DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9254 and MFS3

DIOPT Version :9

Sequence 1:	NP_609664.1	Gene:	CG9254 / 34773	FlyBaseID:	FBgn0028513	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	NP_608572.1	Gene:	MFS3 / 33292	FlyBaseID:	FBgn0031307	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	498	Identity:	150/498 - (30%)
Similarity:	259/498 - (52%)	Gaps:	39/498 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MADAKEQPEWGIKLSKFFVLPQRWILAIMGFFAIFNAYTMRICLSQAITVLVVKRNYTIF----- 60
            |.|  |.|..|..|.|  ::|.|::||::|...:...|.:::.||.|:..:|   |:|..
  Fly     1 MTD--EVPAKGSILGK--LVPARYVLALLGSIGMAIVYGLKVNLSVAMVAMV---NHTAIKAHGD 58

  Fly    61 ------HTEAI------------CE-PDDQSDPSSTFEGGDYDWSQEKQGLILASFYIGYIVTHL 106
                  |...|            |. |...|:.::..|.|.:|||:..||.:|:.::.||:|:.:
  Fly    59 GGGHGGHGSVILSNASQVSLVEECNPPGGASNVTAKVEDGPFDWSEPLQGTLLSCYFWGYLVSQI 123

  Fly   107 PGGILADKFGGKWTLSLGIFFTAIFTLLTPVC--IVYGGADALIVLRVLMGLGEGTTFPALSVLL 169
            |...:|:.|..||.:...:....:.||||||.  :.|||   ||::|||.|:|.|.:|||:.|::
  Fly   124 PLAHVAENFSAKWVMLFSVAINVVCTLLTPVFTELHYGG---LILMRVLEGVGGGASFPAMHVMI 185

  Fly   170 ASWVPANERGMLGALVLGGGQMGSIAGNIISGYVLSSMDWPWVFYVFAIIALVWFVVFTLVCFSS 234
            |||.|..||.::..::..|...|:....:::|...:...|..||||...::.:|.:::.::...:
  Fly   186 ASWAPPTERMVMSTIIYVGTSAGTALSILLAGVCSAQWGWESVFYVMGALSCIWMLLWVILVQDN 250

  Fly   235 PFTHPYIKPEERAFLAQEVPPPDKNK--PKTPFFAILTSIPMWALISAQIGHDWGFYIMVSYLPK 297
            |....:|..|||..:...:....|.:  |..|:..:.||:|.||::.|....::|:|:.:..:|.
  Fly   251 PNKQRFISLEERQMITSSLGTEQKTEHHPAVPWGKVFTSVPFWAILIAHTCSNFGWYMFLIEIPF 315

  Fly   298 YMSDVLRFSIKSNGLYSSLPYVTMWIMSLLSGCVADQMIKRNCMSTTNTRKIMTGVAAFGPAVFM 362
            ||..||:|::.||...|:|||..|.|.|:..|.:.|.:..:..::||..||..|.:....|.|.:
  Fly   316 YMKQVLKFNVASNAALSALPYFPMIIFSICLGKLLDSLQAKGKITTTVARKTATSICTLIPGVCL 380

  Fly   363 VAASYAGCNRGMVVALFTITMGLMGTYYAGMKLTPLDMSPNYAGTLMAITNGIGAITGVVSPYLV 427
            :...|.||.....|::.::.:..||:.::|.....:|::||:||||:|:||....:.|:|.|..|
  Fly   381 LVLCYIGCRHYEAVSVMSVGIVAMGSMFSGFLSNHIDIAPNFAGTLVALTNTAATLPGIVVPLFV 445

  Fly   428 GVMTP-NATLLEWRLVFWVAFGVLVVTAIVYCIWASGDVQPFN 469
            |.:|. |..:..||::|.|...:..:..:|:....||..||:|
  Fly   446 GFVTKGNQNIGAWRIIFGVTIVLFALEFLVFVFLGSGSEQPWN 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9254	NP_609664.1	2A0114euk	28..466	CDD:129972	136/466 (29%)
CG9254	NP_609664.1	MFS	82..461	CDD:119392	119/383 (31%)
MFS3	NP_608572.1	2A0114euk	19..489	CDD:129972	142/476 (30%)
MFS3	NP_608572.1	MFS	100..479	CDD:119392	119/381 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	8	7.960