DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9254 and Y19D10A.4

DIOPT Version :9

Sequence 1:	NP_609664.1	Gene:	CG9254 / 34773	FlyBaseID:	FBgn0028513	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	NP_503657.2	Gene:	Y19D10A.4 / 178718	WormBaseID:	WBGene00021219	Length:	475	Species:	Caenorhabditis elegans

Alignment Length:	500	Identity:	113/500 - (22%)
Similarity:	207/500 - (41%)	Gaps:	84/500 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 SKFFVLPQRWILAIMGFFAIFNAYTMRICLSQAITVLVVKRNYTIFHTEAICEPD---DQSDPSS 76
            |..|..|||.|    ..|..:|...:.|.:.....:.:.:.|..||....||..|   :|...:.
Worm    18 SDIFETPQRKI----SNFVFWNQTRVFILILSLTCMTLTQINSQIFTFTVICMDDLIVEQQTSNL 78

  Fly    77 TFEGGDYDWSQ--EKQGLILASFYIGYIVTHLPGGILADKFGGKWTLSLGIFFTAIFTLLTPVCI 139
            |    :..|.:  .::.::.::..||.:|..:|...:.:..|.:.|||.....:.:.|..||:.:
Worm    79 T----EPHWIEGTTEKSILFSATAIGALVALIPSVPILNSLGVRLTLSFCGLCSTLGTFFTPLAV 139

  Fly   140 VYGGADALIVL-RVLMGLGEGTTFPALSVLLASWVPANERGMLGALVLGGGQMGSIAGNIISGYV 203
            .|  :..|:|. |||.|:|.......|.|:.:.|.|..|.....|::....|..::....|||.:
Worm   140 TY--SFYLVVFCRVLQGIGISVILTVLGVIPSYWSPKTEYSTYLAILSCAWQFSNVIFMPISGIL 202

  Fly   204 L-SSMDWPWVFYVFAIIALVWFVVFTLVCFSSPFTHPYIKPEERAFLAQEVPPPDKNKPKTPFFA 267
            . ||..|..::|||.:....::.||.:.....|..|..:..:|   |.|.|    :.||:   ..
Worm   203 CDSSFGWRSIYYVFGVATGFFYFVFFMFYTDIPGIHKNVSEKE---LGQIV----EGKPE---HT 257

  Fly   268 ILTSIPMW------ALISAQI---GHDWGFYIMVSYLPKYMSDVLRFSIKSNGLYSSLPYVTMWI 323
            :..::|.|      .::||.:   |.:.||..::.|.|.|:.:||:|.::|.|..::|||....|
Worm   258 VREAVPYWKICTDRCVLSAWVSFLGGNLGFITLLLYGPTYLREVLQFDVRSTGYINALPYALCAI 322

  Fly   324 MSLLSGCVADQMIKRNCMSTTNTRKIMTGVAAFGPAVFMVAASYAGCNRGMVVALFT-------- 380
            ....:|.::|:      ::..:.:.|.|         |.:.:|..|...|.::..:|
Worm   323 YKFGAGKISDR------VTFASDKAIYT---------FWLFSSIIGLGIGYIIMAWTSDRNVAFV 372

  Fly   381 ------ITMGLMGTYYAGMKLTPLDMSPNYAGTLMAITNGIGAITGVVSPYLVGVMTPNATLLEW 439
                  :|.||:  ..|.:|...:....:....:.|| :.:......:||..||::.|:.|..:|
Worm   373 AFAFAVVTSGLI--IMACVKCLAMRCQQHCHFAVSAI-SFLSYCVQFISPLGVGILCPDNTPDQW 434

  Fly   440 RLVFWVAFGVLVVTAIVYCIWASGDVQPF-----NDGTNSNKKKD 479
            ..:|.:...::::|.           .||     ....|..|:||
Worm   435 SRLFIIITLIMIITN-----------APFPWLTTQQAANYTKRKD 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9254	NP_609664.1	2A0114euk	28..466	CDD:129972	101/467 (22%)
CG9254	NP_609664.1	MFS	82..461	CDD:119392	90/405 (22%)
Y19D10A.4	NP_503657.2	MFS	89..>332	CDD:391944	65/254 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160226
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740