Protein Alignment kuz and Adam4l1

DIOPT Version :9

• Sequence 1: NP_477187.1
• Gene: kuz / 34772
• FlyBaseID: FBgn0259984
• Length: 1238
• Species: Drosophila melanogaster
• Sequence 2: NP_001102747.1
• Gene: Adam4l1 / 500688
• RGDID: 1597022
• Length: 747
• Species: Rattus norvegicus
• Alignment Length: 805
• Identity: 161/805 - (20%)
• Similarity: 245/805 - (30%)
• Gaps: 302/805 - (37%)

  Fly   298 ELPEPMSKDYQKLH----------RKQLHKKSAPQQQQQPHPPKKYISGD-----EDFKY-PHQK 346
            ::|:.|.|.....|          |..:|.|.......|..|  .|.|.|     ||:.: |...
  Rat    52 KVPQRMGKSDMSGHITYSMRFRGQRHVVHMKLKKNMISQNFP--VYTSNDQGAQQEDYPFVPQDC 114

  Fly   347 YTKEANFAEGAFYDPSTGRRLGSSANVADWHQLVHERVRRATDNGAGDRGSSGGSGRGREDNKNT 411
            |          ||....|.. ||.|.:                    |..:.|..|..|.|: :|
  Rat   115 Y----------FYSYLEGVP-GSQATL--------------------DTCTGGLKGMIRVDD-ST 147

  Fly   412 CSLYIQTDPLIWRHIREGIADHDRGRKYEVDEKTR-EEITSLIAHHVTAVNYIYRNTKFDGRTEH 475
            ..:...|....:.|:...:...:|.||   .:|.| :||.:      .|.:.:.:.||..|....
  Rat   148 YEIKPLTSSSKFEHVISLLVVDERSRK---SKKCRNDEIMA------EAGDSLVKETKLAGSPRA 203

  Fly   476 RNI---RFEVQRIKIDDDSACRNSYNGPHNAFCNEHMDVSNFLNL-HSLEDHSD----------- 525
            ..:   |..|:.|.|        .|...|..|.:...:::..|.| .:|...:|
  Rat   204 APVYLWRIHVKSIAI--------MYTVTHQVFLDGGSNITQSLELTMTLNTIADSIYRPSGLIVF 260

  Fly   526 ---FCLAYVFTYRD---FTGGTLGLAWVASASGASGGICEKY----------------------- 561
               .||     :.|   |..|. |..|         .:.|:|
  Rat   261 IRALCL-----WNDGDHFPTGD-GNIW---------RLMERYGYWKARFFWEMHHATAALLISNI 310

  Fly   562 KTYTETVGGQYQSTKRSLNTGII-TFVNYNSRVPPKVSQLTLAHEIGHNFGSPHDYPQECRPGGL 625
            ::..|..|  :|....:.|.|:: |.|..|...   ::...|||.:||.....||     :||
  Rat   311 RSNAEYAG--FQDGVCNPNWGVLYTHVGKNHYF---LAASFLAHAVGHILNVGHD-----KPG-- 363

  Fly   626 NGNYIMF--ASATSGDRPN-NSKFSPCSIRNISNVLDVLVGNTKRDCFKASEGAF---------C 678
               .:.|  :|.|..:.|. :...|.||    .|||...:.:.. .|......::         |
  Rat   364 ---CVCFRRSSCTMHEYPTLHDMMSNCS----HNVLHYRIHDWD-GCLSQPRVSYRWINYAVPRC 420

  Fly   679 GNKIVESGEECDCGFNEEECKDKCCYPRLISEYDQSLNSSAKGCTRRAKTQCSPSQGPCCLSNSC 743
            |||||::||:||||..::...|.||               ...|...|.:.|  :.|.||  .||
  Rat   421 GNKIVDNGEKCDCGSFKDCASDHCC---------------GTTCELTASSVC--ASGGCC--QSC 466

  Fly   744 TFVPTSYHQKCKEETE-CSWSSTCNGTTAECPEPRHRDDKTMCNNGTALCIRGECS--------- 798
            .|.|..  ..|:::.. |.....|:|.:..||...|..|.|.| :..|:|:.|.||
  Rat   467 KFAPIG--TVCRQKGGICDLPEYCSGKSEHCPGNFHIMDGTPC-SPLAVCVSGNCSDRQLQCQAL 528

  Fly   799 -------GSPC---------------------------------LLWNMTKC----FLTS----T 815
                   .||.                                 :|.....|    |:..    |
  Rat   529 FGFNVKDASPACYKELNTKGDRFGNCGIREVRGGSKPMRCQEEDVLCGQIHCDGVKFIPGGGEHT 593

  Fly   816 TLPHVSKRKLCDLACQDGNDTSTCRSTSEFADKYNIQKGGISLQPGSPCD--------------- 865
            |..|:....:.:..| .|.|........|.    .:...|.:..||..|.
  Rat   594 TFHHIKVMDIKEEQC-FGYDAHHGAQVPEM----GLVVDGATCGPGKYCRGQRCVFHQTMGFNCN 653

  Fly   866 ----NFQGYCDVFLKCRAVDA----------------DGPL------LRLK-NLLLNRKTLQTVA 903
                |::|.|:....|..|..                .||.      :|.| ::.:||
  Rat   654 VSKCNYKGVCNNQGNCHCVQGWQPPDCIEKGAGGSVNSGPAVIYEKRIRAKVHMSINR------- 711

  Fly   904 EWIVDNWYLVVLMGVAFIVVMGSFI 928
                    |::|:|....::..|.|
  Rat   712 --------LIILLGTRMFLIFASII 728

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kuz	NP_477187.1	ZnMc_TACE_like	410..677	CDD:239798	62/315 (20%)
		Reprolysin_2	450..659	CDD:290307	50/256 (20%)
		Disintegrin	684..776	CDD:278623	25/92 (27%)
Adam4l1	NP_001102747.1	Pep_M12B_propep	60..163	CDD:279848	27/136 (20%)
		ZnMc_adamalysin_II_like	214..404	CDD:239797	46/232 (20%)
		Reprolysin	214..403	CDD:279729	45/231 (19%)
		Disintegrin	426..499	CDD:278623	25/93 (27%)
		ACR	502..643	CDD:214743	24/146 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D162519at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010