Protein Alignment kuz and Adam9

DIOPT Version :10

• Sequence 1: NP_477187.1
• Gene: kuz / 34772
• FlyBaseID: FBgn0259984
• Length: 1238
• Species: Drosophila melanogaster
• Sequence 2: XP_063131318.1
• Gene: Adam9 / 290834
• RGDID: 621473
• Length: 909
• Species: Rattus norvegicus
• Alignment Length: 865
• Identity: 187/865 - (21%)
• Similarity: 271/865 - (31%)
• Gaps: 297/865 - (34%)

  Fly   380 VHERVRRATDNGAGDRGSSGGSGRGREDNKNTCSLYIQTDPLIWRHIREGIADHDRGRKYEVDEK 444
            ||:...|.   |..:|.:...:.:|.|:.          .|.:.:.:|...|...:.|..|:...
  Rat   168 VHQEPLRC---GVSNRDTEQEATQGEEEE----------HPSVTQLLRRRRAVLPQTRYVELFIV 219

  Fly   445 TREEITSLIAHHVTAV--------NYIYRNTKFDGRTEHRNIRFEVQRIKIDDDSACRNSYNGPH 501
            ..:|..:::..:.|||        ||:      |......|||..:..::|..|....|...|..
  Rat   220 VDKERYNMMGRNQTAVREEMIRLANYL------DSMYIMLNIRIVLVGLEIWTDRNPINIIGGAG 278

  Fly   502 NAFCNEHMDVSNFLNLHSLEDHSDFCLAYVFTYRDFTGGTLGLAWVASASGAS--GGICEKYKTY 564
            :...|.......||......|.:...|...|      |||.|:|:|.:....|  |||
  Rat   279 DVLGNFVQWREKFLITRRRHDSAQLVLKKGF------GGTAGMAFVGTVCSRSHAGGI------- 330

  Fly   565 TETVGGQYQSTKRSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPHDYPQECRPGGLNGNY 629
              .|.||            ||...:.|.|         |||:|||.|..||..:||.....:
  Rat   331 --NVFGQ------------ITVETFASIV---------AHELGHNLGMNHDDGRECFCAAKS--- 369

  Fly   630 IMFASATSGDRPNNSKFSPCSIRNISNVL-----DVLVGNTKRDCFKASEGAFCGNKIVESGEEC 689
            .:..|..||.|    .||.||..:...:.     ..|:...|.|  :|.....||||:|:.||||
  Rat   370 CIMNSGASGSR----NFSSCSAEDFEKLTLNKGGSCLLNIPKPD--EAYSAPSCGNKLVDPGEEC 428

  Fly   690 DCGFNEEECK-DKCCYPRLISEYDQSLNSSAKGCTRRAKTQCSPSQGPCCLSNSCTFVPTSYHQK 753
            ||| ..:||: |.||                :|.|.:.|:....:.|.||  ..|.|:|..  ..
  Rat   429 DCG-TPKECELDPCC----------------EGSTCKLKSFAECAYGDCC--KDCQFLPGG--SM 472

  Fly   754 CKEET-ECSWSSTCNGTTAECPEPRHRDDKTMCNNGTALCIRGECS--GSPCLLWNMTK------ 809
            |:.:| ||.....|||::..||......:...|.|..|.|..|.|.  .:.|.:...:|
  Rat   473 CRGKTSECDVPEYCNGSSQFCPPDVFIQNGYPCWNSKAYCYNGVCQYYDAQCQVIFGSKAKAAPR 537

  Fly   810 -CFLTSTTLPHVSKRKLCDLACQDGNDTSTCRSTSEFADKY---NIQK----------------- 853
             ||:...     ||..........|::..||.:.:....|.   |:|:
  Rat   538 DCFIEVN-----SKGDRFGNCGVSGSNYKTCATGNALCGKLQCENVQEMPVFGIVPAIIQTPSRG 597

  Fly   854 ---GGISLQPGSP------------------CDNFQ-------GY-CDVFLKCR----------- 878
               .|:..|.||.                  |.|||       .| ||:..||.
  Rat   598 TKCWGVDFQLGSDVPDPGMVNEGTKCDAGKICRNFQCVNASVLNYDCDIQGKCHGHGVCNSNKNC 662

  Fly   879 ------------------AVDADGPLLRLKNLLLNRKTLQTVAEWIVDNWYLVV-LMGVAFIVVM 924
                              :||: ||....|:..|.        :.::..::|:: |:..||.:
  Rat   663 HCEDGWAPPHCDTKGYGGSVDS-GPTYNAKSTALR--------DGLLVFFFLIIPLVAAAFFL-- 716

  Fly   925 GSFIKCCAVHTPSSNPKKRRARRISETLRAPMNTLRRMQRHPNQRGAGPRSIPPPAHEAQHYSRG 989
              ||            |:...|:.....|:.|:..|      ||..|.    .||...:.....|
  Rat   717 --FI------------KRDELRKTFRKKRSQMSDGR------NQANAS----RPPGDPSVSRPPG 757

  Fly   990 GD--GRGGGGGGGGRHGGSRSHHQQHPHDWDRHQGGHSIVPLPTGGSHSSRNSAANQARR----- 1047
            |.  .|..||....|..|.        .:..|..||.|:...|....|.|..:.:..|.|
  Rat   758 GPSVSRPPGGPNVSRPPGG--------PNVSRPPGGPSVSRPPVSPHHVSPVTPSRDAIRFIKNC 814

  Fly  1048 ----------SDGRGPRSTS------------------------------------------SGR 1060
                      ....|.|..|                                          .|.
  Rat   815 LLLCSSVVHLKTQTGARRVSRGDTHPYCAYNCRFDLQFQIQKRKIQKWLHSLNLDNYMLGNIEGG 879

  Fly  1061 PQAIASGSGAASGAARSHGG 1080
            ||...:..|..||..:.:||
  Rat   880 PQIEGTSRGLVSGCEKRYGG 899

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kuz	NP_477187.1	Pep_M12B_propep	54..149	CDD:460254
		ZnMc_TACE_like	410..677	CDD:239798	65/281 (23%)
		Disintegrin	684..776	CDD:459709	30/93 (32%)
Adam9	XP_063131318.1	None