Protein Alignment kuz and adam33

DIOPT Version :9

• Sequence 1: NP_477187.1
• Gene: kuz / 34772
• FlyBaseID: FBgn0259984
• Length: 1238
• Species: Drosophila melanogaster
• Sequence 2: XP_012819411.2
• Gene: adam33 / 677728
• XenbaseID: XB-GENE-988107
• Length: 913
• Species: Xenopus tropicalis
• Alignment Length: 931
• Identity: 194/931 - (20%)
• Similarity: 284/931 - (30%)
• Gaps: 389/931 - (41%)

  Fly   287 WMENIQNSAVEELPEPMSKDYQK-------------LHRKQLHKKSAPQQQQQPHPPKKYISGDE 338
            |::|.:.....||.:.:|....:             |..::.|:..||     .:....|..|
 Frog    40 WLQNERAKRSVELLDKVSGTPDRGEILVTSEGRRLILKVERNHRLFAP-----GYTETHYTDG-- 97

  Fly   339 DFKYPHQKYTKEANFAEGAFYDPSTGRRLGSSANVADWHQLVHERVRRATDNGAGDRGSSGGSG- 402
                  |..|...|..|..:|                     |.:|:...|:.......||.||
 Frog    98 ------QMVTLSPNHTEHCYY---------------------HGQVQGYDDSSVALTTCSGISGL 135

  Fly   403 ---RGRE---------DNKNTCSLYIQTDPLIWRHIREGIADHDRGRKYEVDEKTREEITSLIAH 455
               |..:         ..|.|.|| ::|:.|   .|:.|...|: |.........: |.|:...|
 Frog   136 IVLRTNDSYYLSPLEVSGKETHSL-VRTEHL---PIKGGSCGHE-GHSGSTTSYFK-EFTAPPGH 194

  Fly   456 HVTAVNYIYRNTKFD------------------GRTEHR---------------NIRF------- 480
            |....| ::|:.|:.                  |.|:.|               ||:.
 Frog   195 HRVRRN-VWRSQKYMELFIVADYSMFMKQNRNLGSTKQRVLEIANYVDKFYMSMNIKVALIGLEV 258

  Fly   481 --EVQRIKIDDDSACRNSYNGPHNAFCNEHMDVSNFL----NLHSLEDHSDFCLAYVFTYRDFTG 539
              |..:..::||:              |:  .:.:||    .|.|.:.|.:   |.:.|...|.|
 Frog   259 WTERDQCDVNDDA--------------ND--SLRSFLQWKQKLRSRKKHDN---AQLITGVTFKG 304

  Fly   540 GTLGLAWVASASGA--SGGICEKYKTYTETVGGQYQSTKRSLNTGIITFVNYNSRVPPKVSQLTL 602
            .|:|:|.:.....|  |||:.   ..::|...|                           :..|:
 Frog   305 TTIGMAPLEGMCTAENSGGVS---MDHSENAIG---------------------------AAATM 339

  Fly   603 AHEIGHNFGSPHDYP---QECRPGGLNGNYIMFASATSGDRPNNSKFSPCS-------------- 650
            |||||||||..||..   .|..|.  .|..||   |.|...|...|||.||
 Frog   340 AHEIGHNFGMSHDNDGCCVEATPE--QGGCIM---AASTGHPFPRKFSRCSQQQLMSYFRKGGGM 399

  Fly   651 -IRNISNVLDVLVGNTKRDCFKASEGAFCGNKIVESGEECDCGFNEEECKDKCCYPRLISEYDQS 714
             :.|:.|..|:::|..            |||..:|.||:|||| ..|||.:.||
 Frog   400 CLFNMPNTNDLVMGKK------------CGNGFLEEGEQCDCG-EPEECTNPCC----------- 440

  Fly   715 LNSSAKGCTRRAKTQCSPSQGPCCLSNSCTFVPTSYHQKCKEET-ECSWSSTCNGTTAECPEPRH 778
               :|..||.:|..:|  :.|.||  ..|..  .|...:|:|.. .|.....|.|....||...:
 Frog   441 ---NANNCTLKAGAKC--AHGECC--QDCRL--KSAGTQCREMAGSCDLPEFCTGDAPFCPSNVY 496

  Fly   779 RDDKTMCNNGTALCIRGEC--SGSPCL-LWNMTKCFLTSTTLPHVSKRKLCDLACQD----GNDT 836
            ..|.:.|..|.|.|..|.|  ....|: ||..     .:...|        |...||    |:..
 Frog   497 MLDGSSCAFGEAYCYNGMCLTHQQQCIHLWGS-----GAVVAP--------DFCFQDVNKAGDQY 548

  Fly   837 STC---------RSTSEFADKYNIQKGGISLQPGSP----CDN---FQGYCDVFLKCRAVDA--- 882
            ..|         :.||..|....||....|.:|..|    .||   ..||   .:||:.|.|
 Frog   549 GNCGKNGRGQFVKCTSRDAKCGKIQCQTSSEKPRDPSMVKVDNTIIINGY---KMKCQGVHAYSM 610

  Fly   883 -----------------DGPLLRLKNLLLNRKTLQTVAEWIVD---------------------- 908
                             ||       ::...:..|..:.:.:|
 Frog   611 QEEEGDPGLVMTGTKCGDG-------MVCKDRRCQNASFFELDQCVSKCNGHGVCNSNRNCHCHS 668

  Fly   909 NW----------------------------------YLVVLMGVAFIVVM-----GSFI------ 928
            .|                                  :||:|:|:|..:|.     ||.:
 Frog   669 GWAPPYCDKPGPGGSQDSGPAPNDIPVGVTIFLVILFLVLLLGLAIAMVYWYRKPGSLLNKWLKK 733

  Fly   929 ---KC--CAVHTPSSN--------------------PKKRRARRI--SETLRA-----PMNTLRR 961
               ||  |....|.:|                    .|:..:|.|  .:|..|     |:|.:|.
 Frog   734 SKAKCSLCKATQPKANRAYSSKIFTMRDISYPVKSDSKQTHSRDIFQGKTTAAQNSSHPVNVVRP 798

  Fly   962 MQRHPN---QRGAGPRSIPPP 979
            ::..|:   |.|...|..|||
 Frog   799 LRPAPSPVIQHGKPLRPPPPP 819

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kuz	NP_477187.1	ZnMc_TACE_like	410..677	CDD:239798	72/332 (22%)
		Reprolysin_2	450..659	CDD:290307	60/274 (22%)
		Disintegrin	684..776	CDD:278623	29/92 (32%)
adam33	XP_012819411.2	Pep_M12B_propep	36..158	CDD:396235	26/151 (17%)
		Reprolysin	206..405	CDD:396140	54/252 (21%)
		DISIN	422..496	CDD:214490	29/94 (31%)
		ACR	498..639	CDD:214743	34/163 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D162519at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010