Protein Alignment kuz and Adam26a

DIOPT Version :9

• Sequence 1: NP_477187.1
• Gene: kuz / 34772
• FlyBaseID: FBgn0259984
• Length: 1238
• Species: Drosophila melanogaster
• Sequence 2: NP_001162590.1
• Gene: Adam26a / 290763
• RGDID: 1559501
• Length: 710
• Species: Rattus norvegicus
• Alignment Length: 558
• Identity: 133/558 - (23%)
• Similarity: 194/558 - (34%)
• Gaps: 189/558 - (33%)

  Fly   395 RGSSGGS-------GRGREDNKNTCSLYIQTDPLI--------WRHIR--EGIADHDRGRKYEVD 442
            |..||.|       |...||......|....|.::        |.|.|  |..|..|..|....:
  Rat   161 RMDSGASESFPMRCGLSEEDIARQIKLQESNDSILLQIPYENWWTHHRFIEYFAVIDHKRYVHRN 225

  Fly   443 EKTREEITSLIAHHVTAVNYIYRNTKFD---------GRTEHRNIRFEVQRIKIDDDSACRNSYN 498
            ..|...|..:: ..|..:|..|.....|         .:..|.|:...:..:..|
  Rat   226 NNTTTCIQDML-QMVNGLNGYYHQIDTDVVLTTLEVWNKKNHVNVEQTLHNVLQD---------- 279

  Fly   499 GPHNAFCNEHMDVSNFLNLHSLEDHSDFCLAYVFTYRDFTGGTLGLAWVASASGASGGICEKYKT 563
                 |||        ..::.:..|..:.:.::|...|: ...||||.||:       :|...
  Rat   280 -----FCN--------WKVNMIGSHVRYDIIHLFVRHDY-DMYLGLANVAT-------VCTPD-- 321

  Fly   564 YTETVGGQYQSTKRSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPHDYPQECRPGGLNGN 628
                            |..:.:|:   |.|...:: ..:|||:|||.|..||         :||
  Rat   322 ----------------NCAVNSFI---SSVMSDMA-FIVAHEMGHNLGMKHD---------VNG- 356

  Fly   629 YIMFASATSG--------DRPNNSKFSPCSIRNISNVLDVLVGNTKRDCFKASEGA------FCG 679
                  .|.|        .:.|:.|||.||...:.:|:      |:|.|...:..|      .||
  Rat   357 ------CTCGLEDCIMAPYKSNSPKFSNCSHEEMYSVV------TQRKCLYNTPEALVTNLTMCG 409

  Fly   680 NKIVESGEECDCGFNEEEC-KDKCCYPRLISEYDQSLNSSAKGCTRRAKTQCSPSQGPCCLSNSC 743
            ||:||.||:|||| |.|.| ||.||               :|.|..:...||  :.|.||  .:|
  Rat   410 NKLVEKGEQCDCG-NLESCLKDPCC---------------SKDCVLKPGAQC--AFGLCC--KNC 454

  Fly   744 TFVPTSYHQKC-KEETECSWSSTCNGTTAECPEPRHRDDKTMCNNGTALCIRGECSGSPCLLWNM 807
            .|:.|.  ..| ||:.||.....||||:.|||...:::|...| :|...|.:..|.
  Rat   455 QFLQTG--TVCRKEKNECDLPEWCNGTSPECPRDVYKEDGNPC-SGDGYCYKMACH--------- 507

  Fly   808 TKCFLTSTTLPHVSKRKLCDLACQD--GNDTSTCRSTSEFADKYNIQKGGISLQPGSPCDNFQGY 870
                      .|       |..|:.  ||.:   ||..|.......::|          |.| |.
  Rat   508 ----------QH-------DEQCRKIFGNGS---RSAGEICYTEMNKRG----------DRF-GN 541

  Fly   871 C----DVFLKCRAVDADGPLLRLKNL--LLNRKTLQTV 902
            |    ..:.:|:..|.....::.:|:  |..||..:||
  Rat   542 CGNDSSKYRRCKRADVFCGRIQCENVTELPQRKNHETV 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kuz	NP_477187.1	ZnMc_TACE_like	410..677	CDD:239798	59/299 (20%)
		Reprolysin_2	450..659	CDD:290307	44/225 (20%)
		Disintegrin	684..776	CDD:278623	36/93 (39%)
Adam26a	NP_001162590.1	Pep_M12B_propep	42..160	CDD:396235
		ZnMc_adamalysin_II_like	208..396	CDD:239797	54/263 (21%)
		Disintegrin	414..486	CDD:395147	36/93 (39%)
		ACR	491..626	CDD:214743	26/130 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D162519at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010