| Sequence 1: | NP_477187.1 | Gene: | kuz / 34772 | FlyBaseID: | FBgn0259984 | Length: | 1238 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_997080.1 | Gene: | ADAM15 / 8751 | HGNCID: | 193 | Length: | 863 | Species: | Homo sapiens |
| Alignment Length: | 754 | Identity: | 172/754 - (22%) |
|---|---|---|---|
| Similarity: | 244/754 - (32%) | Gaps: | 254/754 - (33%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 410 NTCSL----YIQTD-----PLIWRHIREGIADHDRGRKYEVDEKTREEITSLIAHHVTAVNY--- 462
Fly 463 ---IYRNTK----FDGRTEHRNIRFEV-------QR--IKIDDDSACRNSYNGPHNAFCNEHMDV 511
Fly 512 SNFLN---LHSLE--DHSDFCLAYVFTYRDFTGGTLGLAWVASASGASGGICEKYKTYTETVGGQ 571
Fly 572 YQSTKRSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPHDYP-QECR-PGGLNGNYIMFAS 634
Fly 635 ATSGDRPNNSKFSPCSIRNISNVLDVLVGNT--KRDCFKASEGAFCGNKIVESGEECDCGFNEEE 697
Fly 698 CKDKCCYPRLISEYDQSLNSSAKGCTRRAKTQCSPSQGPCCLSNSCTFVPTSYHQKCK-EETECS 761
Fly 762 WSSTCNGTTAECPEPRHRDDKTMCNNGTALCIRGECS--GSPC-LLWN------MTKCFLTSTTL 817
Fly 818 -------------PHVS---KRKLC-DLACQDGN-------------DTSTCRSTSEFADKYNIQ 852
Fly 853 KG-----------GISLQPGSPCDNFQ-------------------GYCDVFLKCRAVDADGP-- 885
Fly 886 -LLRLK-------NLLLNRKTLQTVAEWIVDNWY-------LVVLMGVAFIVVMGSFIKCCAVHT 935
Fly 936 PSSNPKKR-----RARRISETLRA--------------PMNTLRRMQR----HPN---------- 967
Fly 968 ----QRGAGPRSIPPPAH----EAQHYSRGGDGRGGGGG 998 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| kuz | NP_477187.1 | ZnMc_TACE_like | 410..677 | CDD:239798 | 68/303 (22%) |
| Reprolysin_2 | 450..659 | CDD:290307 | 50/234 (21%) | ||
| Disintegrin | 684..776 | CDD:278623 | 31/92 (34%) | ||
| ADAM15 | NP_997080.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 22..45 | ||
| Pep_M12B_propep | 62..154 | CDD:279848 | |||
| Cysteine switch. /evidence=ECO:0000250 | 177..184 | 3/6 (50%) | |||
| Reprolysin | 213..413 | CDD:279729 | 55/250 (22%) | ||
| ZnMc_adamalysin_II_like | 213..411 | CDD:239797 | 55/248 (22%) | ||
| DISIN | 430..504 | CDD:214490 | 31/93 (33%) | ||
| Cell attachment site. /evidence=ECO:0000255|PROSITE-ProRule:PRU00068 | 484..486 | 0/1 (0%) | |||
| ACR | 508..649 | CDD:214743 | 27/140 (19%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 736..863 | 23/106 (22%) | |||
| SH3-binding. /evidence=ECO:0000255 | 815..821 | 3/5 (60%) | |||
| SH3-binding. /evidence=ECO:0000255 | 850..856 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D162519at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.920 | |||||