Protein Alignment kuz and adam28.1

DIOPT Version :9

• Sequence 1: NP_477187.1
• Gene: kuz / 34772
• FlyBaseID: FBgn0259984
• Length: 1238
• Species: Drosophila melanogaster
• Sequence 2: NP_001233133.1
• Gene: adam28.1 / 100488450
• XenbaseID: XB-GENE-982024
• Length: 780
• Species: Xenopus tropicalis
• Alignment Length: 852
• Identity: 181/852 - (21%)
• Similarity: 288/852 - (33%)
• Gaps: 291/852 - (34%)

  Fly   299 LPEPMSKDYQKLHRKQLHKKSAPQQQQQPHPPKKYISGDEDFKYP----------------HQKY 347
            ||:|.:.  |||.....::...|::....|  |:.:.|    .||                |.:.
 Frog    14 LPQPAAS--QKLTIDPYYEVVFPKKIHAQH--KRDVQG----MYPEVVQYGIHMGGKHLILHLEK 70

  Fly   348 TKE---ANFAEGAFYDPSTGRRLGSSANVADWHQLVHERVRRATDNG--------AGDRGSSGGS 401
            .::   ||:.|  .|..|.|..:.:|..:.: |......|:  .|||        :|.||.....
 Frog    71 NEDLLSANYTE--TYYLSDGTPVTTSPKIQN-HCYYQGNVK--NDNGSLASISTCSGLRGLIQTE 130

  Fly   402 GR-------------------GREDNKNTCSLYIQT--DPLIWRHIREG---------------- 429
            |:                   .:.:...||.:...|  :.::.:..|.|
 Frog   131 GQMYLIEPLKDTDSESHAVYEAQMETPKTCGVDNTTYREEIVVKKSRSGSSAEQQQILKAQKYIR 195

  Fly   430 ---IADHDRGRKYEVDEKTREEITSLIAHHVTAVNYIYRNTKFDGRTEHRNIRFEVQRIKID--- 488
               :||:....||   .|:...:...|...:..||.:|           :.|...|..|.|:
 Frog   196 LVVVADNSMFIKY---NKSITNVKIRIFEVINFVNVVY-----------KAINTFVALIGIEVWN 246

  Fly   489 --DDSACRNSYNGPHNAFCNEHMDVSNFLNLHSLEDHSDFCLAYVFTYRDFTGGTLGLAWVASAS 551
              |......|.:....||.:..   .|.|...:..|:     |.:.|..||.|.|:|||:|
 Frog   247 TTDQFKVVTSASADLAAFADWR---KNVLLRRTPNDN-----AQLLTNTDFDGATVGLAYV---- 299

  Fly   552 GASGGICEKYKTYTETVGGQYQSTKRSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPHDY 616
               |..|.:    |.:.|.....:|.|:..|                 .|:|||:|||.|..||
 Frog   300 ---GTECSE----THSAGVIQDHSKASIGVG-----------------ATVAHELGHNLGMNHD- 339

  Fly   617 PQECRPGGLNGNYIMFASATSGDRPNNSKFSPCSIRNISNVL------DVLVGNTKRDCFKASEG 675
            ...|   ..:.:..:.|...|.:.|.  .||.||::|..:.|      .:|....|.|....
 Frog   340 TDSC---SCSASSCIMAPYLSVNTPR--LFSSCSLQNYQDFLLSRMPQCMLAVPLKEDIIAP--- 396

  Fly   676 AFCGNKIVESGEECDCGFNEEECKDKCCYPRLISEYDQSLNSSAKGCTRRAKTQCSPSQGPCCLS 740
            |.||||..|.||:|||| ..|||.::||              .|..|..::..:|  ::|.||
 Frog   397 AVCGNKFTEIGEDCDCG-TVEECTNQCC--------------DAATCKLKSTAKC--AEGDCC-- 442

  Fly   741 NSCTFVPTSYHQKCK-EETECSWSSTCNGTTAECPEPRHRDDKTMCNNGTALCIRGEC--SGSPC 802
            ::|......  ..|: .:.:|..:..|:|.::.||..|.|.:...|:||...|..|:|  ..|.|
 Frog   443 DNCQIKKAG--SVCRAAKDDCDLADMCDGKSSVCPSDRFRVNGFPCSNGKGYCFNGKCPTHQSQC 505

  Fly   803 -LLWNMT------KCFLTSTT--------------LPHVSKRKLCD-LACQDGN----------D 835
             .||..:      .||..:|.              :|...|...|. |.|..|:          :
 Frog   506 TTLWGASSVPSEDSCFNVNTRGVDYGYCTMAGATYVPCKPKDVKCGMLFCYGGSSQPSIYAAVAE 570

  Fly   836 TSTCRSTSEFADKYNIQKGGISLQPGSPCDN----FQG----------------------YCDVF 874
            .|.||:.        :.:||: :|.|:.|.:    :.|                      .||..
 Frog   571 FSRCRAV--------LAQGGM-VQNGTKCGDGMVCYNGACSSIESAYRSTNCSAQCSGHAVCDHE 626

  Fly   875 LKCRAVDADGP----LLRLKNLLLNRKTLQTVAEWIVDNWYLVVLMGVAFIVVMG---------- 925
            :.|:..:...|    :....|:::                 :||::.:|..:|:|
 Frog   627 MLCQCEEGWAPPTCDVASPTNIII-----------------IVVVIVIALALVIGLVFLARFYRG 674

  Fly   926 --------SFIKCCAVHTPSSNPKKRRARRISETLRAPMNTLRRMQRHPNQRGAGPRSIPPP--A 980
                    ||.....|. .|:||..|..       ..|...:...|.| ..:.|..:|.||.  .
 Frog   675 KGKKQSSSSFPATVTVE-GSTNPSFRNQ-------PPPQMQMPLPQVH-KPKPATDKSWPPSRVG 730

  Fly   981 HEAQHYS 987
            ::|..||
 Frog   731 YQAPQYS 737

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kuz	NP_477187.1	ZnMc_TACE_like	410..677	CDD:239798	65/298 (22%)
		Reprolysin_2	450..659	CDD:290307	52/219 (24%)
		Disintegrin	684..776	CDD:278623	25/92 (27%)
adam28.1	NP_001233133.1	Pep_M12B_propep	30..150	CDD:366707	23/130 (18%)
		ZnMc_adamalysin_II_like	192..385	CDD:239797	57/248 (23%)
		Disintegrin	405..477	CDD:365943	25/92 (27%)
		ACR	482..601	CDD:214743	28/127 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D162519at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920