DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9254 and SPCPB1C11.03

DIOPT Version :9

Sequence 1:	NP_609664.1	Gene:	CG9254 / 34773	FlyBaseID:	FBgn0028513	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	NP_001342988.1	Gene:	SPCPB1C11.03 / 2539453	PomBaseID:	SPCPB1C11.03	Length:	570	Species:	Schizosaccharomyces pombe

Alignment Length:	494	Identity:	103/494 - (20%)
Similarity:	177/494 - (35%)	Gaps:	121/494 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MADAKE----QPEWGIKLS-KFFVLPQRWILAIMGFFAIFNAYTMRICLSQAITVLVVKRNYTIF 60
            |.|||:    .|:...||. |.::    ::|.::||.      .|.:.:.:|          |:.
pombe    77 MQDAKKLDPLTPKQESKLKWKLYI----YLLLMLGFL------DMMLFIGKA----------TLS 121

  Fly    61 HTEAICEPDDQSDPSSTFEGGDYDWSQEKQGLILASFYIGYIVTHLPGGILADKFG-GKWTLSLG 124
            ::..:...||....|:.:..            :...||:||||...||..:...|. ||: :.|.
pombe   122 YSTILGLFDDVHITSNQYNN------------LNTLFYVGYIVGQFPGHYIMQTFPLGKF-VGLV 173

  Fly   125 IFFTAIFTLLTPVCIVYGGADALIVLRVLMGLGEGTTFPALSVLLASWVPANERGMLGALVLGGG 189
            .|..::...|......|||   ||.||..:|..|....||:...:..:....|:..|..:.
pombe   174 TFSWSVIVFLHCCAYNYGG---LIALRFFLGFTESCLLPAMEATMGMFFTHQEQAFLQPVF---- 231

  Fly   190 QMGSIAGNIISGYVLSSMDW------PWVFYVFAIIALVWFVVFTLVCF--SSPFTHPYIKPEER 246
            .:..::..|.:|::...:::      ||..::.....:.:|:...|..:  .:|....::..||:
pombe   232 WISCLSCGIPAGFIAYGLEFVTKSIAPWKLFMIITGGITFFLSIFLFFYYPDNPSKARFLTDEEK 296

  Fly   247 AFLAQEVPPPDK----NK--PKTPFFAILTSIPMWALISAQIGHDWGFYIMVSYLPKYMSDVLRF 305
            .:....|....:    ||  .|..|...|.....|....|      .|.:|:|....|..:::..
pombe   297 LYTIDRVRKSTRGGIENKIFKKHQFIEALKDPITWLFTFA------AFTLMLSNNLAYQQNLIFT 355

  Fly   306 SIKSNGLYSSLPYVTMWIMSLLSGCVADQMIKRNCMSTTNTRKIMTGVAAFG----PAVFMVAAS 366
            |:..:.|.|:|                                  .|||..|    .|:....|.
pombe   356 SLNVSDLNSTL----------------------------------VGVALAGYNTVSAIIATFAM 386

  Fly   367 YAGCNRGMVVALFTITMGLMGTYYAGMKLTPLDMSPNYAGTL--MAITNGIGAITGVVSPYLVGV 429
            |...|:....|:|.:...:.|    |:....|..| |..|.|  |.|.:..| ||.:::   :|.
pombe   387 YLIPNQSAYHAMFWMLPSITG----GIAFVALPWS-NRIGELATMIIASDFG-ITYIIA---LGW 442

  Fly   430 MTPNAT----LLEWRLVFWVAFGVLVVTAIVYCIWASGD 464
            .|..:|    .|...|:|.|  |..:...|...:|.|.|
pombe   443 TTATSTGYTKKLTRGLMFMV--GYAIANIISPQLWQSRD 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9254	NP_609664.1	2A0114euk	28..466	CDD:129972	94/462 (20%)
CG9254	NP_609664.1	MFS	82..461	CDD:119392	83/403 (21%)
SPCPB1C11.03	NP_001342988.1	UhpC	102..494	CDD:332119	95/465 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050