DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9254 and slc17a6

DIOPT Version :9

Sequence 1:	NP_609664.1	Gene:	CG9254 / 34773	FlyBaseID:	FBgn0028513	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	XP_004913390.1	Gene:	slc17a6 / 101730310	XenbaseID:	XB-GENE-1011394	Length:	583	Species:	Xenopus tropicalis

Alignment Length:	471	Identity:	152/471 - (32%)
Similarity:	242/471 - (51%)	Gaps:	30/471 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 FVLPQRWILAIMGFFAIFNAYTMRICLSQAITVLVVKRNYTIFHTEAICEPDDQSDPSSTFEGGD 82
            |.||:|:|:|||.......::.:|..|..||..:|  .|.||.|...|.:           |...
Frog    65 FGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMV--NNSTIHHGGKIIK-----------EKAK 116

  Fly    83 YDWSQEKQGLILASFYIGYIVTHLPGGILADKFGGKWTLSLGIFFTAIFTLLTPVC--IVYGGAD 145
            ::|..|..|:|..||:.|||||.:|||.:|.:..........|..|:...:|.|..  :.||
Frog   117 FNWDPEIVGMIHGSFFWGYIVTQIPGGYIASRLAANRVFGAAIVLTSTLNMLIPSAARVHYG--- 178

  Fly   146 ALIVLRVLMGLGEGTTFPALSVLLASWVPANERGMLGALVLGGGQMGSIAGNIISGYVLSSMDWP 210
            .:|.:|:|.||.||.|:||...:.:.|.|..||..|......|...|::....::|.::....|.
Frog   179 CVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWS 243

  Fly   211 WVFYVFAIIALVWFVVFTLVCFSSPFTHPYIKPEERAFLAQEV-------PPPDKNKPKTPFFAI 268
            .||||:....|||::.:.||.:.||..||.|..|||.::.:.:       .|.:|.  |||:...
Frog   244 SVFYVYGCFGLVWYLFWILVSYESPAKHPTITDEERNYIEESIGESANILGPVEKF--KTPWRKF 306

  Fly   269 LTSIPMWALISAQIGHDWGFYIMVSYLPKYMSDVLRFSIKSNGLYSSLPYVTMWIMSLLSGCVAD 333
            .||:|::|:|.|.....|.||:::...|.|..:|..|.|...|:.|::|::.|.|:..:.|.:||
Frog   307 FTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIAD 371

  Fly   334 QMIKRNCMSTTNTRKIMTGVAAFG-PAVFMVAASYAGCNRGMVVALFTITMGLMGTYYAGMKLTP 397
            .:..:..:|||..|||| ....|| .|..::...|:. ::|:.::...:.:|..|...:|..:..
Frog   372 FLRSKQILSTTTVRKIM-NCGGFGMEATLLLVVGYSH-SKGVAISFLVLAVGFSGFAISGFNVNH 434

  Fly   398 LDMSPNYAGTLMAITNGIGAITGVVSPYLVGVMTPNATLLEWRLVFWVAFGVLVVTAIVYCIWAS 462
            ||::|.||..||.|:||:|.::|:|.|.:||.||.:.:..||:.||.:|..|.....|.|.|:||
Frog   435 LDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHKSREEWQYVFLIAALVHYGGVIFYGIFAS 499

  Fly   463 GDVQPFNDGTNSNKKK 478
            |:.||:.|...::.:|
Frog   500 GEKQPWADPEQTSDEK 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9254	NP_609664.1	2A0114euk	28..466	CDD:129972	142/447 (32%)
CG9254	NP_609664.1	MFS	82..461	CDD:119392	126/388 (32%)
slc17a6	XP_004913390.1	MFS_SLC17A6_7_8_VGluT	74..498	CDD:340940	140/443 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000