Protein Alignment kuz and Adam34

DIOPT Version :9

• Sequence 1: NP_477187.1
• Gene: kuz / 34772
• FlyBaseID: FBgn0259984
• Length: 1238
• Species: Drosophila melanogaster
• Sequence 2: NP_665688.2
• Gene: Adam34 / 252866
• MGIID: 2181992
• Length: 714
• Species: Mus musculus
• Alignment Length: 537
• Identity: 122/537 - (22%)
• Similarity: 187/537 - (34%)
• Gaps: 196/537 - (36%)

  Fly   291 IQNSAVEELPEPMSKDYQKLHRKQLHKKSAPQQQQQPHPPKKYISGDEDFKYPHQKYTKEANFAE 355
            |..:..|.:|:..:..::.|..|..:.:|      :|.|.:..:|.:|   ...|...:|:| |.
Mouse   138 INGTTYEIMPKSTTSTFEHLAYKMDNGES------EPSPMRCGLSEEE---IAQQMKLQESN-AS 192

  Fly   356 GAFYDPS----TGRRLGSSANVADWHQLVHERVRRATDNGAGDRGSSGGSGRGREDNKNTC---- 412
            .....|.    |..|......|.|.::.||                       |.:|..||
Mouse   193 TLLQIPYENWWTHHRFIDYFVVIDHNRYVH-----------------------RNNNTTTCIQDM 234

  Fly   413 ----------SLYIQTDPLIWRHIREGIADHDRGRKYEVDEKTREEITSLIAHHVTAVNYIYRNT 467
                      .|.||||.::                      |:.|:.|             :|.
Mouse   235 LQVVNGINGYYLQIQTDVVL----------------------TKLEVWS-------------QNN 264

  Fly   468 KFDGRTEHRNIRFEVQRIKIDDDSACRNSYNGPHNAFCNEHMDVSNFLNLHSLEDHSDFCLAYVF 532
            ..       |:..|::::.               .||||        ..::::.:.....:.::|
Mouse   265 LI-------NVEQEIRKVL---------------GAFCN--------WKINAIGNRVRHDIIHLF 299

  Fly   533 TYRDFTGGTLGLAWVASASGASGGICEKYKTYTETVGGQYQSTKRSLNTGIITFVNYNSRVPPKV 597
            ..|.: |..||||.|       |.:|                  .:||..:      ||.:...:
Mouse   300 VRRSY-GTYLGLANV-------GTVC------------------LTLNCAV------NSFLSDSL 332

  Fly   598 SQLT--LAHEIGHNFGSPHDYPQECRPGGLNGNYIMFASATSGDRPNNSKFSPCSIRNISNVLDV 660
            |.:.  :|||:|||.|..|| ...|..|       :.:...:..:.|:.|||.||...:.:|:
Mouse   333 SDMAFIIAHEMGHNLGMMHD-GSSCTCG-------LSSCIMAPYKSNSPKFSNCSYEEMFSVV-- 387

  Fly   661 LVGNTKRDCFKASEGA---------FCGNKIVESGEECDCGFNEEECKDKCCYPRLISEYDQSLN 716
                |||.|......|         .|||.:||.|||||||..|...:|.||
Mouse   388 ----TKRSCLYDIPDALKTINLMPTMCGNNLVEEGEECDCGSTESCLQDPCC------------- 435

  Fly   717 SSAKGCTRRAKTQCSPSQGPCCLSNSCTFVPTSYHQKCKEE-TECSWSSTCNGTTAECPEPRHRD 780
              :..|..:...||  :.|.||  .:|.|:.|.  ..|:|| .||.....||||:||||...::.
Mouse   436 --SSDCVLKPGAQC--AFGLCC--KNCQFLKTG--TVCREEKNECDLPEWCNGTSAECPGDVYKA 492

  Fly   781 DKTMCNNGTALCIRGEC 797
            |...| :|...|.:.||
Mouse   493 DGIPC-SGEGYCYKMEC 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kuz	NP_477187.1	ZnMc_TACE_like	410..677	CDD:239798	55/291 (19%)
		Reprolysin_2	450..659	CDD:290307	41/210 (20%)
		Disintegrin	684..776	CDD:278623	34/92 (37%)
Adam34	NP_665688.2	Pep_M12B_propep	41..159	CDD:366707	4/20 (20%)
		ZnMc_adamalysin_II_like	207..395	CDD:239797	61/321 (19%)
		Disintegrin	416..488	CDD:365943	34/92 (37%)
		ACR	492..628	CDD:214743	6/18 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836131
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D162519at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.850