| Sequence 1: | NP_477187.1 | Gene: | kuz / 34772 | FlyBaseID: | FBgn0259984 | Length: | 1238 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_003465.3 | Gene: | ADAM12 / 8038 | HGNCID: | 190 | Length: | 909 | Species: | Homo sapiens |
| Alignment Length: | 830 | Identity: | 179/830 - (21%) |
|---|---|---|---|
| Similarity: | 263/830 - (31%) | Gaps: | 293/830 - (35%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 351 ANFAEGAFYDPSTGRRLGSSANVADWHQLVHERVRRATDNG------AGDRG------------- 396
Fly 397 -----------------SSGGSGRGREDNKNTCSLYIQTDP-LIW--RHIREG-----------I 430
Fly 431 ADHDRGRKYEVD-EKTREEITSLIAHHVTAVNYIYRNTKFDGRTEHRNIRFEVQRIKIDDD---- 490
Fly 491 SACRNSYNGPHNAFCNEHMDVSNFLNLHSLEDHSDFCLAYVFTYRDFTGGTLGLAWVASASGA-- 553
Fly 554 SGGICEKYKTYTETVGGQYQSTKRSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPHDYPQ 618
Fly 619 ---ECRPGGLNGNYIMFASATSGDRPNNSKFSPCSIRNISNVLDVLVG------NTKRDCFKASE 674
Fly 675 GAFCGNKIVESGEECDCGFNEEECKDKCCYPRLISEYDQSLNSSAKGCTRRAKTQCSPSQGPCCL 739
Fly 740 SNSCTFVPTSYHQKCKEET-ECSWSSTCNGTTAECPEPRHRDDKTMCNNGTALCIRGECS--GSP 801
Fly 802 CL-LWNMTK------CF--LTSTTLPH-----VSKRKL--CD--------LACQDGNDTSTCRST 842
Fly 843 SEFADKYNI--QKGGISL-------------QPG----------------SPCDNFQ--GYCDVF 874
Fly 875 LKCRAVDADGPLLRLKNLLLNRKTLQTVAEWI--------------------VDNWYLVV----- 914
Fly 915 ---LMGVAFIVVMG----------------SFIKC------------CAVH-----------TPS 937
Fly 938 SNPKKRRARRISE----TLRAPMNTLRRMQRHPNQRGAGPRSIPPPAHEA 983 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| kuz | NP_477187.1 | ZnMc_TACE_like | 410..677 | CDD:239798 | 69/296 (23%) |
| Reprolysin_2 | 450..659 | CDD:290307 | 52/217 (24%) | ||
| Disintegrin | 684..776 | CDD:278623 | 28/92 (30%) | ||
| ADAM12 | NP_003465.3 | Pep_M12B_propep | 60..161 | CDD:279848 | 13/68 (19%) |
| Cysteine switch. /evidence=ECO:0000250 | 177..184 | 2/6 (33%) | |||
| Reprolysin | 214..416 | CDD:279729 | 59/256 (23%) | ||
| ZnMc_adamalysin_II_like | 214..414 | CDD:239797 | 59/254 (23%) | ||
| DISIN | 439..507 | CDD:214490 | 23/88 (26%) | ||
| ACR | 510..652 | CDD:214743 | 29/142 (20%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 822..862 | 2/4 (50%) | |||
| SH3-binding, class II. /evidence=ECO:0000250 | 828..834 | ||||
| SH3-binding, class I. /evidence=ECO:0000250 | 834..841 | ||||
| SH3-binding, class I. /evidence=ECO:0000250 | 885..891 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D162519at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.920 | |||||