Protein Alignment kuz and Adam30

DIOPT Version :9

• Sequence 1: NP_477187.1
• Gene: kuz / 34772
• FlyBaseID: FBgn0259984
• Length: 1238
• Species: Drosophila melanogaster
• Sequence 2: NP_081941.1
• Gene: Adam30 / 71078
• MGIID: 1918328
• Length: 732
• Species: Mus musculus
• Alignment Length: 548
• Identity: 122/548 - (22%)
• Similarity: 194/548 - (35%)
• Gaps: 167/548 - (30%)

  Fly   337 DEDFKYPHQKYT--KEANFAEGAFYDPSTGRRLGSSANVADWHQLVHERVRRA-----------T 388
            |.|:.:...:.|  |..:|.:||   ......|.....:....::||.|.::.           |
Mouse    32 DPDWGFDSYEITIPKVISFKKGA---QGVDSSLSYLLQIEGKARVVHLRPKKLLLPRHLPVFSFT 93

  Fly   389 DNGA--------GDRGSSGGSGRGREDNKNTCSL--------------YIQTDPL----IWRHIR 427
            ..|:        .|:.:..||..|.:::::|.|.              |.|.:||    .:.|:.
Mouse    94 QEGSLIEDYPHIPDQCNYVGSVEGSQESESTLSTCMGGLRGVLNIDSRYYQIEPLRASSSFEHVV 158

  Fly   428 EGIADHDRGRKY--EVDEKT------REEITSLIAHHVTAVNYIYRNTKFDGRTEHRNIRFEVQR 484
            ..:.:.:...:.  .|||:|      .||:..:.:.|.:     |::.::    ....:.|::.|
Mouse   159 YLVTEDNFNNETCGVVDEETGGQTAEEEEMARISSFHQS-----YKHQRY----LELVMVFDLDR 214

  Fly   485 I--------KIDDDSACRNSYNGPHNAFCNEHMDVSNFLNLHSLEDHSDFCLAYVFTY------- 534
            .        ::.||:....|....:      ..|||..:.|.:||         |:||
Mouse   215 FVFARGNMSRMVDDAILLASIADTY------FQDVSLKIQLKALE---------VWTYYNRIRLY 264

  Fly   535 ---------------RDFTGGTLGLAW---------VASASGASGGICEKYKTYTETVGGQYQST 575
                           |:.....|...|         :.:.:.:.|..||::...:.:
Mouse   265 YPSLSEVLGQFVHYKRNSMHHRLPADWFHLYIARRYIDANAWSWGRACEEFHAGSAS-------- 321

  Fly   576 KRSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPHDYPQECRPGGLNGNYIMFASATSGDR 640
                     :|:|.|...|...:    |||:||..|..|| .:.|:..| ..:.||....|.
Mouse   322 ---------SFLNVNILGPATWT----AHELGHCVGMIHD-EEFCQCRG-RKSCIMGTGRTG--- 368

  Fly   641 PNNSKFSPCSIRNISNVLDVLVGNTKRDCFKASEGAFCGNKIVESGEECDCGFNEEECKDKCCYP 705
                 ||.||...........:.....|..|......|||||||:.||||||..|:..||.||.|
Mouse   369 -----FSNCSYHQYFLHASYKMSYCLSDFPKLHIVERCGNKIVENKEECDCGSKEDCKKDLCCGP 428

  Fly   706 RLISEYDQSLNSSAKGCTRRAKTQCSPSQGPCCLSNSCTFVPTSYHQKC-KEETECSWSSTCNGT 769
                           .|..:....|  |.|.||  :.|.|:|:.|  .| ||..||.....|:||
Mouse   429 ---------------DCKWKEGVNC--SSGLCC--HKCNFLPSGY--VCRKEVNECDLEEYCDGT 472

  Fly   770 TAECPEPRHRDDKTMCNNGTALCIRGEC 797
            :..||:..::.|.|.|.|| ..|.|..|
Mouse   473 SGVCPDDSYKQDGTPCRNG-GFCFRKGC 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kuz	NP_477187.1	ZnMc_TACE_like	410..677	CDD:239798	58/331 (18%)
		Reprolysin_2	450..659	CDD:290307	43/247 (17%)
		Disintegrin	684..776	CDD:278623	33/92 (36%)
Adam30	NP_081941.1	Pep_M12B_propep	58..158	CDD:279848	17/99 (17%)
		Reprolysin	202..393	CDD:279729	42/240 (18%)
		ZnMc_adamalysin_II_like	202..391	CDD:239797	41/238 (17%)
		Disintegrin	407..479	CDD:278623	33/92 (36%)
		ACR	483..624	CDD:214743	8/18 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836127
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D162519at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.850