Protein Alignment kuz and Adamts17

DIOPT Version :9

• Sequence 1: NP_477187.1
• Gene: kuz / 34772
• FlyBaseID: FBgn0259984
• Length: 1238
• Species: Drosophila melanogaster
• Sequence 2: XP_218753.6
• Gene: Adamts17 / 293004
• RGDID: 1308783
• Length: 1122
• Species: Rattus norvegicus
• Alignment Length: 587
• Identity: 116/587 - (19%)
• Similarity: 190/587 - (32%)
• Gaps: 194/587 - (33%)

  Fly   397 SSGGSGRGREDNKNTCSLYIQTDPLIWRHIREGIADHD-RGRKYEV---DEKTREEI----TSLI 453
            |:.|.....|..:..|.:..:..|      |:|....| |.|:..:   :|.|.|.:    ..::
  Rat   185 STSGLATKVEGPRQHCKVVTEEKP------RKGKLSWDWRERRNAIRLTNEHTVETLVVADADMV 243

  Fly   454 AHH---------VTAVNYIYRNTKFDGRTEHRNIRFEVQRIKIDDDSACRNSYNGPH-----NAF 504
            .:|         :|.:|.:|  ..|..::....|..:|.::.:......:.|. |.|     .:|
  Rat   244 QYHGAEAAQRFILTVMNMVY--NMFQHQSLGIKINIQVTKLVLLRQRPAKLSI-GHHGERSLESF 305

  Fly   505 C---NEHMDVSNFLNLHSL----ED-----------HSDFCLAYVFTYRDFTGGTLGLAWVASAS 551
            |   ||....:.:|..:.:    :|           .:|||:     ::|....|:|:|::
  Rat   306 CHWQNEEYGGARYLGNNQVPGGKDDTPPVDAAVFVTRTDFCV-----HKDEPCDTVGIAYL---- 361

  Fly   552 GASGGICEKYKTYTETVGGQYQSTKRSL----NTGI-ITFVNYNSRVPPKVSQLTLAHEIGHNFG 611
               ||:|               |.||..    :.|: :.|              |:|||:|||.|
  Rat   362 ---GGVC---------------SAKRKCVLAEDNGLNLAF--------------TIAHELGHNLG 394

  Fly   612 SPHDYPQECRPGGLNGNYIMFASATSGDRPNNSKFSPCSIRNISNVLDVLVGNTKRDCF-----K 671
            ..||.......|   .::||......|..|::..:|.||..::.|.|...|..    |.     :
  Rat   395 MNHDDDHSSCAG---RSHIMSGEWVKGRNPSDLSWSSCSRDDLENFLKSKVST----CLLITDPR 452

  Fly   672 ASEGAFCGNKI----VESGEECDC--GFNEEECKDKCCYPRLISEYDQSLNSSAKGCTRRAKTQC 730
            :.......:|:    ..:.|:|..  |.|...||:.           :.|..:...|.....|.|
  Rat   453 SQHALRLPHKLPGMHYSANEQCQILFGTNATFCKNM-----------EHLMCAGLWCLVEGDTSC 506

  Fly   731 SPSQGP------C-----CLSNSC---TFVPTSYHQKCKEETECSWS-----STCN---GTTA-- 771
            .....|      |     |.:..|   |.:|        |..:..||     |.|:   ||.|
  Rat   507 KTKLDPPLDGTECGADKWCRAGECVSKTPIP--------EHVDGDWSPWSAWSMCSRTCGTGARF 563

  Fly   772 ---ECPEPRHRDDKTMCNNGTALCIRGECSGSPC----------------LLWNMTKCFLTSTTL 817
               :|..|......|.|..  |......|...||                .|.:..:..||:.
  Rat   564 RQRKCDNPPPGPGGTHCQG--ASVEHAACENLPCPKGVPSFRDQQCQAHDRLSSKKRGLLTAM-- 624

  Fly   818 PHVSKRKLCDLACQDGNDTSTCRSTSEFADKYNIQKGGISLQPGSPCDNFQGYCDVFLKCRAVDA 882
              |...|.|:|.|......|.........|             |:||..::....|:.:|:.:..
  Rat   625 --VVDDKPCELYCSPLGKESPLLVADRVLD-------------GTPCGPYETDLCVYGRCQKIGC 674

  Fly   883 DG 884
            ||
  Rat   675 DG 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kuz	NP_477187.1	ZnMc_TACE_like	410..677	CDD:239798	63/316 (20%)
		Reprolysin_2	450..659	CDD:290307	50/245 (20%)
		Disintegrin	684..776	CDD:278623	25/120 (21%)
Adamts17	XP_218753.6	Pep_M12B_propep	61..179	CDD:279848
		AANH_like	168..>244	CDD:294206	13/64 (20%)
		Reprolysin	230..447	CDD:279729	55/267 (21%)
		ZnMc_ADAMTS_like	230..447	CDD:239801	55/267 (21%)
		TSP1	544..596	CDD:214559	14/53 (26%)
		ADAM_spacer1	698..808	CDD:283607
		TSP_1	893..946	CDD:278517
		TSP1	950..>981	CDD:214559
		TSP1	1001..1053	CDD:214559
		PLAC	1080..1106	CDD:285849

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910