DRSC/TRiP Functional Genomics Resources

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Protein Alignment kuz and Adam32

DIOPT Version :9

Sequence 1:NP_477187.1 Gene:kuz / 34772 FlyBaseID:FBgn0259984 Length:1238 Species:Drosophila melanogaster
Sequence 2:NP_700446.2 Gene:Adam32 / 353188 MGIID:2653822 Length:754 Species:Mus musculus


Alignment Length:431 Identity:87/431 - (20%)
Similarity:144/431 - (33%) Gaps:148/431 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   439 YEVDEKTREEITSLIAHHV-TAVNY-IYRNTKFDGRTEHRNIRFEVQRIKIDDDSACRNSYNGPH 501
            |::..|.:|.|.:..:.:: ...|| |..|.|  .::..:|:......:.|..|.|..:......
Mouse   145 YKLGNKEKELIFNKNSRNIEMPTNYGILINKK--PKSPFKNLFPLYLEMSIVVDKALYDYLGSDS 207

  Fly   502 NAFCNEHMDVSNFLN-----------LHSLEDHSD-----------------------------F 526
            |...|:.:::.:.:|           |.|||..||                             .
Mouse   208 NIVTNKIIEIISLINSVFAQLKVTIVLSSLELWSDKNKIPTVGEADELLHKFLEWKQAYLTLRPH 272

  Fly   527 CLAYVFTYRDFTGGTLGLAWVASASGASGGICEKYKTYTETVGGQYQSTKRSLNTGIITFVNYNS 591
            .:||:|.|.:                           |...:|..|        .|.:...:|::
Mouse   273 DVAYLFIYNE---------------------------YPNYMGATY--------PGKMCTAHYSA 302

  Fly   592 RVPPKVSQLT-------LAHEIGHNFGSPHDYPQECRPGG----LNGNYIMFASATSGDRPNNSK 645
            .:......:|       |...:|.:.|..:|.|::|....    :|...:.:....|        
Mouse   303 GITMYPKDMTLEAFSVILTQMLGLSLGISYDEPEKCYCSESICIMNPRAMQYGGVKS-------- 359

  Fly   646 FSPCSIRNISNVLDVLVGNTKRDCFKASEG---------------AFCGNKIVESGEECDCGFNE 695
            ||.||:.:..:             ||::||               |.|||..||..|.|||| :|
Mouse   360 FSNCSLNDFEH-------------FKSNEGAKCLQNKPQMQRTAAAVCGNGKVEGDEICDCG-SE 410

  Fly   696 EEC-KDKCCYPRLISEYDQSLNSSAKGCTRRAKTQC---SPSQGPCCLSNSCTFVPTSYHQKCKE 756
            .|| .|.||.|              ..|..:|...|   ||| ..||  .:|.|:|..:..:.::
Mouse   411 AECGPDSCCEP--------------NRCVLKAGRACDSKSPS-STCC--KNCQFLPEKHQCRPEK 458

  Fly   757 ETECSWSSTCNGTTAECPEPRHRDDKTMCNNGTALCIRGEC 797
            ...|.....|||::..||.....::..:|.....:|..|:|
Mouse   459 HLYCDIPEVCNGSSGNCPPDVTINNGHVCKESGTICYNGDC 499

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kuzNP_477187.1 ZnMc_TACE_like 410..677 CDD:239798 48/305 (16%)
Reprolysin_2 450..659 CDD:290307 40/261 (15%)
Disintegrin 684..776 CDD:278623 30/95 (32%)
Adam32NP_700446.2 Pep_M12B_propep 40..144 CDD:279848
Reprolysin 188..384 CDD:279729 38/251 (15%)
ZnMc_adamalysin_II_like 188..382 CDD:239797 38/249 (15%)
Disintegrin 400..479 CDD:278623 30/96 (31%)
ACR 483..622 CDD:214743 4/17 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 720..754
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D162519at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.920

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