Protein Alignment Hsp60D and groL

DIOPT Version :10

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_418567.1
• Gene: groL / 948665
• ECOCYCID: EG10599
• Length: 548
• Species: Escherichia coli
• Alignment Length: 546
• Identity: 204/546 - (37%)
• Similarity: 323/546 - (59%)
• Gaps: 14/546 - (2%)

  Fly    17 ANDIRFGAEARCLLMQGVNVLANAVATTLGPKGRNVLIEQLLISPRITKDGITVANNVQLGNRRQ 81
            |.|::||.:||..:::||||||:||..|||||||||::::...:|.|||||::||..::|.::.:
E. coli     3 AKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFE 67

  Fly    82 DMGVQLLRQATNNTNNKVGDGTTTATILARGIACQGMHVLRQSKVNVQLLREGILEGSRAVCDAL 146
            :||.|::::..:..|:..||||||||:||:.|..:|:..: .:.:|...|:.||.:...|..:.|
E. coli    68 NMGAQMVKEVASKANDAAGDGTTTATVLAQAIITEGLKAV-AAGMNPMDLKRGIDKAVTAAVEEL 131

  Fly   147 GEMSQSVDTIGQVEAVAKVALNGDERLAELIGDIILELGDSGVILLKESHSPFDEAKIQEGITIA 211
            ..:|........:..|..::.|.||.:.:||.:.:.::|..|||.:::.....||..:.||:...
E. coli   132 KALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFD 196

  Fly   212 SGYYSPFFAKQSHT--LELENCLLLLTLAKIDQVEQILPALELARLKERPLLIIAKNFGSDLLKI 274
            .||.||:|..:..|  :|||:..:||...||..:.::||.||......:||||||::...:.|..
E. coli   197 RGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALAT 261

  Fly   275 LVLNNLQGRVQVCAVKAPSFGDEQCEEMEDIAFATGGHLL--EDASSLADLSEEDLGEVMEAVVD 337
            ||:|.::|.|:|.|||||.|||.:...::|||..|||.::  |....|...:.||||:....|::
E. coli   262 LVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVIN 326

  Fly   338 AKETHLLQPINVNEEQVQCRIQDIRELIDEAFTDVELDRLKTRLGRLQGHLATIFVGGTSELEVS 402
            ...|.::..:. .|..:|.|:..||:.|:||.:|.:.::|:.|:.:|.|.:|.|.||..:|:|:.
E. coli   327 KDTTTIIDGVG-EEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMK 390

  Fly   403 ERKDRFNDALHAVRVAISDGVVPGGGTAYLRCIPVLDELPPTDIMELQVGREIVKDALRLPCYTI 467
            |:|.|..|||||.|.|:.:|||.|||.|.:|....|.:|...: .:..||.::...|:..|...|
E. coli   391 EKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQN-EDQNVGIKVALRAMEAPLRQI 454

  Fly   468 ARNAGVDPNEVLRRVLKGSGNYGYDAAAGEFGDLVVRGIVDPTKVLQSAMTSAAGIASLLATTEV 532
            ..|.|.:|:.|...|..|.|||||:||..|:|:::..||:|||||.:||:..||.:|.|:.|||.
E. coli   455 VLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTEC 519

  Fly   533 LITKQPTKPKIPKNQVTKDLAKLVGM 558
            ::|      .:|||... ||....||
E. coli   520 MVT------DLPKNDAA-DLGAAGGM 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	GroEL	18..536	CDD:239460	195/521 (37%)
groL	NP_418567.1	groEL	2..530	CDD:234573	200/535 (37%)