Protein Alignment kuz and ADAM9

DIOPT Version :9

• Sequence 1: NP_477187.1
• Gene: kuz / 34772
• FlyBaseID: FBgn0259984
• Length: 1238
• Species: Drosophila melanogaster
• Sequence 2: XP_016869431.1
• Gene: ADAM9 / 8754
• HGNCID: 216
• Length: 821
• Species: Homo sapiens
• Alignment Length: 1009
• Identity: 211/1009 - (20%)
• Similarity: 313/1009 - (31%)
• Gaps: 365/1009 - (36%)

  Fly   105 PIDVSTDHIYEGEVIGDRNSYVFGSIHNGVFEGKIITERDAYYVEHAKHYFPTNRTATTTPPSTS 169
            |..|:|.|:......|...|..||.:                     ||      |..::...||
Human     3 PTPVTTPHLPTLAHWGLNFSVRFGEV---------------------KH------TNCSSFQQTS 40

  Fly   170 TTSSATTAT------KSTQPTRPLAKSNTSTTAVNSKTENFIKKIAESTTTSQQLPE----YTES 224
            ..||....|      :..:..||.:|..:.......|     :.|.........|||    ||.:
Human    41 HLSSYEIITPWRLTRERREAPRPYSKQVSYVIQAEGK-----EHIIHLERNKDLLPEDFVVYTYN 100

  Fly   225 SSSSTTTFPPTTEYFEDEKERNAEDELDFHSIIYKESHVEDAYENVREGHVA--------GCGIT 281
            ...:..|..|.                     |....|.....|.|....:|        |....
Human   101 KEGTLITDHPN---------------------IQNHCHYRGYVEGVHNSSIALSDCFGLRGLLHL 144

  Fly   282 DEVSQWMENIQNSA-VEELPEPMSKDYQK-----LHRKQLHKKSAPQQQQQPHPPKKYISGDEDF 340
            :..|..:|.:|||: .|.:...|...|::     :..|.:.|::|..::::|
Human   145 ENASYGIEPLQNSSHFEHIIYRMDDVYKEPLKCGVSNKDIEKETAKDEEEEP------------- 196

  Fly   341 KYPHQKYTKEANFAEGAFYDPSTGRRLGSSANVADWHQLVHERVRRATDNGAGDRGSSGGSGRGR 405
                                ||..:.|               |.|||.
Human   197 --------------------PSMTQLL---------------RRRRAV----------------- 209

  Fly   406 EDNKNTCSLYIQTDPLIWRHIREGIADHDR----GRKYEVDEKTREEITSLIAHHVTAVNYIYRN 466
            ........|:|             :.|.:|    ||.   ....|||:. |:|:::.:: ||.
Human   210 LPQTRYVELFI-------------VVDKERYDMMGRN---QTAVREEMI-LLANYLDSM-YIM-- 254

  Fly   467 TKFDGRTEHRNIRFEVQRIKIDDDSACRNSYNGPHNAFCNEHMDVSNFLNLHSLEDHSDFCLAYV 531
                     .|||..:..::|..:....|...|..:...|.......||......|.:...|...
Human   255 ---------LNIRIVLVGLEIWTNGNLINIVGGAGDVLGNFVQWREKFLITRRRHDSAQLVLKKG 310

  Fly   532 FTYRDFTGGTLGLAWVASASGAS--GGICEKYKTYTETVGGQYQSTKRSLNTGIITFVNYNSRVP 594
            |      |||.|:|:|.:....|  |||         .|.||            ||...:.|.|
Human   311 F------GGTAGMAFVGTVCSRSHAGGI---------NVFGQ------------ITVETFASIV- 347

  Fly   595 PKVSQLTLAHEIGHNFGSPHDYPQECRPGGLNGNYIMFASATSGDRPNNSKFSPCSIRNISNVL- 658
                    |||:|||.|..||..::|..|..:   .:..|..||.|    .||.||..:...:.
Human   348 --------AHELGHNLGMNHDDGRDCSCGAKS---CIMNSGASGSR----NFSSCSAEDFEKLTL 397

  Fly   659 ----DVLVGNTKRDCFKASEGAFCGNKIVESGEECDCGFNEEECK-DKCCYPRLISEYDQSLNSS 718
                :.|:...|.|  :|.....||||:|::||||||| ..:||: |.||
Human   398 NKGGNCLLNIPKPD--EAYSAPSCGNKLVDAGEECDCG-TPKECELDPCC--------------- 444

  Fly   719 AKGCTRRAKTQCSPSQGPCCLSNSCTFVPTSYHQKCKEET-ECSWSSTCNGTTAECPEPRHRDDK 782
             :|.|.:.|:....:.|.||  ..|.|:|..  ..|:.:| ||.....|||::..|.......:.
Human   445 -EGSTCKLKSFAECAYGDCC--KDCRFLPGG--TLCRGKTSECDVPEYCNGSSQFCQPDVFIQNG 504

  Fly   783 TMCNNGTALCIRGECS--GSPCLLWNMTK-------CFLTSTTLPHVSKRKLCDLACQDGNDTST 838
            ..|.|..|.|..|.|.  .:.|.:...:|       ||:...     ||..........||:...
Human   505 YPCQNNKAYCYNGMCQYYDAQCQVIFGSKAKAAPKDCFIEVN-----SKGDRFGNCGFSGNEYKK 564

  Fly   839 CRSTSEFADKY---NIQK--------------------GGISLQPGSP----------------- 863
            |.:.:....|.   |:|:                    .|:..|.||.
Human   565 CATGNALCGKLQCENVQEIPVFGIVPAIIQTPSRGTKCWGVDFQLGSDVPDPGMVNEGTKCGAGK 629

  Fly   864 -CDNFQ-------GY-CDVFLKCR-----------------------------AVDADGPLLRLK 890
             |.|||       .| |||..||.                             :||: ||.....
Human   630 ICRNFQCVDASVLNYDCDVQKKCHGHGVCNSNKNCHCENGWAPPNCETKGYGGSVDS-GPTYNEM 693

  Fly   891 NLLLNRKTLQTVAEWIVDNWYLVVLMGVAFIVVMGSFIKCCAVHTPSSNPKKRRARRISETLRAP 955
            |..|.        :.::..::|:|.:.|..|.:   |||...:.  .|..:|:|    |:|..:.
Human   694 NTALR--------DGLLVFFFLIVPLIVCAIFI---FIKRDQLW--RSYFRKKR----SQTYESD 741

  Fly   956 MNTLRRMQRHPNQRGAGPRSIPP--PAHEAQHYS 987
            ........|.|   |:.||.:.|  |..|...|:
Human   742 GKNQANPSRQP---GSVPRHVSPVTPPREVPIYA 772

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kuz	NP_477187.1	ZnMc_TACE_like	410..677	CDD:239798	65/277 (23%)
		Reprolysin_2	450..659	CDD:290307	52/215 (24%)
		Disintegrin	684..776	CDD:278623	29/93 (31%)
ADAM9	XP_016869431.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D162519at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920