DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9254 and T11G6.2

DIOPT Version :9

Sequence 1:	NP_609664.1	Gene:	CG9254 / 34773	FlyBaseID:	FBgn0028513	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	NP_001076702.1	Gene:	T11G6.2 / 177977	WormBaseID:	WBGene00011717	Length:	502	Species:	Caenorhabditis elegans

Alignment Length:	504	Identity:	104/504 - (20%)
Similarity:	187/504 - (37%)	Gaps:	115/504 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 IKLSKFF--VLPQRWIL-AIMGFFAIFNAYTMRICLSQAITVLVVKRNYTIFHT--EAICEPDDQ 71
            :..|.|:  :..|:|.. .:..|...|.:|.|.....:  |:..||.  ::.||  .....||..
Worm    17 VSSSSFWTRITGQKWSKHHVFIFVHTFMSYAMLHATRK--TLSTVKP--SLIHTWISNTSTPDGP 77

  Fly    72 SDPSSTFEGGDYDWSQEKQGLILASFYIGYIVTHLPGGILADKFGGKWTLSLGIFFTAI----FT 132
            ..||.       ..:.|..|::...|.:.|.:.....|||.|.:..:..|:.|:..::|    |.
Worm    78 VFPSQ-------QAAAEFLGVLDTGFLVAYAIGLYICGILGDNYNPRRLLTAGMMLSSIIVFCFG 135

  Fly   133 LLTPVC-----IVYGGADALIVLRVLMGLGEGTTFPALSVLLASWVPANERGMLGALVLGGGQMG 192
            .||...     :||.      .|.:|.|..:...:|....::.:|...|.||.:.........:|
Worm   136 YLTETFHFYSPMVYS------FLWILNGFIQSVGWPVEVSIMGNWFGHNARGAVMGAWSSCASVG 194

  Fly   193 SIAGNIISGYVLSSMDWPWVF----YVFAIIALVWFVVFTLVCFSSPFTHPY-----IKPEERAF 248
            :|.|.:|:.|.|        |    |.|.|...:.|:...||.|..| :.|:     |.||:
Worm   195 NIIGTLIASYTL--------FLGYQYSFLIACSLLFIYSFLVFFQLP-SAPWEVSSDILPEQ--- 247

  Fly   249 LAQEVPPPDKNKPKTPFFAILTSIPMWALISAQIGH------DWGFYIMVSYLPKYMSDVLRFSI 307
             .:|....|:...:.|....|.:..:..:|:..:.:      ::||:.   :||.|:
Worm   248 -MEEEETDDEPTERPPPIGFLKAWLLPGVIAYSLAYACLKLVNYGFFF---WLPYYL-------- 300

  Fly   308 KSNGLYSSLPY---VTMW------IMSLLSGCVADQMIKRN-------CMSTTNTRKIMTGVAAF 356
             ..||:....|   ::.|      :.::|:|..:|.|..|.       .|:|     :...:.|.
Worm   301 -HAGLHWPESYADSLSTWYDVGGIVAAVLAGAFSDHMRSRTPVVFIMLLMAT-----VSLYIYAH 359

  Fly   357 GPA-------VFMVAASYAGCNRGMVVALFTITMGLMGTYYAGMKLTPLDMSPNYAGTLMAITNG 414
            .|.       :.:||..:.|....|:.:..|..:|         |...|..:.....|:..|.:|
Worm   360 SPESYNWNAFLLLVAGFFIGGPANMISSSITADLG---------KCDQLRGNAEALSTVTGIIDG 415

  Fly   415 IGAITGVVSPYLVGVMTPNAT-LLEWRLVFWVAFGVLVVTA--IVYCIW 460
            .|:|...:..:.:    |:.. ...|..||:....:::.||  :|..:|
Worm   416 TGSIGAAIGQWFI----PSVQHWFGWDAVFYGFIVMILCTALCLVPVLW 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9254	NP_609664.1	2A0114euk	28..466	CDD:129972	100/485 (21%)
CG9254	NP_609664.1	MFS	82..461	CDD:119392	87/429 (20%)
T11G6.2	NP_001076702.1	MFS_SLC37A3	35..459	CDD:340900	99/483 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160261
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840