DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kuz and XB5838589

DIOPT Version :9

Sequence 1:	NP_477187.1	Gene:	kuz / 34772	FlyBaseID:	FBgn0259984	Length:	1238	Species:	Drosophila melanogaster
Sequence 2:	XP_002933016.3	Gene:	XB5838589 / 100145070	XenbaseID:	XB-GENE-5838590	Length:	441	Species:	Xenopus tropicalis

Alignment Length:	471	Identity:	84/471 - (17%)
Similarity:	144/471 - (30%)	Gaps:	148/471 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 GKIITERDAYYVEHAKHYFPTNRTATTTPPSTSTTSSATTATKSTQPTRPLAKSNTSTTAVNSKT 201
            |.|.||:|.|                     ....||...|.:...|.:..::..|.    |.|.
Frog    31 GLIATEQDWY---------------------KQDWSSELQAYEIIDPLKIQSRGQTE----NEKV 70

  Fly   202 ENFIKKIAESTTTSQQLPEYTESSSSSTTTFPPTTEYFEDEK----ERNAEDELDFHSII--YKE 260
            ...|:  .|......:|.:..||..|:...|    .|.:|.|    |...:|...:|..:  |.|
Frog    71 TFLIR--TEEKPLLLRLKQKRESVLSNMKVF----TYGKDNKLIADEPYMQDSCYYHGFVEGYPE 129

  Fly   261 SHVEDA----------YENV----------------------REGHVAGCGITDEV--------- 284
            |.|..:          |||.                      |.|::| ||:..:.
Frog   130 SSVSLSSCTGLRGFIQYENFSYRIEPLDPLRTSKHIMYRSENRVGNLA-CGLNFKTKTPSLQLSS 193

  Fly   285 -------------------SQWMENIQN-----SAVEELPEPMSKDYQKLHRKQLHKKSAPQQQQ 325
                               :.|...:||     |.:.|:...|...:|.::.:.:
Frog   194 PVSYRGGEPMYIEFAVVVSNNWYRQVQNISQIVSEITEMVNLMDDMFQSINIRII---------- 248

  Fly   326 QPHPPKKYISGDEDFKYPHQKYTKEANFAEGAFYDPSTGRRLGSSANVADWHQLVHERVRRATDN 390
                           ....:.:|.| ||:..:   .|:|..:.:..|.....:.|| ||....:.
Frog   249 ---------------LIAIEVWTNE-NFSVAS---SSSGEHILTEFNKWKQREFVH-RVFSDIEG 293

  Fly   391 GAGDRGSSGGSGRGREDNKNTCSLYIQTDPLIWRHI----REGIADHDRGRKYEVDEKTREEITS 451
            ...||..|.|.|.    ..|.|.........:::|.    |..|..|:.|....::..|.|...:
Frog   294 FVIDRAPSAGMGY----TGNACKKSFSHSFAVFKHFDVVERALIFAHNLGHSLGMEHDTDESCEN 354

  Fly   452 LIAHHVTAVNYIYRNTKFDGRTEHRNIRFEVQRIKIDDDS-ACRNSYNGPHNAFCNEHMDVSNFL 515
            .|.|.....|..:.......... .:|..::..:|.:..: :..||.|..|..:|:...:..:::
Frog   355 CIMHCCAMYNLSFSEQSHSALIA-EDIGGKLLCLKNEPSTESLFNSGNWMHGKYCDRGSEKPSYI 418

  Fly   516 NLHSLEDHSDFCLAYV 531
            .|..:     |.||::
Frog   419 LLSLV-----FFLAFI 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kuz	NP_477187.1	ZnMc_TACE_like	410..677	CDD:239798	23/127 (18%)
		Reprolysin_2	450..659	CDD:290307	14/83 (17%)
		Disintegrin	684..776	CDD:278623
XB5838589	XP_002933016.3	Pep_M12B_propep	59..167	CDD:396235	23/117 (20%)
XB5838589	XP_002933016.3	ZnMc_adamalysin_II_like	203..389	CDD:239797	36/220 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D162519at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010