Protein Alignment kuz and Adamdec1

DIOPT Version :9

• Sequence 1: NP_477187.1
• Gene: kuz / 34772
• FlyBaseID: FBgn0259984
• Length: 1238
• Species: Drosophila melanogaster
• Sequence 2: XP_017455116.1
• Gene: Adamdec1 / 290338
• RGDID: 1309861
• Length: 468
• Species: Rattus norvegicus
• Alignment Length: 592
• Identity: 110/592 - (18%)
• Similarity: 195/592 - (32%)
• Gaps: 211/592 - (35%)

  Fly   170 TTSSATTATKSTQPTR-------PLAKSNTSTTAVNSKTENFIKKIAESTTTSQQL--------- 218
            |..:.||.|...:|.:       |:::..   ...|::||::.|:...:.....|:
  Rat    28 TQVTDTTLTAELKPQKIVHPKKLPISQRR---GLENNQTESYAKEERYAPEVQYQIILNGEEIIF 89

  Fly   219 ----------PEYTESSSSSTTTFPPTTEYFEDEKERNAEDELDFHSIIYKESHVEDAYENVREG 273
                      |:|||.|      :.|..|    |..|.:::.    ...|.|.|:::|     :|
  Rat    90 HLKRTKHLLGPDYTEIS------YSPRRE----EMTRRSQNV----KPCYYEGHIQNA-----KG 135

  Fly   274 HVAGCGITDEVSQWMENIQNSAVEELPEPMSKDYQKLHRKQLHKKSAPQQQQQPHPPKKYISGDE 338
            .:|.....|.:..:.                     .||.|.::....|...:          .|
  Rat   136 SLASISTCDGLRGYF---------------------THRDQKYQIMPLQSTDE----------GE 169

  Fly   339 DFKYPHQKYTKEANFAE-GAFYDPSTGRRLGSSANVADWHQLVHERVRRATDNGAGDRGSSGGSG 402
            ....||       |:.| ||.....:.:::|...:        |.|..|:..:...|      |.
  Rat   170 HAVIPH-------NWEEPGAVNYKHSEKQIGRKRS--------HLRTSRSLKSPNED------SL 213

  Fly   403 RGREDNKNTCSLYIQTDPLIWRHIREGIADHDRGRKYEVDEKTREEITSLIAHHVTAVNYIYRNT 467
            :|::    ...|::..|...::..:..:              ||  :.|.:...:..:|.||:..
  Rat   214 QGQK----YIGLFLVLDNSYYKMYKGNV--------------TR--MRSFVFEVLNLLNVIYKTI 258

  Fly   468 KFDGRTEHRNIRFEVQRIKIDDDSACRNSYNGPHNAFCNEHMDVSNFLNLH------SLEDHSDF 526
            ..........|..:..:||:                ..|.....:||:..|      .:.:|
  Rat   259 DIQVSLVGMEIWSDRDKIKV----------------VPNLGATFTNFMRWHYSNLGQRIHNH--- 304

  Fly   527 CLAYVFTYRDFTGGTLGLAWVASASGASGGICEKYKTYTETVGGQYQSTKRSLNTGIITFVNYNS 591
              |.:.:...|..|.:|:|       |:..:|.     |.:|  .....||..|..::..
  Rat   305 --AQLLSGAGFLHGRVGMA-------AANSLCT-----TSSV--SVIEAKRKNNVALVAL----- 348

  Fly   592 RVPPKVSQLTLAHEIGHNFGSPHDYP--QECRPGGLNGNYIMFASATSGDRPNNSKFSPCSIRNI 654
                      ::||:||..|. .|.|  .:|..|....|..:           :||| |.....:
  Rat   349 ----------MSHELGHALGM-QDVPYYTKCPSGSCVMNQYL-----------SSKF-PKDFSTV 390

  Fly   655 S-----------NVLDVLVGNTKRDCFKASEGAFCGNKIVESGEECDCGFNEEECKDKCCYP--- 705
            |           |...:|:....::..|.:    |||::::.||.|||| :.|||.:.||.|
  Rat   391 SRSRFQGFLSSRNTRCLLLAPDPKNIIKPT----CGNRLLDMGEGCDCG-SPEECTNLCCEPLTC 450

  Fly   706 RLISEYD 712
            ||.|:.|
  Rat   451 RLKSQPD 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kuz	NP_477187.1	ZnMc_TACE_like	410..677	CDD:239798	46/285 (16%)
		Reprolysin_2	450..659	CDD:290307	40/227 (18%)
		Disintegrin	684..776	CDD:278623	16/32 (50%)
Adamdec1	XP_017455116.1	Pep_M12B_propep	54..175	CDD:279848	26/173 (15%)
		Reprolysin	217..411	CDD:279729	45/276 (16%)
		ZnMc_adamalysin_II_like	217..408	CDD:239797	44/273 (16%)
		Disintegrin	427..>454	CDD:299186	14/27 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339794
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D162519at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940