DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9254 and slc37a3

DIOPT Version :9

Sequence 1:	NP_609664.1	Gene:	CG9254 / 34773	FlyBaseID:	FBgn0028513	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	XP_005174644.1	Gene:	slc37a3 / 100331554	ZFINID:	ZDB-GENE-170302-2	Length:	494	Species:	Danio rerio

Alignment Length:	515	Identity:	102/515 - (19%)
Similarity:	182/515 - (35%)	Gaps:	134/515 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 IMGFFAIFNAYTM-----------RICLSQAITVLVVKRNYTIFHTEAICEPDDQSDPSSTFEGG 81
            ::.|...|.:|.:           ::.:|...|...:::|.|.|          ...|:.|:||.
Zfish    10 LLTFLLTFFSYVLLHASRKTFSNVKVSISAQWTPSALQQNGTAF----------TLSPTETWEGN 64

  Fly    82 DYDWSQEKQGLILAS----FYIGYIVTHLPGGILADKFGGKWTLSLGIFFTAI----FTLLTPVC 138
            .......:..|.|.:    |...|.|.....|::.|:|..::.||.|:..:||    |..||...
Zfish    65 ALFADMGEATLFLGALDSIFLFSYAVGLYVSGVIGDRFNLRYVLSFGLCGSAITEFVFGTLTEWL 129

  Fly   139 IVYGGADALIVLRVLMGLGEGTTFPALSVLLASWVPANERGMLGALVLGGGQMGSIAGNIISGYV 203
            ..| ......||.|:.||.:.|.:|.:..::.:|...:.||    .|.|.....:..|||:..::
Zfish   130 HFY-NVYLYCVLWVINGLLQSTVWPCVVAIMGNWFGKSGRG----FVFGLWSACASVGNILGAFL 189

  Fly   204 LSSMDWPWVFYVFAIIALVWFVVFTLVCFS------------------SPFT------HPYIKPE 244
            .||:......|.|.:.::|.|....:|.|.                  .|.|      .|.:..|
Zfish   190 ASSVLKYGYEYAFLVTSVVQFAGGVVVFFGLLTSPKEIGLNDYFETGLRPVTRDSDSQRPLMSDE 254

  Fly   245 ERAFLAQ--------EVPPPDKNKPKTPFFA--ILTSIPMWALISAQIG-HDWGFYIMVSYLPKY 298
            |.....:        |.|.|........||.  .|..:..::|..|.:. .::.|:.   :||.|
Zfish   255 EDELTDEYSSIQQQDEEPQPQPQPRAIGFFQAFCLPGVLPYSLAYACLKLVNYSFFF---WLPFY 316

  Fly   299 MS--------DVLRFSI----------KSNGLYSSL-----PYVTMWIMSLLSGCVA------DQ 334
            :|        :..|.|:          ...||.|.|     |.:.:.::..:...|.      :|
Zfish   317 LSKNFGWKEVEADRLSVWYDVGGIIGGTVQGLISDLLGKRAPVLAISLLLAMGSLVGYSHSPNNQ 381

  Fly   335 MIKRNCMSTTNTRKIMTGVAAFGPAVFMVAASYAGCNRGMVVALFTITMGLMGTYYAGMKLTPLD 399
            ::....::|       ||....||:             .|:.:..:..:|         :...|.
Zfish   382 LVNGALLAT-------TGFLIGGPS-------------NMISSAISADLG---------RQEALH 417

  Fly   400 MSPNYAGTLMAITNGIGAITGVVSPYLVGVMTPNATLLEWRLVFWVAFGVLVVTAIVYCI 459
            .|.....|:..|.:|.|:|......|||.::   .:.|.|..||:. |.::...::::.|
Zfish   418 NSQQALATVTGIVDGTGSIGAAGGQYLVSLI---ESKLGWMCVFYF-FIIMTGCSVLFII 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9254	NP_609664.1	2A0114euk	28..466	CDD:129972	102/515 (20%)
CG9254	NP_609664.1	MFS	82..461	CDD:119392	90/450 (20%)
slc37a3	XP_005174644.1	UhpC	1..479	CDD:225180	102/515 (20%)
slc37a3	XP_005174644.1	MFS	65..472	CDD:119392	89/447 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582611
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840