Protein Alignment kuz and LOC103690152

DIOPT Version :10

• Sequence 1: NP_477187.1
• Gene: kuz / 34772
• FlyBaseID: FBgn0259984
• Length: 1238
• Species: Drosophila melanogaster
• Sequence 2: NP_001420266.1
• Gene: LOC103690152 / 103690152
• RGDID: 9083574
• Length: 723
• Species: Rattus norvegicus
• Alignment Length: 878
• Identity: 166/878 - (18%)
• Similarity: 243/878 - (27%)
• Gaps: 391/878 - (44%)

  Fly    39 EYISHYETLNYDHEHIRASHNRARRSVTKDQYVHLKFASHGRD--FHLRLKRDL-NTFSNKLDFY 100
            :|:|..|.:      |........|.....:::....|..||.  .|:|:|:.| :|..:.|.:.
  Rat    40 QYLSSPEVV------IPLKVTSGARDAKNSEWLSYSLAFGGRRHVVHMRVKKLLVSTHFSVLTYT 98

  Fly   101 DSKGPID----VSTDHIYEGEVIGDRNSYVFGSIHNGVFEGKIITERDAYYVEHAKH-------Y 154
            :...|:.    |.:|..|.|.|.|...|.|..|..:|.|:|.:.....:|.:|..||       .
  Rat    99 EEHAPLSDYPFVPSDCYYHGYVEGAPESLVAFSSCSGGFQGVLQMNGFSYEIEPIKHSSTFEHLV 163

  Fly   155 FPTNRTATTTPPSTSTTSSATTATKSTQPTRPLAKSNTSTTAVNSKTENFIKKIAESTTTSQQLP 219
            :..|...|..||      .....|:.|.|.:|........:||.   :|:.|
  Rat   164 YTLNNNKTQFPP------MICNLTEKTLPDQPFGLKEEEKSAVK---QNYRK------------- 206

  Fly   220 EYTESSSSSTTTFPPTTEYFEDEKERNAEDELDFHSIIYKESHVEDAYENVREGHVAGCGITDEV 284
                        ..|.|.:.|      ....:|::...|.:.:|    ..||...|....:.|.:
  Rat   207 ------------LWPHTWFLE------LAVVVDYNFFTYSQQNV----SKVRGDVVLVVNMVDSM 249

  Fly   285 SQWMENIQNSAVEELPE-----PMSKDYQKLHRKQLHKKSAPQQQQQPHPPKKYISGDEDFKYPH 344
            .:.|:...|....|:..     ||....|.|                           |||.:
  Rat   250 YKQMDTYVNLVGIEIWNRGNLLPMENIQQVL---------------------------EDFSH-- 285

  Fly   345 QKYTKEANFAEGAFYDPSTGRRLGSSANVADWHQLVHERVRRATDNGAGDRGSSGGSGRGREDNK 409
                                           |.|:...:|
  Rat   286 -------------------------------WKQISLSQV------------------------- 294

  Fly   410 NTCSLYIQTDPLIWRHIREGIADHDRGRKYEVDEKTREEITSLIAHHVTAVNYIYRNTKFDGRTE 474
                                                         ||
  Rat   295 ---------------------------------------------HH------------------ 296

  Fly   475 HRNIRFEVQRIKIDDDSACRNSYNGPHNAFCNEHMDVSNFLNLHSLEDHSDFCLAYVFTYRDFTG 539
                           |:|               |:.:.|.|.
  Rat   297 ---------------DAA---------------HIFIRNSLI----------------------- 308

  Fly   540 GTLGLAWVASASGASGGICEKYKTYTETVGGQYQSTKRSLNTGIITFVNYNSRVPPKVSQLTLAH 604
            ..||:|:||       |||   :...:.....:|....||      |.|            |:||
  Rat   309 SVLGIAYVA-------GIC---RPPLDCGVENFQGDSWSL------FAN------------TVAH 345

  Fly   605 EIGHNFGSPHDYPQECRPGGLNGNYIMFASATSGDRPNNSKFSPCS----IRNISNVLDVLVGNT 665
            |:||.||..|| .:.|..|  ....:|     |..|....:|:.||    ::...|....|..:.
  Rat   346 ELGHTFGMRHD-EESCSCG--EKGCVM-----SSFRVPAERFTNCSHSDFMKTTLNQGSCLYNHP 402

  Fly   666 KRDCFKASEGA-----FCGNKIVESGEECDCGFNEEECKDKCCYPRLISEYDQSLNSSAKGCTRR 725
            :       .||     .|||.||||.||||||...|..:|.||               ...||.:
  Rat   403 R-------PGAGFLVKRCGNGIVESEEECDCGSIRECEQDPCC---------------LFNCTLK 445

  Fly   726 AKTQCSPSQGPCCLSNSCTFVPTSYHQKCKEE-TECSWSSTCNGTTAECPEPRHRDDKTMCNNGT 789
            ....|  :.|.||  ..|.|:...  :.|:.: .||.....||||:.:|||..:..|...| ...
  Rat   446 PGAAC--AFGLCC--KDCKFMLLG--ELCRAKINECDLPEWCNGTSHQCPEDGYVQDGVPC-GAR 503

  Fly   790 ALCIRGECSGSPCLLWNMTKCFLTSTTLPHVSKRKLCDLACQD--GNDTSTCRSTSEFADKYNIQ 852
            |.|.:.:|:|.                          |..|::  |..   .||.|     :|..
  Rat   504 AYCYQKQCNGH--------------------------DQQCREVFGKG---ARSAS-----HNCY 534

  Fly   853 KGGISLQPGSPCDNFQGYC----DVFLKCRAVD 881
            |     :..|....| |:|    .|:|||...|
  Rat   535 K-----EINSQGTRF-GHCGTNGTVYLKCSVSD 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kuz	NP_477187.1	Pep_M12B_propep	54..149	CDD:460254	25/101 (25%)
		ZnMc_TACE_like	410..677	CDD:239798	42/275 (15%)
		Disintegrin	684..776	CDD:459709	29/92 (32%)
LOC103690152	NP_001420266.1	Pep_M12B_propep	46..164	CDD:460254	29/123 (24%)
		ZnMc_adamalysin_II_like	212..400	CDD:239797	61/434 (14%)
		Disintegrin	419..491	CDD:459709	29/92 (32%)
		ACR	495..631	CDD:214743	23/108 (21%)