DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9254 and slc-17.7

DIOPT Version :9

Sequence 1:	NP_609664.1	Gene:	CG9254 / 34773	FlyBaseID:	FBgn0028513	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	NP_505399.1	Gene:	slc-17.7 / 179308	WormBaseID:	WBGene00022788	Length:	506	Species:	Caenorhabditis elegans

Alignment Length:	456	Identity:	119/456 - (26%)
Similarity:	210/456 - (46%)	Gaps:	25/456 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 ICL--SQAIT---VLVVKRNYTIFHTEAICEPDDQSDPSSTFE-GGDYDWSQEKQGLILASFYIG 100
            :|:  |.|:|   .::...|.:|.....:| |..|...|...| .|...|:.:.:.:|.|:||.|
Worm    40 VCMLNSTALTDGKPMIASLNTSIEPATPLC-PLLQFGESKVVEHKGTIFWTSQDRAIIFAAFYAG 103

  Fly   101 YIVTHLPGGILADKFGGKWTLSLGIFFTAIFTLLTPVCI--VYGGADALIVLRVLMGLGEGTTFP 163
            .:|..|...:|....|...::..|.....:.|.|||...  ...|...:|:||.:||.|:|..:|
Worm   104 GLVATLASEVLNRYIGATRSVLYGGIANVVGTFLTPFVASQTNFGTFPIILLRFVMGFGQGVLWP 168

  Fly   164 ALSVLLASWVPANERGMLGALVLGGGQMGSIAGNIISGYVLSSM-----DWPWVFYVFAIIALVW 223
            .:.||:|.|.|.||:....|:...|.|:..    :|:.:..:.:     .||..|:|:|:..:|.
Worm   169 CMLVLIAQWFPVNEKSTALAIATTGNQLSV----VIAMFATAELCQLPWGWPMAFHVYAVCGIVM 229

  Fly   224 FVVFTLVCFSSP-FTHPYIKPEERAFLAQEVPPPDKNKPKTP-FFAILTSIPMWALISAQIGHDW 286
            .:::.::.:.|| .....:..:|..::..|   ..:.:|:.| :.|::.|..:||:.::...|::
Worm   230 CIIWYMMVYDSPCHADKKLSRDELHYITTE---RVRLRPQHPNWMALMKSPVVWAIAASSFAHNY 291

  Fly   287 GFYIMVSYLPKYMSDVLRFSIKSNGLYSSLPYVTMWIMSLLSGCVADQMIKRNCMSTTNTRKIMT 351
            .....::|||.|...||..|:.||||:|:||:|...|..:....:|:...||:........|...
Worm   292 VTVGTITYLPLYYKTVLNMSLTSNGLWSALPFVLQLISKVFYAGMAESARKRDWSDINRITKFCN 356

  Fly   352 GVAAFGPAVFMVAASYAGCN-RGMVVALFTITMGLMGTYYAGMKLTPLDMSPNYAGTLMAITNGI 415
            ..|:||.|:.........|: ||..:.|..:.|..:..|..|...:.:.::|.....:.|.:...
Worm   357 SSASFGIAICFGLLCLCDCSQRGAAIFLICLAMCFVSGYIPGYNTSAVTIAPGQTAAIAAFSRFW 421

  Fly   416 GAITGVVSPYLVGVMTPNATLLEWRLVFWVAFGVLVVTAIVYCIWASGDVQPFNDGTNSNKKKDA 480
            |.|...|:||.:|..|...|..||::||.|...:.|||.|.:....:..:|.: |.|:|....:.
Worm   422 GQIASSVAPYHIGAYTKQGTADEWKIVFAVIAAICVVTGIFFQCCGTASLQDW-DSTHSKAPIEV 485

  Fly   481 A 481
            |
Worm   486 A 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9254	NP_609664.1	2A0114euk	28..466	CDD:129972	114/439 (26%)
CG9254	NP_609664.1	MFS	82..461	CDD:119392	102/388 (26%)
slc-17.7	NP_505399.1	MFS	31..467	CDD:391944	114/434 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28615
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.920