Protein Alignment kuz and Adamdec1

DIOPT Version :9

• Sequence 1: NP_477187.1
• Gene: kuz / 34772
• FlyBaseID: FBgn0259984
• Length: 1238
• Species: Drosophila melanogaster
• Sequence 2: NP_067450.1
• Gene: Adamdec1 / 58860
• MGIID: 1917650
• Length: 467
• Species: Mus musculus
• Alignment Length: 503
• Identity: 98/503 - (19%)
• Similarity: 164/503 - (32%)
• Gaps: 148/503 - (29%)

  Fly   291 IQNSAVEELPEPMSKDYQKLHRKQL---HKKSAPQQQQQPHPPKKYISGDEDFKYPHQKYTKEAN 352
            ||...::....|..|.::.:..|:|   .|:.....|.:.:       |.|:...|..:|....|
Mouse    26 IQIQVIDATLTPELKPHEIVRPKKLPISQKRGLENNQTERY-------GKEEKYAPEVQYQIILN 83

  Fly   353 FAEGAFYDPSTGRRLGSSANVADWHQLVHERVRRATD-----------NGAGD--RGSSGGSGRG 404
            ..|..|:...|...||.......:.....|..|.:.|           |..|.  |.|:....||
Mouse    84 GEEIVFHLKRTKHLLGPDYTETSYSPRGEESTRHSQDVKPCYYEGHIQNARGSLARISTCDGLRG 148

  Fly   405 ---REDNKNTCSLYIQTD-------PLIWR-------------------HIREGIA------DHD 434
               ..|.:........||       |..|:                   |:|...:      |..
Mouse   149 YFTHRDQRYQIKPLQSTDEGEHAVLPYSWKGQDTVHDKDAEKQVVRKRSHLRTSRSLKNPNEDLL 213

  Fly   435 RGRK------------YEVDEKTREEITSLIAHHVTAVNYIYRNTKFDGRTEHRNIRFEVQRIKI 487
            :|:|            |::......::.:.:...:..:|.||:............|..:..:||:
Mouse   214 QGQKYIGLFLVLDNAYYKLYNGNVTQMRTFLFKVLNLLNMIYKTINIQVSLVGMEIWSDQDKIKV 278

  Fly   488 DDDSACRNSYNGPHNAFCNEHMDVSNFLNL-HSLEDHSDFCLAYVFTYRDFTGGTLGLAWVASAS 551
            :           |:......|....::.|| ..:.:|     |.:.:...|..|.:|:|
Mouse   279 E-----------PNLGATFTHFMRWHYSNLGKRIHNH-----AQLLSGASFRHGRVGMA------ 321

  Fly   552 GASGGICEKYKTYTETVGGQYQSTKRSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPH-D 615
             |....|.     |.:|  .....|:..|..::..               ::||:||..|... .
Mouse   322 -AGNSFCT-----TSSV--SVIEAKKKNNVALVAL---------------MSHELGHALGMKDVP 363

  Fly   616 YPQECRPGGLNGNYIMFASATSGDRPNNSKFSPCSIRNIS-----------NVLDVLVGNTKRDC 669
            |..:|..|....|..:           :||| |.....:|           |...:|:....::.
Mouse   364 YYTKCPSGSCVMNQYL-----------SSKF-PKDFSTVSRSHFQGFLSSRNARCLLLAPDPKNI 416

  Fly   670 FKASEGAFCGNKIVESGEECDCGFNEEECKDKCCYP---RLISEYDQS 714
            .|.:    |||::::.||||||| :.|||.:.||.|   ||.|:.|.|
Mouse   417 IKPT----CGNQVLDVGEECDCG-SPEECTNLCCEPLTCRLKSQPDCS 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kuz	NP_477187.1	ZnMc_TACE_like	410..677	CDD:239798	49/323 (15%)
		Reprolysin_2	450..659	CDD:290307	37/221 (17%)
		Disintegrin	684..776	CDD:278623	18/34 (53%)
Adamdec1	NP_067450.1	Pep_M12B_propep	54..170	CDD:279848	24/122 (20%)
		Reprolysin	217..411	CDD:279729	40/250 (16%)
		ZnMc_adamalysin_II_like	217..408	CDD:239797	39/247 (16%)
		Disintegrin	427..>460	CDD:299186	18/34 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836128
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D162519at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.850