Protein Alignment kuz and Adam26b

DIOPT Version :9

• Sequence 1: NP_477187.1
• Gene: kuz / 34772
• FlyBaseID: FBgn0259984
• Length: 1238
• Species: Drosophila melanogaster
• Sequence 2: NP_001009547.1
• Gene: Adam26b / 382007
• MGIID: 3588304
• Length: 699
• Species: Mus musculus
• Alignment Length: 562
• Identity: 134/562 - (23%)
• Similarity: 204/562 - (36%)
• Gaps: 163/562 - (29%)

  Fly   324 QQQPHPPKK-YISG--DEDFKYPHQKYTKEANFA--EGAFYDPSTGRRLGSSANVADWHQLVHER 383
            :|:|..|.. |..|  |||   |.........|.  :|......|...:...::.:.:..|.::
Mouse    88 EQRPFVPNDCYYHGYVDED---PESLVILNTCFGSLQGTLEINGTTYEIMPKSSTSTFEHLAYK- 148

  Fly   384 VRRATDNGAGDRGSSGGSGRGREDNKNTCSLYIQTDPLIWRHIREGIADHDRGRKYEVDEKTREE 448
                .|||..: .|....|...|:......|..:..|.:.:...|....|.|..:|.|
Mouse   149 ----MDNGDSE-PSPMRCGLSEEEIAQQRKLRERNAPTLLQIPHENWWTHHRFIEYFV------- 201

  Fly   449 ITSLIAHHVTAVNYIYRNTKFDGRTEHRNIRFEVQ-RIKIDDDSACRNSYNGPHNAFCNEHMDV- 511
               :|.|.    .|::||         .||...:| .::|         .||.:..:.....||
Mouse   202 ---VIDHK----QYVHRN---------NNITTCIQDMLQI---------VNGVNGYYLQIDTDVV 241

  Fly   512 ---------SNFLN--LHSLEDHSDFC--------------LAYVFTYRDFTGGTLGLAWVASAS 551
                     .|::|  |...:...|||              :.::...:.: |..||||::|.
Mouse   242 LTALEIWNEKNYINVELSIFKVLGDFCTWKQNMFGNRIRHDIIHLLVRQGY-GLYLGLAYLAD-- 303

  Fly   552 GASGGICEKYKTYTETVGGQYQSTKRSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPHDY 616
                 :|..|                  |.|:.:|:   |.|...::.: :|||:|||.|..||
Mouse   304 -----VCTPY------------------NCGVSSFL---SDVMSDMAHI-VAHEMGHNLGMKHD- 340

  Fly   617 PQECRPGGLNGNYIMFASATSGDRPNNSKFSPCSIRNISNVLDVLVGNTKRDCFKASEGAF---- 677
                   |:.....:.....:..:.|:.|||.||...:.:|:      |||.|......|.
Mouse   341 -------GIGCTCGLKDCLMAPYKTNSPKFSNCSYEEMYSVV------TKRSCLYDIPEALVTNL 392

  Fly   678 --CGNKIVESGEECDCGFNEEECKDKCCYPRLISEYDQSLNSSAKGCTRRAKTQCSPSQGPCCLS 740
              ||||:||.|||||||..|...:|.||               :..|..:...||  :.|.||
Mouse   393 TVCGNKVVEEGEECDCGSTESCLQDPCC---------------SSDCVLKPGAQC--AFGLCC-- 438

  Fly   741 NSCTFVPTSYHQKCKEE-TECSWSSTCNGTTAECPEPRHRDDKTMCNNGTALCIRGEC--SGSPC 802
            ..|.|:.|.  ..|:|| .||.....||||:||||...::.|...| :|...|.:.||  ....|
Mouse   439 QDCQFLKTG--TVCREEKNECDLPEWCNGTSAECPGDVYKADGIPC-SGEGYCYKMECHQRDEQC 500

  Fly   803 --LLWNMTK-----CFLTSTTL--------PHVSKRKLCDLA 829
              :..|.::     |::.....        ...||.|:|:||
Mouse   501 RKIFGNGSRSADEICYMEMNRRGDRFGNCGNDSSKYKICELA 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kuz	NP_477187.1	ZnMc_TACE_like	410..677	CDD:239798	60/293 (20%)
		Reprolysin_2	450..659	CDD:290307	49/235 (21%)
		Disintegrin	684..776	CDD:278623	34/92 (37%)
Adam26b	NP_001009547.1	Pep_M12B_propep	39..144	CDD:279848	12/58 (21%)
		Reprolysin	195..385	CDD:279729	56/265 (21%)
		ZnMc_adamalysin_II_like	195..383	CDD:239797	56/263 (21%)
		Disintegrin	401..474	CDD:278623	34/93 (37%)
		ACR	477..613	CDD:214743	15/67 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836133
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D162519at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.850