTLSLGIFFTAIFTLLTPVC--IVYGGAD 145
            ::|..|..|||..||:.|||||.:|||.:::|..........||.|::..:..|..  :.||
Zfish   122 FNWDPETVGLIHGSFFWGYIVTQIPGGFISNKLAANRVFGAAIFLTSVLNMFIPSAARVHYG--- 183

  Fly   146 ALIVLRVLMGLGEGTTFPALSVLLASWVPANERGMLGALVLGGGQMGSIAGNIISGYVLSSMDWP 210
            .::.:|:|.||.||.|:||...:.:.|.|..||..|......|...|::....::|.::..:.||
Zfish   184 CVMFVRILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYVGWP 248

  Fly   211 WVFYVFAIIALVWFVVFTLVCFSSPFTHPYIKPEERAFLAQEVPP-----PDKNKPKTPFFAILT 270
            .|||::.:..::|::.:.|:.::||..||.|..|||.::...:..     ....|.|||:....|
Zfish   249 SVFYIYGVFGIIWYIFWILLAYNSPAVHPTISEEERNYIETSIGEGANLMSSTEKFKTPWREFFT 313

  Fly   271 SIPMWALISAQIGHDWGFYIMVSYLPKYMSDVLRFSIKSNGLYSSLPYVTMWIMSLLSGCVADQM 335
            |:|::|:|.|.....|.||:::...|.|..:|..|.|...|:.|::|::.|.|:..:.|.:||.:
Zfish   314 SMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFPISKVGILSAVPHMVMTIIVPIGGQLADFL 378

  Fly   336 IKRNCMSTTNTRKIMTGVAAFG-PAVFMVAASYAGCNRGMVVALFTITMGLMGTYYAGMKLTPLD 399
            ..|..:|||..|||| ....|| .|..::...::. .|.:.::...:.:|..|...:|..:..||
Zfish   379 RSRKILSTTTVRKIM-NCGGFGMEATLLLVVGFSH-TRAVAISFLILAVGFSGFAISGFNVNHLD 441

  Fly   400 MSPNYAGTLMAITNGIGAITGVVSPYLVGVMTPNATLLEWRLVFWVAFGVLVVTAIVYCIWASGD 464
            ::|.||..||.|:||:|.::|:|.|.:||.:|.:.|.|||:.||.:|..|.....|.|.|:|||:
Zfish   442 IAPRYASILMGISNGVGTLSGMVCPLIVGALTKHKTRLEWQHVFVIASMVHYTGVIFYAIFASGE 506

  Fly   465 VQPFNDGTNSNKKK 478
            .|.:.|..|::.:|
Zfish   507 KQDWADPENTSDEK 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9254	NP_609664.1	2A0114euk	28..466	CDD:129972	135/445 (30%)
CG9254	NP_609664.1	MFS	82..461	CDD:119392	123/386 (32%)
slc17a8	NP_001076304.1	2A0114euk	75..514	CDD:129972	140/456 (31%)
		MFS	81..503	CDD:119392	132/439 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	526..590
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582533
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.740