DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9254 and SPAC1002.16c

DIOPT Version :9

Sequence 1:	NP_609664.1	Gene:	CG9254 / 34773	FlyBaseID:	FBgn0028513	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	NP_593504.1	Gene:	SPAC1002.16c / 2543262	PomBaseID:	SPAC1002.16c	Length:	499	Species:	Schizosaccharomyces pombe

Alignment Length:	468	Identity:	96/468 - (20%)
Similarity:	179/468 - (38%)	Gaps:	78/468 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 KRNYTIFHTEAICEPD----------DQSDPSSTFEGG---DYDWSQEKQGLILASFYIGYIVTH 105
            :|:..:|..:.:..|.          |:|:..:....|   |.....::..:|.:.||:.:|:..
pombe    47 ERDSLLFRLDLVLAPTIMILYLVAFLDRSNIGNAKVAGLPEDLKLKGDQFNIIASVFYVTFILFE 111

  Fly   106 LPGGILADKFGGKWTLSLGIFFTAIFTLLTPVCIVYGGADALIVLRVLMGLGEGTTFPALSVLLA 170
            :|..:|..|...|..|:..:...::.|:.|..|..:||   |:..|:::|..|...||.|::.|.
pombe   112 MPTTLLMKKVQPKRMLAFIVISYSLTTIFTGFCHNFGG---LLAARLVLGFCEAGLFPCLALYLT 173

  Fly   171 SWVPANERGMLGALVLGGGQMGSIAGNIISGYVLSSMD-------WPWVFYVFAIIAL-----VW 223
            ......|.....|.:.....:....|.:.: |.:..||       |.|:|.:..:|..     |:
pombe   174 MIYSRVELAPRIAYLFASSALSGAFGGLFA-YAVLHMDGVGGFAGWRWLFIIEGLIGFVCGVAVY 237

  Fly   224 FVV---FTLVCFSSPFTHPYIKPEERAFLAQEVPPP--DKNKPKTPFFAILTSIPMWALISAQIG 283
            |::   .|...|.|. ||..:..:.:...|.::...  |....|:.|    |...::....::.|
pombe   238 FIIPNDITKAWFLSK-THQEMMRKRQLERAADLEAAHFDWKGVKSAF----TDFKVYLYALSEFG 297

  Fly   284 HDWGFYIMVSYLPKYMSDVLRFSIKSNGLYSSLPYVT--MWIMSLLSGCVADQMIKRNCMSTTNT 346
            .|...|...::||..:|.:...|:       |:.|:|  ::|:...:...|..:..|     .:.
pombe   298 QDTCLYGFSTFLPAIISGMGYTSL-------SVQYMTIPVYILGAATYIAASFLSDR-----FHH 350

  Fly   347 RKIMTGVAAFGPAVFMVAASYAGCNRGMVVALFTITMGLMGTYY-AGMKLTPL--DMSPNY---- 404
            |.|:..:....|.|..:.  ...|.....|..|...:..:|.|. ||:.:|.|  :::|:|
pombe   351 RGIILIIGNIFPIVGYIL--LLACQNNKSVLYFACYLCSVGVYTGAGLNVTWLSANIAPHYKRAT 413

  Fly   405 -AGTLMAITNGIGAITGVVSPYLVGVMTPNATLLEWRLVFWVAFGVLVVTAIVYCIWASGDVQPF 468
             ....:||.|..|.:.|.:..|....:..:.|.|       :|..:..|..:|...        |
pombe   414 AISLQLAIANSSGILAGQIYRYPPKYIAGHLTSL-------IAIFISTVLHVVNIF--------F 463

  Fly   469 NDGTNSNKKKDAA 481
            ....||.|:|..|
pombe   464 LKHQNSKKQKSLA 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9254	NP_609664.1	2A0114euk	28..466	CDD:129972	90/451 (20%)
CG9254	NP_609664.1	MFS	82..461	CDD:119392	84/405 (21%)
SPAC1002.16c	NP_593504.1	MFS	63..455	CDD:119392	85/421 (20%)
SPAC1002.16c	NP_593504.1	2A0114	65..435	CDD:273326	81/392 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050