DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9254 and MFS14

DIOPT Version :9

Sequence 1:	NP_609664.1	Gene:	CG9254 / 34773	FlyBaseID:	FBgn0028513	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	NP_001286591.1	Gene:	MFS14 / 46085	FlyBaseID:	FBgn0010651	Length:	497	Species:	Drosophila melanogaster

Alignment Length:	477	Identity:	155/477 - (32%)
Similarity:	257/477 - (53%)	Gaps:	27/477 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 KFFVLPQRWILAIMGFFAIFNAYTMRICLSQAITVLV-----VKRNYTIFHTEAICEPDDQSDPS 75
            |||.:  |.:..|:.||.:..:|..|:.||.|:..:.     :.:|    :|.....|   |:|.
  Fly    18 KFFGV--RHVQCILCFFCLAMSYAWRVNLSVALVAMTDNSTSLAQN----NTNTGVAP---SEPG 73

  Fly    76 STFEGGD--YDWSQEKQGLILASFYIGYIVTHLPGGILADKFGGKWTLSLGIFFTAIFTLLTPVC 138
            ..|...:  |:::|:::|.:.|||:.|||||.:|||.:|.::|.|..|..|:...|:.|:|:|:.
  Fly    74 FDFFNSERYYNFTQKEKGNLQASFFFGYIVTQVPGGYIAQRYGAKTMLMYGLGIAALITMLSPMS 138

  Fly   139 IVYGGADALIVLRVLMGLGEGTTFPALSVLLASWVPANERGMLGALVLGGGQMGSIAGNIISGYV 203
            :.:|.. ||.|:|.:|||.:|...||...|||.|.||:||||||.|...|.|.|::.....||::
  Fly   139 LQFGWV-ALAVMRFVMGLAQGAVHPATHALLAKWSPADERGMLGTLCYSGAQFGTVVMLATSGFI 202

  Fly   204 LSS-MDWPWVFYVFAIIALVWFVVFTLVCFSSPFTHPYIKPEERAFLAQ-----EVPPPDKNKPK 262
            ..| :.||.:||:......:|.|.:.|...|:|..|..|.|.|..::..     ::...:|..|
  Fly   203 ADSVLGWPSIFYLGGACGFIWMVFWYLFSASTPEEHRLISPGELKYITDSRSDGKMQSAEKLAP- 266

  Fly   263 TPFFAILTSIPMWALISAQIGHDWGFYIMVSYLPKYMSDVLRFSIKSNGLYSSLPYVTMWIMSLL 327
            ||:.||.:|:|..:|:.....|.:|:::::..:|.||..:....||...|.|||||:.|.::|..
  Fly   267 TPWKAIFSSLPFLSLLVVHCTHIFGYWLLLMQIPTYMKKIYHVDIKKGALLSSLPYMVMLLLSFF 331

  Fly   328 SGCVADQMIKRNCMSTTNTRKIMTGVAAFGPAVFMVAASYAGC-NRGMVVALFTITMGLMGTYYA 391
            ...::..:.|:..||.:..|||...:..:.|.:.::|..|... |..:.|.|.|:|:|:.|..|.
  Fly   332 FVWLSKVLQKKEGMSLSFNRKIFNSIGHWIPMLSLIALGYVPADNAPLAVTLLTLTVGISGATYL 396

  Fly   392 GMKLTPLDMSPNYAGTLMAITNGIGAITGVVSPYLVG-VMTPNATLLEWRLVFWVAFGVLVVTAI 455
            |.::..:|:|||||||||.|||....:...::|.:|| ::....::.||||||.:|.....:..:
  Fly   397 GFQVNHIDLSPNYAGTLMGITNCAANVMSGIAPVIVGQIVVDETSVTEWRLVFLLAAAFYFLGNL 461

  Fly   456 VYCIWASGDVQPFNDGTNSNKK 477
            ::.|:...:|| :.|....||:
  Fly   462 LFVIFGRTEVQ-WWDSPRDNKE 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9254	NP_609664.1	2A0114euk	28..466	CDD:129972	146/452 (32%)
CG9254	NP_609664.1	MFS	82..461	CDD:119392	132/388 (34%)
MFS14	NP_001286591.1	2A0114euk	19..477	CDD:129972	152/469 (32%)
MFS14	NP_001286591.1	MFS	81..466	CDD:119392	131/386 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451924
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	9	8.890