Protein Alignment kuz and ADAMDEC1

DIOPT Version :9

• Sequence 1: NP_477187.1
• Gene: kuz / 34772
• FlyBaseID: FBgn0259984
• Length: 1238
• Species: Drosophila melanogaster
• Sequence 2: NP_055294.1
• Gene: ADAMDEC1 / 27299
• HGNCID: 16299
• Length: 470
• Species: Homo sapiens
• Alignment Length: 514
• Identity: 99/514 - (19%)
• Similarity: 161/514 - (31%)
• Gaps: 147/514 - (28%)

  Fly   243 KERNAEDELDFHSIIYKESHVEDAYENVREGHVAGCGITDEVSQWMENIQNSAVEEL---PEPMS 304
            ||...|.|:.:..|:..|   |......:..|:.|       ..:.|.:.:...||:   ||.|.
Human    68 KEERYEPEVQYQMILNGE---EIILSLQKTKHLLG-------PDYTETLYSPRGEEITTKPENME 122

  Fly   305 KDYQKLHRKQLHKKSAPQQQQQPHPPKKYISGDEDFKYPHQKY----TKEANFAEGAFYDPSTGR 365
            ..|.|  ...|::|::..........:.|      |.:.||:|    .|..:..|.|.:
Human   123 HCYYK--GNILNEKNSVASISTCDGLRGY------FTHHHQRYQIKPLKSTDEKEHAVF------ 173

  Fly   366 RLGSSANVADWHQLVHERVRRATDNGAGD-RGSSGGSGRGRED---NKNTCSLYIQTDPLIWRHI 426
                ::|..:.....|....::||...|. |.|.......:||   .:....||:..|...:::.
Human   174 ----TSNQEEQDPANHTCGVKSTDGKQGPIRISRSLKSPEKEDFLRAQKYIDLYLVLDNAFYKNY 234

  Fly   427 REGIADHDRGRKYEVDEKTREEITSLIAHHVTAVNYIYRNTKFDGRTEHRNIRFEVQRIKIDDDS 491
            .|.:.                .|.|.:...:..:|.||.............|..:..:||:...:
Human   235 NENLT----------------LIRSFVFDVMNLLNVIYNTIDVQVALVGMEIWSDGDKIKVVPSA 283

  Fly   492 ACRNSYNGPHNAFCNEHMDVSNFLNLHS------LEDHSDFCLAYVFTYRDFTGGTLGLAWVASA 550
            :                ....|||..||      :.||:.......|..|     .:|||
Human   284 S----------------TTFDNFLRWHSSNLGKKIHDHAQLLSGISFNNR-----RVGLA----- 322

  Fly   551 SGASGGICEKYKTYTETVGGQYQSTKRSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPHD 615
              ||..:|.....       .....|:..|..::.               .::||:||..|.| |
Human   323 --ASNSLCSPSSV-------AVIEAKKKNNVALVG---------------VMSHELGHVLGMP-D 362

  Fly   616 YP--QECRPGGLNGNYIMFASATSGDRPNNSKFSPCSIRNISNVLDVLVGNTKRDCF-------K 671
            .|  .:|..|....|..:           :|||......:.....:..:.:.|..|.       .
Human   363 VPFNTKCPSGSCVMNQYL-----------SSKFPKDFSTSCRAHFERYLLSQKPKCLLQAPIPTN 416

  Fly   672 ASEGAFCGNKIVESGEECDCGFNEEECKDKCCYPRLISEYDQSLNSSAKGCTRRAKTQC 730
            ......|||.::|.||:|||| :.:||.:.||              .|..|..:..|.|
Human   417 IMTTPVCGNHLLEVGEDCDCG-SPKECTNLCC--------------EALTCKLKPGTDC 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kuz	NP_477187.1	ZnMc_TACE_like	410..677	CDD:239798	45/281 (16%)
		Reprolysin_2	450..659	CDD:290307	38/216 (18%)
		Disintegrin	684..776	CDD:278623	15/47 (32%)
ADAMDEC1	NP_055294.1	Pep_M12B_propep	54..172	CDD:279848	26/121 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	173..200		5/36 (14%)
		Reprolysin	218..412	CDD:279729	45/271 (17%)
		ZnMc_adamalysin_II_like	218..409	CDD:239797	45/268 (17%)
		Disintegrin	429..>461	CDD:299186	15/47 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146050
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D162519at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.850