DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9254 and Slc17a7

DIOPT Version :9

Sequence 1:	NP_609664.1	Gene:	CG9254 / 34773	FlyBaseID:	FBgn0028513	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	XP_038966881.1	Gene:	Slc17a7 / 116638	RGDID:	620101	Length:	585	Species:	Rattus norvegicus

Alignment Length:	486	Identity:	155/486 - (31%)
Similarity:	243/486 - (50%)	Gaps:	35/486 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 FVLPQRWILAIMGFFAIFNAYTMRICLSQAITVL------------VVKRNYTIFHTEAICEPDD 70
            |.||:|:|:|||.......::.:|..|..||..:            ||:..|...|.:....|
  Rat    57 FGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTTHRGGHVVVQTPYRSVHKQEAVTP-- 119

  Fly    71 QSDPSSTFEGGD-----YDWSQEKQGLILASFYIGYIVTHLPGGILADKFGGKWTLSLGIFFTAI 130
               .....:|||     ::|..|..|||..||:.|||||.:|||.:..||.........|..|:.
  Rat   120 ---TVGDIQGGDTEKAQFNWDPETVGLIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAIVATST 181

  Fly   131 FTLLTPVC--IVYGGADALIVLRVLMGLGEGTTFPALSVLLASWVPANERGMLGALVLGGGQMGS 193
            ..:|.|..  :.||   .:|.:|:|.||.||.|:||...:.:.|.|..||..|......|...|:
  Rat   182 LNMLIPSAARVHYG---CVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGA 243

  Fly   194 IAGNIISGYVLSSMDWPWVFYVFAIIALVWFVVFTLVCFSSPFTHPYIKPEERAFLAQEVPPPDK 258
            :....::|.::....|..||||:....:.|::.:.||.:.||..||.|..|||.::...:....|
  Rat   244 VVAMPLAGVLVQYSGWSSVFYVYGSFGIFWYLFWLLVSYESPALHPSISEEERKYIEDAIGESAK 308

  Fly   259 -----NKPKTPFFAILTSIPMWALISAQIGHDWGFYIMVSYLPKYMSDVLRFSIKSNGLYSSLPY 318
                 .|..||:....||:|::|:|.|.....|.||:::...|.|..:|..|.|...||.|:||:
  Rat   309 LMNPVTKFNTPWRRFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLVSALPH 373

  Fly   319 VTMWIMSLLSGCVADQMIKRNCMSTTNTRKIMTGVAAFG-PAVFMVAASYAGCNRGMVVALFTIT 382
            :.|.|:..:.|.:||.:..|:.|||||.||:| ....|| .|..::...|:. ::|:.::...:.
  Rat   374 LVMTIIVPIGGQIADFLRSRHIMSTTNVRKLM-NCGGFGMEATLLLVVGYSH-SKGVAISFLVLA 436

  Fly   383 MGLMGTYYAGMKLTPLDMSPNYAGTLMAITNGIGAITGVVSPYLVGVMTPNATLLEWRLVFWVAF 447
            :|..|...:|..:..||::|.||..||.|:||:|.::|:|.|.:||.||.:.|..||:.||.:|.
  Rat   437 VGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKHKTREEWQYVFLIAS 501

  Fly   448 GVLVVTAIVYCIWASGDVQPFNDGTNSNKKK 478
            .|.....|.|.::|||:.||:.:....:::|
  Rat   502 LVHYGGVIFYGVFASGEKQPWAEPEEMSEEK 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9254	NP_609664.1	2A0114euk	28..466	CDD:129972	146/462 (32%)
CG9254	NP_609664.1	MFS	82..461	CDD:119392	130/391 (33%)
Slc17a7	XP_038966881.1	MFS_SLC17A6_7_8_VGluT	66..515	CDD:340940	144/458 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342475
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840